Guide-in device and guide-in method

Abstract

The invention discloses a guide-in device and a guide-in method. The guide-in device is used for guiding exogenous molecules in a solution into cells, and comprises at least one hypersonic sound generating device used for generating hypersonic sound waves in the solution; the frequency of the hypersonic sound waves is 1GHz or higher; the hypersonic sound waves act on the cell membranes of the cells so as to form temporary through holes in the cell membranes to provide occasional passages for exogenous molecules to enter the cells. The hypersonic sound waves are excited through the hypersonic sound generating device in the solution; the hypersonic sound waves act with the cells, so that the instant nanometer level through holes can be generated in the cell membranes for providing the occasional passages for exogenous molecules to enter the cells; the barrier of the biosome skin or the cell membrane of the single cell can be broken, so that the exogenous molecules fast enter subcutaneous tissues or the insides of the cells; the medicine guide-in on the skin, the organs and the cells can be realized; the guide-in efficiency is improved. The guide-in device and the guide-in method have the advantages that the bio-compatibility is good; no obvious influence is realized on the cell activity.

Description

technical field [0001] The invention relates to an introduction device and an introduction method for introducing exogenous molecules into cells. Background technique [0002] In modern molecular biology, the safe and effective introduction of drugs (including drug molecules and genes) to biological individuals or cells is a key link. Since the cell membrane of the cell protects the interior of the cell from the interference of external molecules, the direct use of exogenous drugs or genes to interact with cells can achieve very little drug delivery effect. Therefore, people have developed various chemical or physical drug delivery methods to increase the permeability of the cell membrane, thereby increasing the rate and efficiency of exogenous molecules entering the cells, and achieving therapeutic effects. [0003] Chemical drug delivery methods usually use recombinant viruses or chemically synthesized carriers to combine with target exogenous molecules to reduce the barr...

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Problems solved by technology

[0006] For the above-mentioned problems in related technologies, no effective solution has been proposed yet

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