Application of silymarin in alleviating the reproductive toxicity of animal zearalenone

A technology of zearalenone and silymarin, which is applied in the application field of silymarin in alleviating the reproductive toxicity of animal zearalenone, can solve the problems that the application of ZEN reproductive toxicity antidote has not been reported, and achieve the goal of alleviating the reproductive toxicity effect Effect
CN107095866BActive Publication Date: 2019-12-10湖北润泛生物科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
湖北润泛生物科技有限公司
Publication Date
2019-12-10

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Abstract

The invention discloses application of silymarin in relieving of the reproductive toxicity of zeranol in animal corn. The silymarin is added into feed at the addition amount of 100 to 500mg / kg. By means of the silymarin, a reproductive toxicity effect caused by ZEN can be effectively relieved.
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Description

technical field

[0001] The invention relates to a new application of silymarin, in particular to an application of silymarin in alleviating the reproductive toxicity of animal zearalenone. Background technique

[0002] Zearalenone (Zearalenone, referred to as ZEN), also known as F-2 toxin, is a non-steroidal mycotoxin with estrogenic activity mainly produced by Fusarium graminearum, widely present in moldy corn, sorghum, Cereal crops such as wheat and milk. In 2009, the mycotoxin contamination test results of 90 feed and raw material samples from all over the country showed that the positive detection rate of ZEN in corn samples was as high as 84.6%, and the ZEN content in positive samples was as high as 229mg / kg (Zhang Cheng, 2009).

[0003] ZEN has the effect of estrogen, and its main action site on animals is the reproductive system. It can induce estrogen hyperactivity in domestic animals, poultry and experimental mice. Animals (including humans) are in pregnancy. If t...

Claims

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