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Synergistic system of plant extracts with antibacterial activity

A system and compound technology, applied in the direction of organic active ingredients, antibacterial drugs, antifungal agents, etc., can solve problems such as poor bacteriostatic properties

Inactive Publication Date: 2019-04-05
黄泳华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Plants are rich in ingredients with antibacterial activity. For example, the inventors found in their preliminary tests that the acetone extract from the roots of Leutea avicennia Mozaff. in western Iran is sensitive to methicillin-sensitive Staphylococcus aureus and other common Human pathogenic bacteria have a certain antibacterial effect, but their antibacterial activity against methicillin-resistant Staphylococcus aureus is poor (not reaching IC 50 )

Method used

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  • Synergistic system of plant extracts with antibacterial activity
  • Synergistic system of plant extracts with antibacterial activity
  • Synergistic system of plant extracts with antibacterial activity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0132] Example 1 Preparation of tablets containing a combination system composed of the first 2-cyclopropyl-4-phenylquinoline compound and the second 2-cyclopropyl-4-phenylquinoline compound prescription

[0133]

[0134] Preparation

[0135] Take the combination system, diluent and lubricant in the prescribed amount, mix thoroughly, and compress into tablets to obtain the obtained product.

Embodiment 2

[0136] Example 2 Preparation of capsules containing a combination system composed of the first 2-cyclopropyl-4-phenylquinoline compound and the second 2-cyclopropyl-4-phenylquinoline compound prescription

[0137]

[0138] Preparation

[0139] Take the combination system, diluent and lubricant in the prescribed amount, mix them thoroughly, fill them into capsules, and get ready.

Embodiment 3

[0140] Example 3 Preparation of granules containing a combination system composed of the first 2-cyclopropyl-4-phenylquinoline compound and the second 2-cyclopropyl-4-phenylquinoline compound prescription

[0141]

[0142] Preparation

[0143] Take the combination system, diluent and lubricant in the prescribed amount, mix them thoroughly, and pack them separately to get the product.

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Abstract

The invention provides a combination system formed by 2-cyclopropyl-4-pheoylquinoline compounds. The combination system enhances the antibacterial effect of acetone extracts at the root parts of Leutea avicennia Mozaff through the synergistic effect.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and in particular relates to a combined system capable of enhancing the antibacterial effect of Leuteaavicennia Mozaff. extracts through synergistic action. Background technique [0002] Infectious diseases are a large class of diseases caused by microbial infections such as bacteria, parasites, fungi, or viruses, and can be transmitted directly or indirectly between humans through various channels. Although a variety of anti-infective drugs, including antibiotics, antivirals, antifungals, and antiparasitics, are currently available for the treatment of infectious diseases, this disease remains one of the leading causes of illness or death worldwide. In 2010, approximately 15 million people worldwide died from infectious diseases. [0003] Although the application of antibiotics and synthetic antibacterial drugs such as penicillins, cephalosporins, and quinolones has played a huge role in th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/47A61K31/4709A61P31/04A61P31/10A61P31/02A61K36/85
CPCA61K31/47A61K31/4709A61K36/85A61P31/02A61P31/04A61P31/10
Inventor 向飞萨拉肯特·L李斯匹朋·H
Owner 黄泳华
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