An osteogenic, rapidly absorbing hemostatic bone wax

A fast bone-promoting technology, applied in surgery, drug delivery, surgical adhesives, etc., can solve problems affecting bone fusion and residues, and achieve the effects of improving healing speed, rapid absorption, and increased absorption rate

Active Publication Date: 2021-05-25
中国人民解放军海军军医大学第一附属医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problem that the use of traditional bone wax in spinal surgery will produce residues that affect bone fusion, and the purpose is to provide a fast-absorbable hemostatic bone wax that has similar physical properties to traditional bone wax and promotes bone formation.

Method used

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Embodiment Construction

[0014] In order to make the technical means, creative features, goals and effects of the present invention easy to understand, the following examples specifically illustrate the composition, working principle and beneficial effects of the bone-promoting, rapidly absorbable hemostatic bone wax provided by the present invention.

[0015] In this embodiment, the preparation method of rapidly absorbable hemostatic bone wax that promotes bone formation is as follows: respectively weigh chitosan powder and poloxamer 407 powder of predetermined weight and mix evenly, and then weigh predetermined weight of poloxamer 188 solution and sodium hyaluronate powder, added to the mixed chitosan powder and poloxamer 407 powder, fully mixed, after obtaining the bone wax mixture, carry out high-pressure steam sterilization in a high-pressure steam sterilizer, and put it in an oven at 50 degrees Celsius after sterilization Dry and store in sterile glass dishes.

[0016] The raw materials in this ...

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Abstract

A rapidly absorbable hemostatic bone wax that promotes bone formation, used for hemostasis on the bone surface of the spine in spinal surgery, is characterized in that it comprises: a poloxamer mixture with a mass percentage of 60-75%; a mass percentage of 20-30% % chitosan; and 5‑20% sodium hyaluronate by mass.

Description

technical field [0001] The invention relates to a hemostatic bone wax, in particular to an absorbable hemostatic bone wax. Background technique [0002] As a commonly used hemostatic material, bone wax is widely used in orthopedics and neurosurgery. It is suitable for hemostasis on various cancellous bone wounds. It has good hemostatic effect and is easy to use. However, fracture healing is a complex and continuous process. During the hematoma organization period of the fracture, due to the injury caused by the fracture, blood vessels rupture, and hematoma forms around the fracture. After 24 hours, it begins to condense into a blood clot containing reticular cellulose, and after 24 hours, it begins to be organized and wrapped, and fibrous tissue proliferates. After very complicated fibrosis, fibrous callus begins to form at the fracture end in about 2 weeks. During this period, if there are foreign objects on the fracture surface (including its own soft tissue or absorbabl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L24/04A61L24/00
CPCA61L24/0042A61L24/043A61L2400/04C08L5/08C08L71/02
Inventor 王文涛何大为刘军沈禹航黄帅吴东桦
Owner 中国人民解放军海军军医大学第一附属医院
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