Method for extracting hair-growing active component from Chinese arborvitae twigs

A technology of cypress leaves and extracting liquid, which is applied in the field of extracting active components of cypress leaves for hair growth, can solve problems such as ignorance and unclear material basis of cypress leaves, achieve obvious clinical effects, prevent hair loss and hair growth, and have low cost Effect

Inactive Publication Date: 2017-12-05

JILIN AGRICULTURAL UNIV

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Problems solved by technology

[0002] Arborvitae leaves (Cacluneu Platycladi), also known as clump cypress leaves, are the dry shoots and leaves of arborvitae; traditional Chinese medicine believes that arborvitae leaves are fragrant, bitter in taste, slightly cold in nature, non-toxic into the heart, liver and large intestine meridian; It has the functions of cooling blood, stopping bleeding, removing internal dampness, and dispelling swelling and poison; it can cure hematemesis, epistaxis, hematuria, bloody dysentery, metrorrhagia, rheumatic pain, cough, and...

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Abstract

The present invention discloses the optimal extraction solvent, extraction condition and the latest processing technology of the traditional Chinese medicine Arborvitae leaves for preventing hair loss and promoting hair growth. The two optimal solvents for extraction are lard and linseed oil respectively, and the optimal temperature for extraction is 110°C, the optimal concentration of the extract is 0.25g/ml, and the optimal extraction time is 30 minutes; and the original processing technology of steaming the leaves of oriental cypress leaves before making them into finished products; this method is used to prepare anti-hair loss and hair growth drugs, health care Products, cosmetics, food, etc. are low in cost and suitable for industrial production.

Application Domain

Cosmetic preparationsToilet preparations +4

Technology Topic

SolventActive component +5

Examples

Effect test(1)

Test Example

[0012] Test example:

[0013] The substance extracted by the present invention is proved to be the active ingredient for hair growth through the following tests:

[0014] 1. Materials

[0015] 1.1 the active ingredients for hair growth extracted by the present invention;

[0016] 1.2 Test animals: Kunming mice, weighing 20-22g, purchased from the Experimental Animal Center of Jilin University;

[0017] 2. Test method:

[0018] 2.1 Establishment of sodium sulfide hair removal model

[0019] 80 healthy adult Kunming male SD mice were fed with basal diet for 3-5 days, and the hair on their backs was cut off with scissors, with an area of about 2X3cm, and then coated with 8% sodium sulfide solution. This method induces the development of anagen hair follicles that can be highly synchronized, and the hair follicles are morphologically indistinguishable from spontaneously formed anagen hair follicles;

[0020] 2.2 Grouping and administration of experimental animals

[0021] 2.2.1 Grouping and administration of sodium sulfide hair removal model animals

[0022] The sodium sulfide hair removal model was used in mice to study the effect of oriental orientalis leaf on promoting normal hair growth; as to whether oriental orientalis leaf can attenuate hair loss caused by cyclophosphamide-induced hair follicle damage, and thus play a role in preventing hair loss, The study will be conducted by a concurrent trial of the preventive effect of hair loss;

[0023] Mice with smooth depilation area and no skin damage were selected and randomly divided into 8 groups: negative control group, high-dose lard group (Lard-G), medium-dose lard group (Lard-G), and low-dose lard group. Dosage group (Lard-G), high-dose linseed oil group (Linseed-G), medium-dose linseed oil group (Linseed-Z), low-dose linseed oil group (Linseed-D), positive control group;

[0024] The experimental mice were raised normally, and 0.3 mL of the test solution and positive drug were smeared on the back of the mice from the second day after hair removal, and the mice used for the experiment of promoting hair growth were smeared and administered continuously for 12 days;

[0025] 2.2.2 Experimental observation and evaluation methods

[0026] The mice in the chemotherapy model group were observed daily for hair loss, and were scored according to the standard of 0 points for no hair loss, 1 point for sparse hair loss on the head, neck and back, 2 points for moderate hair loss on the head, neck and back, and 3 points for obvious hair loss on the head, neck and back. The hair loss of mice was scored, and the results were analyzed by rank sum test (hair loss score); for mice that promoted hair growth, no hair growth was scored as 0, a small amount of fine hair was scored as 1, and obvious hair was scored as 2. Good hair growth is scored 3 points, hair growth is no different from normal mice, 4 points, and the situation is marked with "*";

[0027] in conclusion

[0028] Through experimental research, the optimal extraction solvent and extraction conditions for preventing hair loss and promoting hair growth of traditional Chinese medicine orientalis leaves were found. The two optimal solvents for extraction were lard and linseed oil. The optimal concentration of the liquid is 0.25g/ml, and the optimal extraction time is 30min. As a traditional Chinese medicine for medicine and food, oriental orientalis leaves have very obvious effects on promoting hair growth, preventing hair loss, hair growth, and black hair. It has been developed into health food, medicine, toiletries, etc., making arborvitae leaves benefit human beings widely.

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Description & Claims & Application Information

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the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine

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Application of combination of hydrolyzed yeast protein and chicory root extract in preparation of hair growing and nourishing products

ActiveCN113230163APromote blood circulationPromote hair growthCosmetic preparationsHair cosmeticsChicory root extractGrowth cycle

Owner:宁波见睿新材料有限公司

Classification and recommendation of technical efficacy words

Promote hair growth

Method for extracting hair-growing active component from Chinese arborvitae twigs

AI-Extracted Technical Summary

Problems solved by technology

Abstract

Examples

Test Example

PUM

Description & Claims & Application Information

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