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34results about How to "High diagnostic efficiency" patented technology

Two-dimensional image and CT or MR image three-dimensional fusion method

ActiveCN106204511APrecise positioningRich informationImage enhancementImage analysisResource informationDimensional images three
The invention discloses a two-dimensional image and CR or MR image three-dimensional fusion method. The method comprises the steps that three-dimensional geometric structure information of a CT or MRI structure image is used for combining multi-angle two-dimensional images for human body three-dimensional target image reconstruction, and then target image and MR image three-dimensional multi-modal fusion is achieved. According to the three-dimensional medical image fusion technology, the purpose of two-dimensional image three-dimensional complex structure positioning is achieved, and more precise focus positioning is provided; in addition, the two-dimensional image and the CT or MR image are subjected to three-dimensional fusion, multi-modal image system construction is achieved, more abundant resource information is provided for clinical disease diagnosis, and the diagnostic efficiency is improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF XIAN JIAOTONG UNIV

Adaptive multi-site scanning imaging method based on deep learning and system thereof

The invention discloses an adaptive multi-site scanning imaging method based on deep learning and a system thereof. The method is applied to a multi-modal imaging device mainly based on the nuclear medicine, and comprises the following steps of step A, for multiple target sites of an imaging target object, conducting single-modal or multi-modal reconnaissance scanning imaging; step B, utilizing image analysis software based on a deep learning technology to analyze the reconnaissance scanning imaging data in step A, and combined with relevant prior information, detecting a local area which needs further focus imaging and quantifying importance or risks thereof; step C, based on the results of step B, selecting an optimized process and parameters to perform the next scanning. The adaptive multi-site scanning imaging method maximizes the image diagnostic value contributed by unit scanning time and / or a radiation dose, achieves optimized precision image inspection for individuals through multi-site scanning imaging application on tumors to improve the diagnostic performance, and has an important practical value.
Owner:ATOMICAL MEDICAL EQUIP FO SHAN LTD

Transformer winding fault diagnosis method based on wireless identification sensing

A transformer winding fault diagnosis method based on wireless identification sensing includes the following steps: collecting transformer winding vibration signals in a normal state and when a fault occurs; denoising the transformer winding vibration signals by using singular entropy, and randomly dividing the denoised transformer winding vibration signals in the normal state into two groups, where one group is training data, and the other group is original measurement data; using the denoised transformer winding vibration signals obtained when the fault occurs as original threshold data; reconstructing the original threshold data to obtain reconstructed threshold data, and obtaining a transformer winding residual error threshold when the fault occurs; and reconstructing the original measurement data to obtain reconstructed measurement data, obtaining corresponding residual error data, and comparing the residual error data with the residual error threshold, to implement fault diagnosis on the transformer winding. The present invention implements remote, wireless, and unmanned fault diagnosis on a transformer winding. The diagnosis efficiency is high, the workload of a maintenance person is reduced, and the running efficiency of a transformer is increased.
Owner:WUHAN UNIV

X-ray ct apparatus

An X-ray CT apparatus, wherein a drum type rotation frame is rotatably supported by a fixed circular frame so as to surround an outer surface of the drum type rotation frame through a plurality of bearings provided between an inner surface of the fixing circular frame and an outer surface of the drum type rotation frame, for example in ring-like configuration. When the drum type rotation frame receives a large centrifugal acceleration due to a high speed rotation, outside expansion of the drum type rotation frame can be constrained due to both the rigidity of the fixed frame and the rigidity of the plurality of bearings provided on the outer surface of the rotation frame, thereby to maintain the relative positions of the X-ray tube and the X-ray detector and prevent deterioration of reconstructed images.
Owner:TOSHIBA MEDICAL SYST CORP

Navigation method and system for lung biopsy bronchoscope

The invention relates to a navigation method and system for a lung biopsy bronchoscope. The method comprises the following steps: acquiring CT image data; inputting the CT image data into the trained deep learning pulmonary nodule recognition neural network model, and outputting to obtain pulmonary nodule data; performing endoscope image space three-dimensional model reconstruction on the CT image data by using a virtual endoscope technology, and performing focus marking in an endoscope image space three-dimensional model in combination with pulmonary nodule data; selecting a focus mark in the endoscope image space three-dimensional model, and performing operation path planning; and mapping the pose of the bronchoscope catheter from the actual physical coordinate system to an endoscope image space, and carrying out registration from the actual physical position space to the image space. Compared with the prior art, the invention has the advantages of integration of deep learning nodule diagnosis, CT reconstruction and virtual endoscope navigation, accurate positioning, high diagnosis efficiency and the like.
Owner:TONGJI UNIV

Biomarker and method for detecting HBV related hepatocellular carcinoma

The invention relates to the field of medical science, and provides a biomarker for hepatocellular carcinoma related detection, particularly a biomarker for detecting HBV related hepatocellular carcinoma. The biomarker comprises an insulin-like growth factor binding protein 7 (IGFBP7) and an alpha fetoprotein (AFP). A method for detecting hepatocellular carcinoma, based on the biomarker namely the IGFBP7 and the AFP, comprises a step of carrying out judgement by measuring a marker IGFBP7 gene promotor methylation level and detecting the sensitivity of the marker AFP for being combined with serum IGFBP7 gene promoter methylation. According to biomarker, the AFP is combined with the IGFBP7 gene promoter methylation, so that the traditional detection of single indexes is changed, and the efficiency of HCC diagnosis is increased.
Owner:SHANDONG UNIV QILU HOSPITAL

Artificial intelligence assisted prostate tumor early diagnosis method based on surface enhanced Raman spectroscopy

The invention discloses an artificial intelligence assisted prostate tumor early diagnosis method based on surface enhanced Raman spectroscopy. The method comprises the following steps of: collectinga serum sample; adopting a Raman spectrometer for detection; performing graphic analysis and data processing on an acquired Raman spectrum signal; selecting a biological tissue Raman spectrum concentration range of 400-1800cm<-1> for analysis, and preprocessing an original spectrum acquired by a spectrograph through Origin Pro 8 software, i.e. performing background reduction and spectrum area homogenization, drawing a serum average Raman spectrum, and then comparing changes and differences of related Raman characteristic peaks, thus finally obtaining a diagnosis result of prostate tumor earlydiagnosis. The method provided by the invention is higher in sensitivity and specificity, and unnecessary needle biopsy and missed diagnosis caused by an existing screening diagnosis method are reduced.
Owner:RENJI HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Peripheral blood methylation gene and IDH1 combined detection and diagnosis model for lung cancer

The invention discloses a peripheral blood methylation gene and IDH1 combined detection and diagnosis model for lung cancer. The invention provides application of methylated SHOX2 gene, methylated PTGER4 gene and IDH1 protein as markers in preparation of products for diagnosis or auxiliary diagnosis of lung cancer, and constructs a three-marker combined lung cancer diagnosis model. Experiments prove that: compared with an incorporated single factor, the diagnosis efficiency of the combined diagnosis model is remarkably enhanced. Therefore, the diagnosis efficiency of the lung cancer can be improved by combined detection blood markers.
Owner:CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI

Mycobacterium tuberculosis combined antigen for diagnosing pulmonary tuberculosis

The invention provides a combined antigen comprising three mycobacterium tuberculosis antigens and an application of the combined antigen to preparation of a reagent for diagnosing active tuberculosis. The combined antigen comprises Rv3871, Rv3876 and Rv3879. Corresponding antibody detection methods are established by the aid of the three antigens and used for detecting corresponding antibody levels in biological samples, and the three detected antibody levels are particularly higher in sputum smear negative / sputum culture positive tuberculosis patients. A pulmonary tuberculosis diagnosing method is established by the aid of the combined antigen, and a positive sample is defined in such a manner that antibody levels corresponding to two or more antigens reach a positive judgment value. Verification of a lot of clinical samples indicates that the diagnosing method has the high sensitivity and the high specificity for sputum smear positive / sputum culture positive, sputum smear negative / sputum culture positive and sputum smear negative / sputum culture negative tuberculosis patients.
Owner:ACADEMY OF MILITARY MEDICAL SCI +1

Ultra-small functional nanocluster, nanoprobe and preparation method and application of nanoprobe

The invention provides an ultra-small functional nanocluster. A nanoculster structure is formed by taking GSH as a template and chelating sulfydryl and carboxyl on the surface of GSH with Au atom andgadolinium Gd atom; two types of atoms are simultaneously coated in the nanoculster structure. The invention also provides an ultra-small functional nanoprobe with the surface modified by cNGR and a preparation method thereof. The ultra-small functional nanoprobe has the capability of specifically identifying tumor angiogenesis; the quantum confinement effect of the Au atom is used for generatingfluorescence and absorbing X-ray according to the adsorption coefficient, so that fluorescence imaging and CT imaging can be achieved; the Gd atom is used for shortening longitudinal relaxation time of free water protons and enhancing MR contrast ratio, so that the application of the ultra-small functional nanoprobe in the multimodal imaging of the tumor angiogenesis can be achieved. The preparednanoparticles are small in size being smaller than 10nm, high in biocompatibility and low in toxicity; through the application of modular assembly performance of the nano material, efficient synergy of multiple functions is achieved; the ultra-small functional nanoprobe is high in preparation yield and is suitable for large-batch production.
Owner:THE SECOND HOSPITAL OF TIANJIN MEDICAL UNIV

Colloidal gold lateral flow test strip for breast cancer detection and colloidal gold lateral flow test strip for simultaneously detecting breast cancer and cervical cancer

The invention provides a colloidal gold lateral flow test strip for breast cancer detection, a preparation method of the colloidal gold lateral flow test strip and a colloidal gold lateral flow test strip for simultaneously detecting breast cancer and cervical cancer and belongs to the technical field of immuno-chemical detection. The colloidal gold lateral test strip comprises a PVC bottom plate,a nitrocellulose film, a sample pad, a conjugate pad and an absorption pad, and can be used for detecting miRNA markers (miR-16 and miR-191) and protein markers (CA153 and CA125) of breast cancer. The invention further provides a colloidal gold lateral test strip for simultaneously detecting breast cancer and cervical cancer, which can overcome the interference (hybridization among components) ofa background signal to realize specific detection on two different types of tumor marker groups, including miRNA groups and protein, of the cervical cancer and breast cancer, and has the detection specificity of 100 percent.
Owner:ANHUI SCI & TECH UNIV

Diagnosis system for vehicular DC charging relay

The present invention provides a diagnosis system for vehicular DC charging relay, the system comprises a controller, two resistor clusters R1 and R2, and a switch S, wherein, two resistor clusters R1 and R2 are bridging in a serially connected way in between the DC charging high voltage cables of the vehicle, the resistor cluster R1 consists of two serially connected sub-resistors, and the controller is able to measure a voltage V1 at a common terminal of the two serially connected sub-resistors via a first voltage detection port, the resistor cluster R2 consists of two serially connected sub-resistors, and the controller is able to measure a voltage V2 at a common terminal of the two serially connected sub-resistors via a second voltage detection port, the controller is able to execute a diagnosis operation, and the diagnosis operation is based on the measurements of the voltages V1 and V2.
Owner:NIO CO LTD

GIS-based power equipment distributed multistage intelligent fault diagnosis system

The invention discloses a GIS-based power equipment distributed multistage intelligent fault diagnosis system, which comprises an information acquisition module for collecting the macroscopic operation characteristics and the insulation operation characteristics of the power equipment through an SCADA and insulation online monitoring system; an initial diagnosis analysis module which is used for searching the equipment abnormal variable X from a real-time database and then carrying out preliminary diagnosis by utilizing an intelligent fault diagnosis model to obtain a preliminary diagnosis result; a comprehensive diagnosis and analysis module which is used for searching the detected information of other equipment related to the abnormal variable X, and then performing comprehensive diagnosis by utilizing an expert system in combination with the preliminary diagnosis result; and a diagnosis result display module which is used for displaying the fault information in a power distributionnetwork GIS in real time and sending out an alarm signal. According to the system, the real-time state data of the power system can be effectively utilized, according to the steps of determining the node closest to the fault, determining whether the fault is the single-line grounding fault and determining the fault line, the detection and positioning of the single-line grounding fault line are realized, and the safe operation of the system is facilitated.
Owner:EXAMING & EXPERIMENTAL CENT OF ULTRAHIGH VOLTAGE POWER TRANSMISSION COMPANY CHINA SOUTHEN POWER GRID

Transformer winding fault diagnosis method based on wireless identification sensing

A transformer winding fault diagnosis method based on wireless identification sensing includes the following steps: collecting transformer winding vibration signals in a normal state and when a fault occurs; denoising the transformer winding vibration signals by using singular entropy, and randomly dividing the denoised transformer winding vibration signals in the normal state into two groups, where one group is training data, and the other group is original measurement data; using the denoised transformer winding vibration signals obtained when the fault occurs as original threshold data; reconstructing the original threshold data to obtain reconstructed threshold data, and obtaining a transformer winding residual error threshold when the fault occurs; and reconstructing the original measurement data to obtain reconstructed measurement data, obtaining corresponding residual error data, and comparing the residual error data with the residual error threshold, to implement fault diagnosis on the transformer winding. The present invention implements remote, wireless, and unmanned fault diagnosis on a transformer winding. The diagnosis efficiency is high, the workload of a maintenance person is reduced, and the running efficiency of a transformer is increased.
Owner:WUHAN UNIV

Application of combined gene in esophageal squamous carcinoma

The invention relates to the technical field of biological medicines, and discloses an application of a combined gene in preparation of a product for diagnosing esophageal squamous carcinoma. The combined gene comprises the following genes of a CCL20 gene, a GSTP1 gene, an HSPB1 gene, a KRT14 gene, a KRT15 gene, an S100A8 gene, an S100A9 gene and a TACSTD2 gene. The invention also discloses an application of the combined gene in preparation of a pharmaceutical composition for treating the esophageal squamous carcinoma. Compared with single gene expression detection of the esophageal squamous carcinoma in the prior art, the combined gene has higher specificity and higher diagnosis efficiency, can significantly improve the detection sensitivity and specificity, can accurately, conveniently and efficiently perform esophageal squamous carcinoma early diagnosis and large-scale screening, and fills up the blank of an existing diagnosis technology, so that effective treatment measures are provided for esophageal squamous carcinoma patients in time, and prognosis is improved.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Network diagnosis method, cloud intelligent robot, network device and private network

A network diagnosis method, a cloud intelligent robot, a network device and a private network, relate to the technical field of communications, and are used for solving the technical problems of having low diagnosis efficiency and leakage risk for a private network in the prior art. The method comprises: an cloud intelligent robot transmitting a network monitoring instruction to a network device in a private network; receiving operation information transmitted by the network device according to the network monitoring instruction; diagnosing the network device according to the operation information to obtain a diagnosis result; and initiating a network configuration information update of the private network according to the diagnosis result.
Owner:CLOUDMINDS SHANGHAI ROBOTICS CO LTD

Application of diagnostic marker for detecting hepatocellular carcinoma and screening or auxiliary diagnosis products

The invention discloses an application of the expression level of Gremlin-1 in blood plasma in a product of a diagnostic marker for detecting hepatocellular carcinoma. The expression of the Gremlin-1in the blood plasma in a tissue specimen of the hepatocellular carcinoma HCC is mainly located at the interstitial-tumor junction. The invention further discloses application of the Gremlin-1 in the blood plasma in screening or auxiliary diagnosis of hepatocellular carcinoma products. By applying the technical scheme of the invention, a product such as a kit for detecting the diagnostic marker ofthe hepatocellular carcinoma can be designed, and a product for screening or assisting in diagnosing the hepatocellular carcinoma can also be designed, so that the diagnostic efficiency and the clinical transformation value are further improved.
Owner:THE THIRD AFFILIATED HOSPITAL OF SUN YAT SEN UNIV

Diagnosis system for vehicular DC charging relay

The present invention provides a diagnosis system for vehicular DC charging relay, the system comprises a controller, two resistor clusters R1 and R2, and a switch S, wherein, two resistor clusters R1 and R2 are bridging in a serially connected way in between the DC charging high voltage cables of the vehicle, the resistor cluster R1 consists of two serially connected sub-resistors, and the controller is able to measure a voltage V1 at a common terminal of the two serially connected sub-resistors via a first voltage detection port, the resistor cluster R2 consists of two serially connected sub-resistors, and the controller is able to measure a voltage V2 at a common terminal of the two serially connected sub-resistors via a second voltage detection port, the controller is able to execute a diagnosis operation, and the diagnosis operation is based on the measurements of the voltages V1 and V2.
Owner:NIO CO LTD

MiRNA marker for diagnosis and treatment of melanoma and related product thereof

The invention discloses a miRNA marker for diagnosis and treatment of melanoma and a related product thereof. The miRNA marker is a combination of miR-450a and miR-675. The product for diagnosis of the melanoma comprises a chip, a kit and a preparation, wherein the chip, the kit and the preparation comprise a probe for specifically recognizing the miR-450a and the miR-675 or a primer, probe or chip for specifically combining the miR-450a and the miR-675. According to the miRNA marker and the related product thereof, experimental verification shows that the miRNA marker has better diagnosis efficiency, and the combination of the miR-450a and the miR-675 has a synergistic effect, so that the miRNA marker and the related product thereof can be used for diagnosing and treating the melanoma.
Owner:北京百奥思科生物医学技术有限公司

Auxiliary diagnostic reagent for bronchial asthma

The invention discloses an auxiliary diagnostic reagent for bronchial asthma. The reagent for detecting proline is applied to preparation of an auxiliary diagnostic reagent for bronchial asthma. The invention also discloses application of the reagent for extracting and detecting proline in preparation of the auxiliary diagnostic reagent for bronchial asthma. The auxiliary diagnostic reagent for bronchial asthma comprises a reagent for extracting proline from serum and a reagent for quantitatively detecting proline. It is found for the first time that the plasma proline level of an asthma patient is higher than that of a normal person, and statistical significance is achieved. When the cutoff value of proline is 38.7 ug / mL, the area under an ROC curve for diagnosing asthma is 0.951 (P is less than 0.0001), which indicates that the diagnosis efficiency is relatively high. Plasma proline is used as a biomarker, a specimen is easy to take, alveolar lavage is not needed, the method belongs to noninvasive examination, early diagnosis of asthma can be assisted, a proline detection method is economical and easy to carry out, and a potential target spot is provided for diagnosis and treatment of bronchial asthma.
Owner:JIANGSU PROVINCE HOSPITAL THE FIRST AFFILIATED HOSPITAL WITH NANJING MEDICAL UNIV

Application of protein markers in combination in diagnosis of type 2 diabetes mellitus and type 2 diabetic nephropathy

The invention discloses an application of protein markers in combination in diagnosis of type 2 diabetes mellitus and type 2 diabetic nephropathy. The protein markers are Cathepsin D, alpha2-Macroglobulin and CD324. The protein markers can be jointly used for diagnosing and distinguishing healthy people from type 2 diabetic patients, diagnosing and distinguishing healthy people from type 2 diabetic nephropathy patients, diagnosing and distinguishing type 2 diabetic patients from type 2 diabetic nephropathy late patients, and diagnosing and distinguishing type 2 diabetic nephropathy early patients from type 2 diabetic nephropathy late patients, and is high in diagnosis efficiency. The protein markers have a prospect of being developed into a kit for diagnosing type 2 diabetes and type 2 diabetic nephropathy.
Owner:JIANGSU PROVINCIAL HOSPITAL OF TCM

Rifampicin drug-resistant tuberculosis molecular marker, detection reagent and application thereof

The invention provides a rifampicin drug-resistant tuberculosis molecular marker, a rifampicin drug-resistant tuberculosis detection reagent and application thereof, and relates to the technical field of biomedicine. The molecular marker comprises a TRIM9 gene, a TRIM21 gene, a TRIM56 gene and expression products of the TRIM9 gene, the TRIM21 gene and the TRIM56 gene. The expression of the TRIM9, TRIM21 and TRIM56 genes in a rifampicin drug-resistant tuberculosis patient is reduced. The rifampicin drug-resistant tuberculosis molecular marker can be used for identifying rifampicin drug-resistant tuberculosis patients more quickly, efficiently and sensitively, and can be used for screening rifampicin drug-resistant tuberculosis.
Owner:BEIJING CHEST HOSPITAL CAPITAL MEDICAL UNIV +1

Method for assisting determination of type iii hyperlipidemia

Disclosed is a method of distinguishing type III hyperlipidemia in the WHO-classified hyperlipidemia types (hereinafter referred to as type III) from other types of hyperlipidemia, which is a simpler method and has a higher diagnostic efficiency than conventional methods. The method of assisting the determination of type III hyperlipidemia includes the steps of: measuring the apoB-48 value, TG value and LDL-C value in a blood sample isolated from a living body; and calculating a ratio of the apoB-48 value divided by the TG value and a ratio of the apoB-48 value divided by the LDL-C value. In cases where both the ratio of the apoB-48 value divided by the TG value and the ratio of the apoB-48 value divided by the LDL-C value are higher than the respective cut-off values, it indicates that the living body is likely to have type III hyperlipidemia.
Owner:OSAKA UNIV +1
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