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A micro-upgraded passive mixing mixer

A mixing type and mixer technology, applied in the direction of mixers, chemical instruments and methods, dissolution, etc., can solve the problems of large delay dead volume, low mixing uniformity, insufficient sealing performance, etc., to increase the contact area and improve the mixing Efficiency, jet effect enhanced effect

Active Publication Date: 2022-01-04
BEIJING SATELLITE MFG FACTORY
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Problems solved by technology

[0005] The technical problem to be solved by the present invention is to provide a micro-upgraded passive mixing type mixing machine to overcome the problems of large system delay dead volume caused by the large volume of the existing mixer itself, low mixing efficiency, low mixing uniformity, and insufficient sealing performance under high pressure. Applicable to food safety, pharmaceutical preparation, environmental protection testing, chemical engineering, scientific research, etc., using ultra-high pressure binary pump gradient elution method to achieve ultra-high performance liquid chromatography analysis

Method used

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  • A micro-upgraded passive mixing mixer
  • A micro-upgraded passive mixing mixer
  • A micro-upgraded passive mixing mixer

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Embodiment Construction

[0027] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0028] figure 1 It is a flow diagram of a high-precision ultra-high pressure liquid chromatography analysis system. The two mobile phases enter the port of the mixer through the check valve, the main cylinder, the pressure sensor, the auxiliary cylinder and the pressure sensor respectively. The two-phase fluid is mixed in the mixer and then output To the chromatographic column, the components and concentrations contained in the sample can be obtained through the detection and analysis system.

[0029] image 3 Structural diagram of micro-upgraded passive mixer for high-precision ultra-high pressure liquid phase pump. A micro-upgraded passive mixing mixer includes inlet end cover 1, inlet filter pad 2, inlet filter pad 1 3, inlet filter pad base 4, collar 2 5, collar 1 6, mixing particles 7, outlet filter Pad 8, mixing chamber 9, ou...

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Abstract

A micro-upgraded passive mixing mixer, comprising an inlet end cover (1), a mixing chamber assembly, an ultra-high pressure sealing structure assembly, and an outlet end cover (10); one end of the inlet end cover (1) is symmetrically arranged with solvent inlet holes, The ends of the solvent inlet holes converge to form an outlet hole that communicates with the other end face of the inlet end cover (1); the mixing chamber assembly and the ultra-high pressure sealing structure assembly are sequentially loaded into the inner cavity of the outlet end cover (10), and the inlet end cover (1) ) into the outlet end cover (10), and press the ultra-high pressure sealing structure assembly and the mixing chamber (9). The present invention overcomes the problems of large system delay dead volume, low mixing efficiency, low mixing uniformity, and insufficient sealing performance under high pressure caused by the large volume of the existing mixer itself, and is suitable for food safety, pharmaceutical preparation, environmental protection detection, chemical engineering, scientific research, etc. UHPLC analysis was realized by ultrahigh pressure binary pump gradient elution method.

Description

technical field [0001] The present invention relates to a passive mixer. Background technique [0002] The high-precision ultra-high pressure liquid phase pump (UHPLC) is developed on the basis of the high-performance liquid chromatography pump (HPLC). The stationary phase and high-efficiency chromatographic column used in it can increase the pressure at the output end of the pump to 150MPa, and the sample analysis The time is shortened from 10min-30min by HPLC to 40s-2min, which greatly shortens the sample analysis time, and its high sensitivity can effectively reduce cross-contamination. The fields of medicine, biochemistry, and food analysis have a wide range of application requirements for UHPLC. The mixer is a key component in the UHPLC system. The mixer is uniform, stable, high-sensitivity, and well-tight under ultra-high pressure. The mixer is the basis for obtaining high-resolution and high-sensitivity chromatographic analysis results. UHPLC requires When the two-p...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01F33/82B01F35/50B01F101/23
CPCB01F33/30352B01F35/00B01F2035/351B01F2101/23
Inventor 徐迎丽殷参范洪涛周旭杨东升孙宏宇刘建峰邹丹
Owner BEIJING SATELLITE MFG FACTORY
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