An online detector

A detector and detector technology, applied in the field of online detectors, can solve problems such as long time consumption, achieve the effect of fast detection speed and improve detection efficiency

Active Publication Date: 2019-04-02
DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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Problems solved by technology

However, as a complex biological sample, blood must be pretreated before chromatographic separation, which makes the above methods time-consuming and mostly offline analysis, which cannot fully meet the needs of clinical anesthesia monitoring.

Method used

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  • An online detector

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Embodiment Construction

[0024] The online detector of propofol in blood adopts the traditional homogeneous field mobility spectrometry, and its structure diagram is shown in figure 1 . This instrument mainly includes the following parts: 1 is the micro sample injector, 2 is the upper partition of the sample injector bracket, 3 is the sample injector bracket, 4 is the rotating turntable with a built-in sampling disk, 5 is the rotary motor, and 6 is the drive. Motor, 7 is the thermal analysis chamber, 8 is the carrier gas inlet of the injector, 9 is the sample gas outlet of the injector, 10 is the inlet of the sample gas entering the transfer tube, 11 is the ionization area of ​​the transfer tube, 12 is the ion gate of the transfer tube, 13 14 is the migration tube grid, 15 is the ion receiving electrode of the migration tube, 16 is the drift gas inlet, and 17 is the gas outlet of the migration tube.

[0025] The micro sample injector 1 takes 10-100uL of blood samples and drops them on the surface of ...

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Abstract

The invention designs an online detector. The instrument uses ion mobility spectrometry as the basic detection technology, uses a rotating motor to control the sample injection turntable, and combines sample thermal analysis and headspace sampling technology. Samples are collected to the surface of the sampling sheet without complex pretreatment, and the rotating motor controls the sample injection turntable, so that the samples on the sampling sheet can be continuously injected for thermal analysis, and then carried by the carrier gas into the detector for online detection and analysis. The on-line detector in the invention is used for continuous on-line detection of propofol anesthetic in human blood during operation, and guides doctors to administer clinically.

Description

technical field [0001] The invention is based on the ion mobility spectrometry technology, utilizes the working principle of a rotary motor, and combines the sample thermal analysis and headspace sampling technology to design an on-line detector. The detection device and method of the present invention are used for clinical blood concentration analysis of propofol anesthetic in blood, and can guide clinical anesthesiologists to use drugs precisely. Background technique [0002] Rotating electrical machines are divided into three categories: DC motors, three-phase asynchronous motors, single-phase AC motors, etc. The principle of rotation of the DC motor is that the current-carrying conductor rotates under the force of the magnetic field. The rotation of the DC motor is that the magnetic field does not move, and the conductor moves. [0003] Thermal analysis technology is a two-in-one technology: it integrates sampling and concentration, and then transfers the sample from th...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N27/62
Inventor 李海洋李恩有王新李东明鞠帮玉李庆运
Owner DALIAN INST OF CHEM PHYSICS CHINESE ACAD OF SCI
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