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Composition for preventing goat brucellosis and preparation method thereof

A goat brucellosis and composition technology, applied in the field of goat brucellosis prevention composition and its preparation, can solve problems such as endangering the healthy development of goats, antibiotic residues in mutton, goat endocrine disorders, etc., and promote Sustained and healthy development, improved production performance, and significant preventive effects

Active Publication Date: 2021-03-16
广西璞缔恩葳生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In summary, it can be seen that the incidence of goat brucellosis is high, and its prevalence and hazards are extensive. Therefore, effective control of goat brucellosis is extremely important for improving the production performance of ewes, reducing economic losses, and promoting the sustainable and healthy development of sheep breeding industry. It is important, but at present, there are several reasons for goats infected with Brucella: 1. Due to the lack of management, because Brucellosis mainly affects the reproductive system, it often leads to misdiagnosis and delays the disease during diagnosis, making The spread of Brucella not only seriously endangers the healthy development of goats, but also may further infect humans with Brucella. 2. At present, there is no specific drug for Brucella. Generally, after Brucella in goats, a. According to the treatment methods of other reproductive system diseases, but there is no effect. b. Use some antibiotics for treatment, although it can relieve some symptoms, but it will cause endocrine disorders in goats, and it will cause goat milk and / or mutton Antibiotic residues are harmful to human health, so the use of safe, efficient and targeted methods to prevent goat brucellosis has become a research hotspot all over the world

Method used

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  • Composition for preventing goat brucellosis and preparation method thereof
  • Composition for preventing goat brucellosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A composition for preventing goat brucellosis, comprising the following raw materials in parts by weight: 20kg of yellow vine, 15kg of dandelion, 15kg of smilax, 10kg of bupleurum, 20kg of Chinese yam, 15kg of honeysuckle, 15kg of Daqingye, Gallbladder 10kg.

[0035] The mass ratio of the yellow vine stem to the yellow vine root is 2:0.8.

[0036] Weigh dandelion, Smilax, Bupleurum, Chinese yam, honeysuckle, Folium Folium, and Gentiana according to the formula, add water to boil, filter, concentrate the filtrate, mix the concentrate and ethanol at a mass ratio of 1:5, Heat to 45°C, reflux for 150min, recover ethanol, then add acetone of 3 times the mass of the concentrated solution, extract for 6 hours, recover acetone, and obtain a residual liquid, then extract Phytophthora fruticosa to obtain an extractant of Phytophthora fruticosa, and extract the residual liquid It is mixed with the extractant of yellow vine, then added with monosaccharide to adjust the sugar conte...

Embodiment 2

[0040] A composition for preventing goat brucellosis, comprising the following raw materials in parts by weight: 30kg of yellow vine, 30kg of dandelion, 30kg of smilax, 20kg of Bupleurum, 30kg of Chinese yam, 30kg of honeysuckle, 30kg of Daqingye, Gallbladder 20kg.

[0041] The mass ratio of the yellow vine stem to the yellow vine root is 2:1.2.

[0042] The preparation method of the tablet is to weigh dandelion, Smilax smilax, Bupleurum chinensis, Chinese yam, honeysuckle, Folium Folium, and Gentiana according to the formula, pulverize them, add water and decoct them into an extract with a water content of 20%, Then extract the Chinese vine to obtain the Chinese vine extract, mix the extract and the Chinese vine extract, add 20% compressible starch of the quality of the medical extract, and then add 0.5% of the total amount of magnesium stearate and mix well , compressed into tablets by a tablet machine to obtain tablets.

[0043] Described Huangteng extractant, can refer t...

Embodiment 3

[0046] A composition for preventing goat brucellosis, comprising the following raw materials in parts by weight: 25kg of yellow vine, 23kg of dandelion, 23kg of smilax, 15kg of bupleurum, 25kg of Chinese yam, 23kg of honeysuckle, 23kg of Daqingye, Gallbladder 15kg.

[0047] The mass ratio of the yellow vine stem to the yellow vine root is 2:1.

[0048] The preparation method of the capsule is as follows: taking dandelion, Smilax smilax, Bupleurum chinensis, yam, honeysuckle, Folium Folium, Gentiana according to the formula amount, crushing to obtain Chinese medicine powder, and then extracting Huang Teng to obtain Huang Teng The rattan extract is prepared by mixing the rattan extract and traditional Chinese medicine powder evenly, and wrapping the empty capsules prepared by methyl cellulose, alginate, polyvinyl alcohol or denatured gelatin to prepare capsules.

[0049] Described Huangteng extractant, can refer to the extraction disclosed in ("Optimization Research of Huangten...

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Abstract

The invention relates to the field of livestock drugs, in particular to a composition for preventing goat brucellosis and a preparation method thereof. The composition comprises the following raw materials: herba fibraureae recisae, taraxacum mongolicum, rhizoma smilacis glabrae, radix bupleuri, rhizoma dioscoreae, flos lonicerae, folium isatidis and radix gentianae. The composition has a remarkable prevention effect on goat brucellosis, and can effectively lower the incidence rate of goat brucellosis to be 2%; through reasonable compounding of the Chinese herbal medicines which can achieve a favorable synergistic effect, the function of preventing and controlling goat brucellosis is effectively achieved, and significance is achieved on improving the goat productivity, reducing economic loss and promoting sustained healthy development of the goat breeding industry.

Description

technical field [0001] The invention relates to the field of medicine for poultry and livestock, in particular to a composition for preventing goat brucellosis and a preparation method thereof. Background technique [0002] Goat brucellosis is a zoonotic infectious disease caused by Brucella. The main source of infection of brucellosis is the diseased and infected livestock. After the goat is infected, it mainly invades the reproductive system, causing the female goat to develop Abortion and mastitis, orchitis and epididymitis in male goats, under certain conditions, mainly through the digestive tract, followed by skin and mucous membrane infection. After goats are infected with Brucella, they often become chronic due to misdiagnosis and mistreatment. Cause recurrent outbreaks, long-term unhealed, and people will be infected with brucellosis because of contact with sick animals or animal products (such as mutton, goat milk and other pollutants) contaminated by Brucella, whic...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/90A61K36/896A61P31/04
CPCA61K36/195A61K36/233A61K36/288A61K36/315A61K36/355A61K36/515A61K36/59A61K36/704A61K36/855A61K36/8945A61K36/896A61K36/90A61K2236/331A61K2236/55A61K2300/00
Inventor 张艳雯郑一民田乾坤玉发杨
Owner 广西璞缔恩葳生物技术有限公司
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