Optical tweezer device with adjustable beam intensity

Abstract

The invention discloses an optical tweezer device with adjustable beam intensity. The device includes a laser power, a laser and a microscope, wherein the laser power source is connected to the laser.Laser light emitted by the laser propagates to a first refractive plate through a part of an optical fiber, and is refracted by the first refractive plate to particles or cell chambers on an objective table to form a light screen in the particles or the cell chambers and to divide the particles or cell chambers into upper chambers and lower chambers. Laser light emitted by the laser propagates toa gradual change light transmitting plate via another part of the optical fiber, and propagates through the gradual change light transmitting plate to a second refractive plate arranged in a microscope lens barrel, is refracted to an objective lens by the second refractive plate, and converges in front of the objective lens into optical tweezers emitting to the particles or cell chambers on the objective table. The device has the advantages of simple structure, simple and practical operation of optical tweezers, low cost, adjustable capture distance and accurate capture of particles or cells.

Description

technical field [0001] The invention relates to the technical field of optical tweezers, in particular to an optical tweezers device with adjustable beam intensity. Background technique [0002] Since the emergence of optical tweezers technology, optical tweezers have been widely used in life sciences, medicine, physics, materials and nanoscience due to their non-contact and non-destructive manipulation of micro-nano-scale particles, and are considered to be the most ideal single molecule , Single cell, particle, micro-nano device manipulation technology. [0003] Optical tweezers mostly use continuous laser and long pulse laser. Compared with continuous laser and long pulse laser, femtosecond laser pulse has extremely short pulse width, high peak power and time and space resolution, and can accurately detect Control action energy. At present, the high repetition rate femtosecond laser can be used as the light source to achieve stable capture of red blood cells, white bloo...

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Problems solved by technology

[0004] Although the above-mentioned patent can adjust the intensity of the light beam of the optical tweezers, the structure is complex and the cost of the materials used is high, which is not conducive to the realization of

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