Fresh shaddock peel nanojuice, and preparation, lead-removing activity and application thereof

A technology of fresh grapefruit peels and grapefruit peels, which can be applied to medical preparations containing active ingredients, anti-toxins, plant raw materials, etc., and can solve the problems of no pharmacodynamic research

Inactive Publication Date: 2018-09-07
北京智诚拓展广告传媒有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In the absence of rigorous pharmacodynamic studies, these claims are based on experience only
F

Method used

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  • Fresh shaddock peel nanojuice, and preparation, lead-removing activity and application thereof
  • Fresh shaddock peel nanojuice, and preparation, lead-removing activity and application thereof
  • Fresh shaddock peel nanojuice, and preparation, lead-removing activity and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1 prepares fresh pomelo peel nano juice

[0024] 1000kg of fresh pomelo peels without silt on the surface are soaked in 3000kg-5000kg of tap water for 2 hours in a soaking pool. Afterwards, wash with 3000kg-5000kg water at least 3 times, filter out the water, and obtain clean fresh pomelo peels. Put the fresh pomelo peel washed with tap water into the water wave air-saturated washing machine, and then wash it with reverse osmosis purified water under the chain drive, and then enter the 300,000-class clean area through the transfer window. In the 300,000-level clean area, the grapefruit peels are sent to a centrifugal juicer for crushing and squeezing to obtain 1000±20kg of fresh grapefruit peel juice. Pack the original juice of fresh pomelo peel into barrels (10kg / barrel) and seal them. Pass the sealed fresh pomelo peel juice barrel (10kg / barrel) out of the clean area through the transfer window, and store it in a 5°C warehouse for use. The fresh pomelo pe...

Embodiment 2

[0025] Embodiment 2 measures the Tyndall effect of fresh pomelo peel juice

[0026] Place 5ml of fresh grapefruit peel juice in a colorless and transparent glass bottle, and irradiate the middle part of the fresh grapefruit peel juice with a laser pointer. A laser with a wavelength of 650nm makes a red light channel appear in the middle of the light yellow transparent fresh pomelo peel juice. It can be seen that fresh pomelo peel juice has Tyndall effect (see figure 1 ). Because the Tyndall effect is a characteristic of nano-solutions, the light yellow and transparent fresh grapefruit peel juice is a nano-solution. The nano-morphology of fresh pomelo peel juice is evidence that the preparation method of the present invention has obtained unexpected technical effects.

Embodiment 3

[0027] Example 3 Measure the average particle diameter of the nanoparticles of the components in the fresh pomelo peel juice

[0028] 2ml of fresh pomelo peel juice was placed in a dedicated measuring tank, and the average particle size was measured on a particle size analyzer (Nano-ZS90; Malvern Instruments Ltd, Malvern, UK) at 25°C. The results show that the average particle diameter of the nanoparticles formed by the components in the fresh pomelo peel juice is 704.0 ± 228.6nm (see figure 2 ). It can be seen that the particle size of the nanoparticles formed by the components in the fresh grapefruit peel juice is in the particle size range that is beneficial to the absorption and delivery of the human body. This is the unexpected technical effect evidence that the method for preparing fresh pomelo peel juice of the present invention obtains.

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PUM

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Abstract

The invention discloses a preparation method for fresh shaddock peel nanojuice, nanosolution properties of the fresh shaddock peel nanojuice, and the treatment effect of the fresh shaddock peel nanojuice on mice with lead poisoning. The invention also discloses application of the fresh shaddock peel nanojuice to preparation of drugs used for preventing and treating lead poisoning.

Description

field of invention [0001] The invention relates to a kind of fresh pomelo peel nano juice, its preparation method, its nano solution properties, and its therapeutic effect on lead poisoning mice. Therefore the present invention relates to its application in the preparation of medicines for the treatment and prevention of lead poisoning. The invention belongs to the field of biomedicine. Background technique [0002] Lead is widely related to people's daily work and life, and it is a heavy metal that can cause diseases to the human body. Lead can not only enter the human body through various channels, but also accumulate in the human body, causing damage to the human body. After lead enters the human body, it can compete with metal ions for binding sites with proteins, thereby affecting the normal physiological functions of the human body. Lead poisoning has a serious impact on human health, especially for developing children. Low levels of blood lead concentration in the...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61P39/02A61K131/00
CPCA61K36/752A61K2236/13A61K2236/31A61K2236/53
Inventor 彭师奇吴滨赵明
Owner 北京智诚拓展广告传媒有限公司
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