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Paper chip integrated with standard color bar

A standard ribbon and paper chip technology, which is applied in the direction of material analysis, measuring devices, instruments, etc. by observing the influence of chemical indicators, can solve the problems of individual chip differences and ambient light, and achieve the reduction of chip individual differences and ambient light Influence, fast and accurate detection of the effect

Inactive Publication Date: 2019-09-03
YANGTZE DELTA REGION INST OF TSINGHUA UNIV ZHEJIANG +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The visual inspection method is greatly affected by the subjective factors of the observer. After taking pictures and scanning, there is currently no standard color band in the detection. At the same time, take pictures and scans for comparison, there are errors caused by individual differences in chips and the influence of ambient light.

Method used

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  • Paper chip integrated with standard color bar
  • Paper chip integrated with standard color bar
  • Paper chip integrated with standard color bar

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1: A single index detection paper chip with integrated standard ribbon

[0023] Such as figure 1 As shown, a single-indicator detection paper chip integrated with a standard ribbon includes a substrate 1 on which a standard ribbon area 2 and a detection area 3 are set. The standard color band area 2 is composed of a color band 21 and a text label 23. The color band 21 has a number of color blocks 22 arranged linearly with gradients in color intensity, and the density is marked next to the corresponding color blocks 22. The color block 22 of the ribbon 21 is the same color as the corresponding index to be measured after color reaction, and the number of the color block 22 is adjusted according to the concentration range and precision of the index to be measured, and is 3-20. The pattern formed by each color block 22 on the substrate 1 is strip-shaped or dot-shaped, and the pattern width or diameter of each color block 22 is 0.1-10 mm. The detection area 3 inclu...

Embodiment 2

[0025] Example 2: A dual-index detection paper chip with integrated standard ribbon

[0026] Such as figure 2 As shown, a dual-indicator detection paper chip integrated with a standard ribbon includes a substrate 1 on which a standard ribbon area 2 and a detection area 3 are set. The standard color band area 2 is composed of two color bands 21 and text labels 23, each color band 21 has a number of linearly arranged color blocks 22 with gradient changes in color intensity, and the concentration is marked next to the corresponding color block 22, each color Mark the name of the indicator next to band 21. The color block 22 of the ribbon 21 is the same color as the corresponding index to be measured after color reaction, and the number of the color block 22 is adjusted according to the concentration range and precision of the index to be measured, and is 3-20. The pattern formed by each color block 22 on the substrate 1 is strip-shaped or dot-shaped, and the pattern width or d...

Embodiment 3

[0028] Example 3: A single-index detection microfluidic paper chip with integrated standard ribbon

[0029] Such as image 3 As shown, a single-index detection microfluidic paper chip integrated with a standard ribbon includes a substrate 1 on which a standard ribbon zone 2 and a detection zone 3 are set. The standard color band area 2 is composed of a color band 21 and a text label 23. The color band 21 has a number of color blocks 22 arranged linearly with gradients in color intensity, and the density is marked next to the corresponding color blocks 22. The color block 22 of the ribbon 21 is the same color as the corresponding index to be measured after color reaction, and the number of the color block 22 is adjusted according to the concentration range and precision of the index to be measured, and is 3-20. The pattern formed by each color block 22 on the substrate is strip-shaped or dot-shaped, and the pattern width or diameter of each color block 22 is 0.1-10 mm. The de...

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PUM

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Abstract

The invention provides a paper chip integrated with a standard color bar. The paper chip comprises a standard color bar zone and a detection zone. The standard color bar zone includes color bars and text labels; each color bar is provided with a plurality of color blocks that are arranged linearly and have the color intensities changing in a gradient manner; and concentrations are marked beside the corresponding color blocks. The detection zone includes a color developing area. According to the provided paper chip, the standard color bar is integrated automatically and color developing area-standard color bar comparison is performed in detection each time. The paper chip is connected with supporting portable equipment. Therefore, the individual difference and ambient light influences in color comparison detection can be reduced; the rapid and accurate detection can be realized; and the visual observation of the color comparison detection observation experiment result is realized.

Description

technical field [0001] The invention relates to the technical field of paper chips, in particular to a paper chip integrated with a standard ribbon. Background technique [0002] Paper-based Microfluidics is a brand-new technology that only appeared in 2007. This technology uses paper (paper materials in a broad sense such as filter paper, chromatography paper, and nitrocellulose membrane) as a chip manufacturing material and a biochemical analysis platform. . The paper chip has the advantages of simple manufacturing method, low cost, small size, light weight, convenient storage and transportation, good biocompatibility, low sample / reagent consumption, fast analysis speed, simple follow-up processing, and its own porous structure can realize sample transportation without Advantages such as external driving force. It has good application prospects in medical diagnosis, environmental monitoring, food hygiene and other fields. [0003] Colorimetric detection is the most comm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/78
CPCG01N21/77G01N21/78G01N2021/7759
Inventor 叶嘉明高丽娟王晓东
Owner YANGTZE DELTA REGION INST OF TSINGHUA UNIV ZHEJIANG
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