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Application of diagnostic marker for detecting hepatocellular carcinoma and screening or auxiliary diagnosis products

A diagnostic marker and hepatocellular carcinoma technology, which is applied in the application field of detection of hepatocellular carcinoma diagnostic markers and screening or auxiliary diagnostic products, can solve the problems of expression level and related transformation research that have not been reported, and achieve good results. Diagnostic efficiency, the effect of improving diagnostic efficiency

Active Publication Date: 2020-06-19
THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIV
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

It is not difficult to find that the current research on Gremlin-1 mainly focuses on basic research such as molecular mechanism, and its expression level in the plasma of patients with hepatocellular carcinoma and its related transformation studies have not been reported yet.

Method used

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  • Application of diagnostic marker for detecting hepatocellular carcinoma and screening or auxiliary diagnosis products
  • Application of diagnostic marker for detecting hepatocellular carcinoma and screening or auxiliary diagnosis products
  • Application of diagnostic marker for detecting hepatocellular carcinoma and screening or auxiliary diagnosis products

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Embodiment Construction

[0031] The specific implementation content provided in the present invention should not be construed as a limitation of the present invention. According to the content of the invention disclosed in the present invention, those skilled in the art can make appropriate changes without departing from the content of the present invention. The present invention will be described in detail below with reference to the accompanying drawings and examples.

[0032] The application of the expression level of Gremlin-1 in the plasma of the present invention in the detection of diagnostic markers for hepatocellular carcinoma, wherein the expression of Gremlin-1 in the plasma in the tissue samples of hepatocellular carcinoma HCC is mainly located at the junction of the stroma-tumor place. The application of the expression level of Gremlin-1 in the plasma in the product of detecting the diagnostic markers of hepatocellular carcinoma also includes the application of the expression level of al...

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Abstract

The invention discloses an application of the expression level of Gremlin-1 in blood plasma in a product of a diagnostic marker for detecting hepatocellular carcinoma. The expression of the Gremlin-1in the blood plasma in a tissue specimen of the hepatocellular carcinoma HCC is mainly located at the interstitial-tumor junction. The invention further discloses application of the Gremlin-1 in the blood plasma in screening or auxiliary diagnosis of hepatocellular carcinoma products. By applying the technical scheme of the invention, a product such as a kit for detecting the diagnostic marker ofthe hepatocellular carcinoma can be designed, and a product for screening or assisting in diagnosing the hepatocellular carcinoma can also be designed, so that the diagnostic efficiency and the clinical transformation value are further improved.

Description

technical field [0001] The present invention relates to the application in the product of detecting the diagnostic marker of hepatocellular carcinoma, and the technology of the application in the product of screening or auxiliary diagnosis of hepatocellular carcinoma. Background technique [0002] Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in my country and even in the world. Although in recent years, with the continuous improvement of surgical technology, comprehensive treatment methods based on "surgical treatment" have been widely used clinically, which has significantly improved the overall treatment effect of hepatocellular carcinoma. However, the overall treatment effect is still not good, and there is a high rate of recurrence and metastasis after surgery. The reason is mainly due to the inability to timely and effectively treat patients with hepatocellular carcinoma. 60-70% of patients with hepatocellular carcinoma have entered the mid...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/574
CPCG01N33/57438G01N33/57476G01N33/57484
Inventor 杨扬覃伟王励刘炜
Owner THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIV
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