72results about How to "Does not cause drug resistance" patented technology

The invention belongs to the field of biotechnology and particularly relates to Bacillus subtilis and application thereof. The Bacillus subtilis is Bacillus subtilis HS5B5. The strain is preserved in China General Microbiological Culture Collection Center, with the preservation number of CGMCC No. 6088. The Bacillus subtilis HS5B5 provided by the invention has a very strong restraining effect on the pathogen Cladosporiwm paeoniae of brown spot of peony, and can effectively prevent and cure brown spot of peony. The Bacillus subtilis HS5B5 is harmless to the ecological environment and cannot cause the resistance of the pathogen. The Bacillus subtilis HS5B5 is cultured under simple conditions, is easy to preserve, facilitates industrial production and has a favorable development and application prospect.

A wettable fungus protein powder for increasing the resistance of crops to diseases and pests and the yield of crops by 10-30% is prepared from fungus protein, diatomite, surfactant, Na2EDTA, sodium thiosulfate, and phosphoric acid buffering liquid prepared from sodium bihydrogen phosphate and bisodium hydrogen phosphate. Its advantages are high stability and action durability, no poison and no environmental pollution.

The invention discloses a traditional Chinese medicine for treating chronic renal failure. The traditional Chinese medicine comprises rhubarb, junesnow, asiatic pennywort herb, herb pyrolae, honeysuckle, calcined fossilizid, calcined oyster shell, rheum officinale carbon, radix aconiti lateralis preparata, rhizoma zingiberis, cortex cinnamomi, sophora flower bud, Chinese angelica, herba leonuri, manis pentadactyla, semen coicis, bighead atractylodes rhizome and poria cocos, wherein rhubarb and cortex cinnamomi are finally added, and the calcined fossilizid, the calcined oyster shell and the radix aconiti lateralis preparata are firstly decocted. The decoction of the traditional Chinese medicine for treating chronic renal failure is prepared by adopting the following steps of: soaking Chinese medicinal herbs in three containers, wherein calcined fossilizid, calcined oyster shell and radix aconiti lateralis preparata which are firstly decocted are soaked in a decoction pot, because the decoction time of calcined fossilizid, calcined oyster shell and radix aconiti lateralis preparata which are firstly decocted is longer, the water quantity can be properly increased; soaking rhubarb and cortex cinnamomi which are added finally in another container, wherein the added water is slightly higher than the surface of rhubarb and cortex cinnamomi; and soaking the rest of the Chinese medicinal herbs in the third container, wherein the added water is slightly higher than the surface of the rest of the Chinese medicinal herbs. The traditional Chinese medicine can be used for effectively eliminating toxins in a human body of a patient suffering from the chronic renal failure and relieving symptoms of the patient, and has a remarkable treatment effect on the chronic renal failure.

The present invention relates to a medicine composition for curing human and animal vaginal infection. Said medicine composition includes probiotics capable of producing beta-hydroxy-propionaldehyde (beta-HPA), glycerine, beta-hydroxypropionaldehyde and natamycin. The invented medicine composition can inhibit and kill various vaginal pathogenic bacteria and fungi.

The invention discloses a health-care growth promoting feed additive for nutria at a replacement period and application thereof. The additive comprises the following components: white chrysanthemum, mulberry leaf, brown rice bud, Chinese yam, Chinese date, nostoc commune, honeysuckle leaf, Chinese pulsatilla root, fructus quisqualis and sweet wormwood; and the components are proportioned. When the additive is used, the additive is 2 to 6 percent of the mass of the basal feed, and the additive is fed once every 2 weeks and continuously fed for 3 days every time; and when an epidemic situation occurs, the dose of the additive is increased to 6 percent, and the additive is continuously fed for 3 days. The average weight gain of each experimental group using the additive at the age of 210 days is increased by 10.04 to 18.77 percent compared with a blank contrast group, and the incidence is reduced by 54 to 58 percent compared with the blank contrast group. According to the digestive physiological characteristics and the disease occurrence law of the nutria at the replacement period and the compatible principle of Chinese medicaments, the medicament components are synergic and exert respective advantages, so that the additive has the effects of preventing and treating diseases, promoting growth and the like.

The invention relates to a cuttage breeding method for increasing survival rate of speed grows willows. The cuttage breeding method comprises the following steps: (1) selecting branches to be subjected to cuttage; (2) preserving the branches to be subjected to cuttage; (3) processing cuttage planting soil; (4) processing the branches to be subjected to cuttage; (5) processing cuttage planting branches; (6) performing cuttage; (7) managing after cuttage. According to the cuttage breeding method disclosed by the invention, the processed speed grows willows are high in survival rate, fewer in plant diseases and insect pests, and more in grown seedling numbers per unit area.

The invention discloses a preparation method of an ion response type antibacterial and anticorrosive coating, which comprises the steps of firstly, preparing a SiO2 nano container through liquid phase mixing and reflux condensation, then mixing the nano material with an antibacterial agent, carrying out ultrasonic treatment to obtain a nano container loaded with the antibacterial agent, then packaging the nano container by adopting a FeIII-TA complex molecular film, finally, according to a basic method for preparing the coating, adding the functional filler into the matrix coating, then adding a coating additive, and stirring at a high speed to obtain the ion response type antibacterial and anticorrosive coating. The selected coating is a water-based coating, the antibacterial agent is triclosan (TCS), and the coating and the antibacterial agent have the characteristics of being green and environment-friendly and do not contain harmful components. In the using process, harm to the human body and the environment is avoided, and the coating has the characteristics of self-repairing, long antibacterial aging and excellent corrosion resistance.

The invention relates to a traditional Chinese medicinal composition for treating hepatic fibrosis and a preparation method for treating the traditional Chinese medicinal composition. The traditionalChinese medicinal composition is prepared from the following raw materials in parts by weight: 5-15 parts of radix bupleuri, 10-30 parts of turtle shell processed by vinegar, 10-30 parts of radix salviae miltiorrhizae, 10-30 parts of radix astragali, 10-30 parts of rhizoma atractylodis macrocephalae, 10-30 parts of poria cocos, 10-30 parts of codonopsis pilosula, 10-30 parts of rhizoma cyperi processed by vinegar, 10-30 parts of rhizoma curcumae processed by vinegar, 10-30 parts of rhizoma atractylodis fried with bran, 15-45 parts of herba sedi, 10-30 parts of radix angelicae sinensis, 10-30 parts of red paeony root, 10-30 parts of radices paeoniae alba, 5-15 parts of pericarpium citri reticulatae viride processed by vinegar, 5-15 parts of dried orange peel, 10-30 parts of phyllanthus urinaria and 10-30 parts of rhizoma alismatis. The traditional Chinese medicinal composition provided by the invention, for patients with hepatic fibrosis, chronic hepatic disease and hepatic disease in final stage, can be used for effectively treating the hepatic fibrosis and improving repair power of liver; and the traditional Chinese medicinal composition is free from toxic and side effects and isfree from drug tolerance.

The invention discloses a Chinese medicinal preparation for resisting coccidiosis and a preparation method thereof. The Chinese medicinal preparation is prepared by extracting, concentrating and refining the following raw material drugs in parts by weight: 2 to 10 parts of Chinese rhubarb, 1 to 10 parts of common bletilla pseudobulb, 1 to 10 parts of garden burnet, and 2 to 10 parts of hairyvein agrimony. According to the Chinese medicinal preparation for resisting coccidiosis and the preparation method thereof, the preparation is prepared by extracting, concentrating and preparing the Chinese medicinal drugs, has the effects of clearing heat and cooling blood, and astringing to stop bleeding, and is used for treating bloody stools caused by coccidiosis; and the Chinese medicinal preparation is simple in preparation and high in safety, and convenient to drink (mixed drinking with 2.5 to 5g for each chick), cannot cause drug resistance, and is advantageous to treatment of coccidiosis.

The invention relates to a Chinese medicament for treating kidney failure, and belongs to the technical field of Chinese medicaments. The medicament for treating chronic kidney failure comprises the following active ingredients in part by weight: 10 to 20 parts of astragalus, 4 to 9 parts of heterophylly falsestarwort root, 5 to 15 parts of Indian buead, 4 to 10 parts of large-headed atractylodes rhizome, 8 to 15 parts of Chinese caterpillar fungus, 8 to 15 parts of twotooth achyranthes root, 15 to 20 parts of prepared common monkshood daughter root and 10 to 20 parts of rhubarb. The medicament for treating the kidney failure can improve the microcirculation of the kidney effectively, promote blood circulation and remove blood stasis, increase flow of renal blood and improve human immunity, has no toxic or side effect for long-term administration, does not cause medicinal tolerance, and has low cost and obvious curative effect on the kidney failure.

The invention discloses fig oral cavity spray and a preparation method thereof. The fig oral cavity spray is composed of, on the basis of 1000ml, 50 g to 150 g of fig fruit extract freeze-dried powder, 2 g to 6 g of preservative, 40 g to 80 g of absorption promoter and the balance deionized water. The absorption promoter is prepared from Herba Clinopodii Chinensis saponin and cholate. The fig oral cavity spray has the effects of inhibiting bacteria, diminishing inflammation, stopping bleeding, smoothing the throat, removing odors and the like, is convenient to use and meets the needs of modern people for oral hygiene and health. The preparation method of the fig oral cavity spray is easy to operate and control and suitable for industrial production and has high promotional value.

The invention discloses an extracting method of cordyceps militaris polysaccharide. The extracting method comprises the steps of decocting cordyceps militaris in water, filtering, adding absolute ethyl alcohol into filtrate until the ethyl alcohol concentration is 70+/-5V%, standing and separating solid from liquid. The obtained sediment is the cordyceps militaris polysaccharide. The invention further discloses application of the cordyceps militaris polysaccharide in an aspect of preparing functional constipation treating medicine. Experiments show that the cordyceps militaris polysaccharide disclosed by the invention can obviously improve the content of motilin (MTL), gastrin (GAS), somatostation (SS) and P substance in serum and improve functional constipation. Therefore, the cordyceps militaris polysaccharide is ideal medicine for treating the functional constipation.

The invention provides a multienzyme compound capable of preventing and treating fungus infection. The multienzyme compound of the invention can be used in daily prevention of fungus infection, and can kill fungi selectively without generation of toxic or side effects, or drug resistance. The multienzyme compound of the invention can treat fungus infection individually. Because the multienzyme compound can digest fungus cell walls, when cooperated with other antifungal medicaments to treat fungus infection, the multienzyme compound of the invention can promote penetration of other medicaments, enhance treatment effects of other medicaments effectively, reduce dosage and application amount, lower toxic and side effects, and reduce generation probability of drug resistance. In addition, the multienzyme compound of the invention can be selectively added with antifungal medicaments to improve treatment effects.

Disclosed is a medicament for treating AIDS, wherein the active constituents include Fucoidan-Glycocalyx polymeric compound, which is a protein polysaccharide containing sulfate groups extracted from Chinese herbal sea apron. The preparing process consists of steps of choosing materials, soaking and cleaning, disintegrating, water extracting, low concentration alcohol depositing, high concentration depositing, purifying to obtain the end product.

The invention relates to a pesticide for soil insect control for salix integra. The pesticide is prepared from following components by weight: 2.5 parts of dipterex, 2 parts of thifluzamide, 3 parts of copper hydroxide, 2 parts of fleeceflower root, 1 part of giant knotweed rhizome, 2.4 parts of cortex phellodendri, 1.8 parts of Chinese chive seed, 3.2 parts of bidens biternata, 2.7 parts of murraya jasminorage, 4 parts of ashycoloured ironweed and 2.2 parts of large-flowered thunbergia, wherein traditional Chinese medicine components are compounded in a form of traditional Chinese medicine extracts. By compounding of a plurality of medicines, the pesticide has good insect-killing, insect-preventing and antibacterial effects. The traditional Chinese medicine extracts are added, so that insect-killing and insect-preventing effects are improved, the pesticide has contact toxicity and stomach toxicity functions and good insect killing effects, and the pesticide has the antibacterial effects.

The invention discloses a vaginal suppository for treating mycotic vaginitis as well as preparation and use methods of the vaginal suppository. The vaginal suppository comprises a medicine carrier and traditional Chinese medicine liquid, wherein the medicine carrier comprises a medicine-loaded pad and a pull-out line; the medicine-loaded pad is a bacterial cellulose freeze-dried membrane; the pull-out line is fixedly arranged at the center of the bottom surface of the medicine-loaded pad; the effective constituents of traditional Chinese medicine liquid comprise the following crude drugs: flos daturae, herba leucas chinensis, flos caryophylli, resina liquidambaris, herba dendrobii, peppermint leaves, rhizoma coptidis, fructus cnidii, rhizoma smilacis glabrae, radix gentianae, rhizoma polygoni cuspidati, borneolum syntheticum, radix saposhnikoviae, periostracum cicadae, herba bulbophylli odoratissim, radix astragali, radix zanthoxyli nitidi, semen citri reticulatae, flos rosae rugosae, rhizoma paridis chinensis and galla chinensis. According to the prepared vaginal suppository, the traditional Chinese medicine liquid and the medicine carrier are stored separately; when the vaginal suppository is used, a syringe is used for sucking the traditional Chinese medicine liquid, then pushing the medicine-loaded pad to the vulvovaginal deep part and finally injecting the medicine liquid. The vaginal suppository is used for treating mycotic vaginitis, is convenient to use and good and fast in efficacy, can treat both manifestation and root cause of disease, has no toxic side effects, and the disease is unlikely to relapse after healing.

The invention discloses a beef cattle health growth-promoting feed additive and an application thereof. The additive comprises the following components: semen raphani, Indian strawberry, potentilla chinensis, Sedum sarmentosum, longan aril, Gorgon fruit, stone-like omphalia, pumpkin seeds, Melastoma affine, Chinese yam, Polygonum posumbu and Ailanthus altissima, and the various components are used for preparing the additive according to a ratio. During use, the additive accounts for 1.5-3.5 percent of the mass of basal feed, and the feed is fed once every two weeks and is continuously fed by 2 days each time; and in the period of beef cattle disease epidemics, the dosage is increased to 3.5 percent, and the feed is continuously fed for 3 days. By utilizing the tested groups of the additive disclosed by the invention, the average weight gain is higher than that of a blank control group, and the incidence rate is lower than that of the blank control group. According to the physiological characteristics and disease occurrence rules of beef cattle, the combination principle of the traditional Chinese medicine is considered, the various component medicines coordinate and supplement with one another, and the additive has the effects of preventing and treating diseases, promoting the growth and the like.

The invention relates to a method for extracting malus halliana flower polysaccharide, and is characterized in that the method comprises the steps: carrying out heating reflux of dried malus hallianaflowers with petroleum ether, then taking a residue, and soaking with ethanol; after the end of soaking, taking out the residue, adding water and decocting; and after the end of decoction, filtering,adding 95% ethanol to the filtrate until the final concentration is 70-85%, allowing to stand, taking a precipitate, and leaching with anhydrous ethanol, acetone and petroleum ether respectively, wherein the obtained precipitate after leaching is the malus halliana flower polysaccharide. The invention also discloses an application of the malus halliana flower polysaccharide in preparation of drugsfor treating functional constipation. Tests find that the malus halliana flower polysaccharide can significantly increase the content of motilin (MTL), gastrin (GAS) and P substances in serum, reduces the content of somatostatin (SS) and improves functional constipation. The malus halliana flower polysaccharide is indicated to be an ideal drug for treating functional constipation.

The invention provides a Chinese herbal additive for chicken feed and application thereof, and belongs to the technical field of poultry feed processing. The Chinese herbal additive is prepared by mainly processing eritrichium, rubus lambertianus root, honeysuckle, thunbergia fragrans, mountain passionflower, radish leaf, shaddock peel, meehania henryi, gorse, helixanthera parasitica lour., myrioptmeron extensum, rhaphidophora peepla, psychotria serpens, phyllanthus urinaria Linn., smilax perfoliata lour, aletris spicata, sarcococca ruscifolia stapf, embelia laeta (L.), chelidonium majus and dodder in certain proportions by weight. The Chinese herbal additive for the chicken feed has medicinal and nutritional dual effects, and can prevent diseases, can regulate the immunity of a chicken, improve functions of the spleen and the stomach of the chicken, promote growth of the chicken and improve the productivity; the used raw materials are environment-friendly natural, do not cause drug residues and drug resistance, and are free of toxic and side effects, safe and reliable.

The invention discloses a sterilizing deodorant. The sterilizing deodorant is prepared from the following substances in percentage by weight: 0.7 to 1.2 percent of soybean ethyl sulfate morpholine, 9 to 10 percent of dealdehyded alcohol, 0.3 to 0.7 percent of silver ion bactericide and 89.1 to 90 percent of DI water. According to the invention, the soybean ethyl sulfate morpholine is added, odor is eliminated through the bonding effect, and the unpleasant odor is not covered through the essence, so rapid odor removal is realized; and the silver ion bactericide is added, so sterilization treatment can be efficiently performed, long-acting antibacterial effect can be achieved, and the advantages of no toxicity, no odor, no stimulation no anaphylactic reaction, and no incurrence of drug resistance are achieved.

The invention discloses a sterilizing deodorant. The sterilizing deodorant is prepared from the following substances in percentage content: 0.7 to 1.2 percent of soybean ethyl sulfate morpholine, 4 to 8 percent of aldehyde-removed alcohol, 0.5 to 1.5 percent of beta-cyclodextrin, 0.3 to 0.7 percent of silver ion bactericide, 1 to 3 percent of pomelo peel, 0.5 to 1.2 percent of essence, 1 to 3 percent of Chinese hawthorn seed particles, 1.5 to 2.5 percent of a traditional Chinese medicine extract, 1.2 to 1.8 percent of a stabilizer and 89.1 to 90 percent of DI WATER. According to the sterilizing deodorant disclosed by the invention, the soybean ethyl sulfate morpholine is added, so that the odor is eliminated through a bonding effect; the pomelo peel and the essence are heated to further increase an odor removing function, so that the odor can be rapidly removed; and the silver ion bactericide and the Chinese hawthorn seed particles are added, sterilization treatment can be efficiently performed, the long-acting antibacterial effect can be provided, moreover, the sterilizing deodorant is non-toxic, tasteless, non-irritating and non-allergic, and will not cause bacterial resistance; and the traditional Chinese medicine extract is added, so that the protection effect on a human body can be improved.

The invention discloses a Chinese herbal medicine for preventing bacterial diseases of sturgeons, the raw materials of which include: Chinese gall, honeysuckle flower, liquorice root, ginger and bromochlorodimethylhydantoin. The raw materials further include: indigowoad leaf, Chinese goldthread rhizome, Mongolian dandelion herb, grassleaf sweelflag rhizome, ginkgo leaf, pomegranate rind, radix scutellariae, Chinese gentian, lightyellow sophora root, Chinese thorowax root, radix et rhizoma rhei and common andrographis herb. The Chinese herbal medicine adopts the traditional Chinese medicines to be coordinated with one another, the quality of sturgeons is effectively prevented from being affected, moreover, water cannot be polluted, and furthermore, the Chinese herbal medicine can clear heat and remove toxicity, has the multiple effects of resisting and inhibiting bacteria, enhancing the immunity of sturgeons and promoting the growth and development of sturgeons, can exert effects on a variety of bacterial diseases of sturgeons at the same time, and has a significant prevention and control effect on coinfected diseases of the fish body caused by a variety of pathogens.

The invention provides an additive for a chicken feed, belonging to the technical field of poultry feed processing. The additive is prepared by processing the following main components according to a weight proportion: Justicia championii, Lysimachia hui Diels, dandelion, root of Inula nervosa Wall., spinybract evergreenchinkapin seed, exocarpium citri grandis, immature bitter orange, emperor woodbetony root, root of Vitis flexuosa Thunb., corydalis tuber, Aleuritopteris squamosa herb, Munronia henryi Harms, buchanan cryptolepis root, root of Agalma delavayi, Orobanche yunnanensis herb, common physochlaina root, gallnut, balsam of Peru, dried orange peel and Rhizoma Dioscoreae Hypoglaucae. The additive for the chicken feed provided by the invention has double functions of medicinal properties and nutrition, can prevent diseases and regulate the immunity of chicken, improves spleen and stomach functions of the chicken, promotes the growth of the chicken, and improves production performance; meanwhile, the used raw materials are green and natural, do not cause drug residues and drug resistance, pose no toxic and side effects, and are safe and reliable.