Cordyceps militaris polysaccharide, extracting method and application thereof in aspect of preparing functional constipation treating medicine
A technology of Cordyceps militaris polysaccharide and extraction method, which is applied in the field of polysaccharide medicine, and can solve the problems of poor curative effect, toxic and side effects, etc.
Active Publication Date: 2017-05-31
HENAN UNIVERSITY
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- Abstract
- Description
- Claims
- Application Information
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Problems solved by technology
For patients with irritable bowel syndrome, although their constipation is functional constipation, they must go to the hospital for further examination
At present, most of the drugs used to treat functional constipation on the market have defects such as poor curative effect and toxic side effects.
Method used
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Embodiment 1
[0015] The Cordyceps militaris polysaccharide is obtained through the following steps: take 1920g of a sample of Cordyceps militaris, add water to submerge the medicinal materials, decoct with water (a total of 2 decoctions, 1 hour for the first time, 0.5 hours for the second time), combine the two filtrates and add Absolute ethanol until the final concentration of ethanol is 70V%, put it in the refrigerator overnight (12h), centrifuge, and the obtained precipitate is freeze-dried (frozen at -40°C for 12h, dried in a dryer), and then it is Cordyceps militaris polysaccharide. About 50g.
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The invention discloses an extracting method of cordyceps militaris polysaccharide. The extracting method comprises the steps of decocting cordyceps militaris in water, filtering, adding absolute ethyl alcohol into filtrate until the ethyl alcohol concentration is 70+ / -5V%, standing and separating solid from liquid. The obtained sediment is the cordyceps militaris polysaccharide. The invention further discloses application of the cordyceps militaris polysaccharide in an aspect of preparing functional constipation treating medicine. Experiments show that the cordyceps militaris polysaccharide disclosed by the invention can obviously improve the content of motilin (MTL), gastrin (GAS), somatostation (SS) and P substance in serum and improve functional constipation. Therefore, the cordyceps militaris polysaccharide is ideal medicine for treating the functional constipation.
Description
technical field [0001] The invention belongs to the technical field of polysaccharide medicines, and in particular relates to a polysaccharide from Cordyceps militaris, an extraction method and its application in the preparation of medicines for treating functional constipation. Background technique [0002] Functional constipation (functional constipation, FC) is a functional gastrointestinal disease, which refers to a functional gastrointestinal disease whose symptoms originate in the middle and lower gastrointestinal tract. Constipation caused by changes in the law of life, emotional depression, dietary factors, bad bowel habits, drug effects, etc. Constipation, this kind of constipation is functional constipation. [0003] Generally speaking, functional constipation is manifested as persistent difficulty in defecation, reduced frequency of defecation, or a sense of incomplete defecation. It does not meet the diagnostic criteria of irritable bowel syndrome and meets cert...
Claims
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Login to View More IPC IPC(8): C08B37/00A61K31/715A61P1/10
CPCA61K31/715A61K36/068C08B37/0003C08B37/006
Inventor 康文艺卓宝松辛昕王学标
Owner HENAN UNIVERSITY