Parasite prevention and treatment agent for external use of animals, and preparation method
A biological control agent and parasite technology, applied to non-active ingredient medical preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problem of ineffective insect eggs, unclean deworming, high price, etc. problem, to achieve the effect of good insecticidal effect, high insecticidal activity, and quick effect
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[0037] The present invention also provides a preparation method of the above-mentioned external parasite control agent for animals, comprising the following steps:
[0038] (1), the following components are provided by weight percentage: 5-15% of fiprenil; 1-5% of bifenthrin; 1.5-4% of pyriproxyfen; 1.5-5% of dinotefuran; 4-10%; antioxidant 0.01-0.5%; main solvent 25-35%; co-solvent amount.
[0039] (2), using the main solvent to completely dissolve the fiprenil, the bifenthrin, the pyriproxyfen and the dinotefuran respectively.
[0040] (3) Using an appropriate amount of co-solvent to dissolve the antioxidant.
[0041] (4) Mix the dissolved fiprenil, the bifenthrin, the pyriproxyfen, the dinotefuran, the antioxidant and the crystallization inhibitor and stir thoroughly.
[0042] (5) Add the co-solvent to 100%, fully stir, and filter to obtain the parasite control agent for external use on animals.
[0043] The external parasite control agent for animals can be a spray or a...
Embodiment 1
[0046] The formulation and preparation method of animal external parasite control agent provided by the present invention are as follows (1L):
[0047] (1), the following components are provided by weight percentage: 10% of fiprenil, i.e. 100g; 3% of bifenthrin, i.e. 30g; 1.8% of pyriproxyfen, i.e. 18g; 2% of dinotefuran, i.e. 20g ; PEG-200 5%, that is 50ml; BHT0.1%, that is 1g; BHA0.2%, that is 2g; ethyl lactate 3.6%, that is 36ml; N-methylpyrrolidone 28%, that is 280ml; diethylene glycol Proper amount of ether.
[0048] (2), measure 200ml N-methylpyrrolidone to dissolve all of the described fiprenil, fully stir until completely dissolved, and become a pale yellow solution; measure 60ml of N-methylpyrrolidone to dissolve all of the described flumethrin, Stir fully until pyriproxyfen is completely dissolved and becomes a colorless solution; measure 20ml of N-methylpyrrolidone to dissolve all of the dinotefuran, stir well, completely dissolve and become a colorless solution; u...
Embodiment 2
[0053] The formulation and preparation method of animal external parasite control agent provided by the present invention are as follows (1L):
[0054] (1), the following components are provided by weight percentage: fiprenil 5%, i.e. 50g; bifenthrin 3%, i.e. 30g; pyriproxyfen 1.8%, i.e. 18g; dinotefuran 2%, i.e. 20g %; PEG-200 5%, that is 50ml; BHT0.1%, that is 1g; BHA0.2%, that is 2g; ethyl lactate 3.6%, that is 36ml; N-methylpyrrolidone 18.7%, that is 187ml; Proper amount of alcohol ether.
[0055] (2), take methylpyrrolidone to dissolve all of the fiprenil, the bifenthrin, pyriproxyfen and the dinotefuran respectively, and fully stir until completely dissolved; use all of the ethyl lactate Dissolve all the pyriproxyfen in the ester, stir well, dissolve completely, and present a colorless solution.
[0056] (3) Take an appropriate amount of diethylene glycol ether to completely dissolve all the BHT and BHA, and fully stir to form a colorless solution.
[0057] (4) Mix th...
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