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Method and system for evaluating cardiotoxicity of immune checkpoint inhibitor, and device

A technology of immune checkpoints and cardiotoxicity, applied in health index calculation, medical informatics, informatics, etc., can solve problems such as lack of, easy to miss low-risk patients, lack of scientific understanding of cardiovascular risk, etc.

Inactive Publication Date: 2020-09-25
ZHONGSHAN HOSPITAL FUDAN UNIV
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Problems solved by technology

[0004] At present, patients receiving immune checkpoint inhibitor therapy mainly seek cardiology consultation for cardiovascular events during treatment, and low-risk patients are easily missed
However, there is currently a lack of a concise predictive scoring system for the cardiovascular practice risk of patients receiving immune checkpoint inhibitor therapy, and there is also a lack of scientific understanding of the actual cardiovascular risk level of patients receiving immune checkpoint inhibitor therapy

Method used

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  • Method and system for evaluating cardiotoxicity of immune checkpoint inhibitor, and device
  • Method and system for evaluating cardiotoxicity of immune checkpoint inhibitor, and device
  • Method and system for evaluating cardiotoxicity of immune checkpoint inhibitor, and device

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Embodiment Construction

[0046] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention. ,

[0047] In the following description, references to "some embodiments" describe a subset of all possible embodiments, but it is understood that "some embodiments" may be the same subset or a different subset of all possible embodiments, and Can be combined with each other without conflict.

[0048] If there is a similar description of "first / second" in the application documents, add the following explanation. In the following description, the terms "first\second\...

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Abstract

The invention provides a method and a system for evaluating cardiotoxicity of an immune checkpoint inhibitor, and a storage device. In the prior art, oncology department doctors and surgeons cannot clearly determine the risk of cardiovascular disease complications, and early clinical manifestations of CVD are easily ignored, so that adverse clinical events caused by delayed treatment can be caused. A purpose of the invention is to solve the problem in the prior art. According to the invention, a risk assessment calculation method is adopted to assist a non-cardiologist to assess the risk of acardiovascular event, so that the non-cardiologist can be helped to quickly identify high-risk groups in the early stage, professional treatment suggestions are sought for the cardiac specialist, theoccurrence of the cardiovascular event can be reduced, and the severity of the event can be reduced.

Description

technical field [0001] The invention relates to the technical field of cardiovascular disease diagnosis, in particular to a method, device and equipment for assessing cardiotoxicity of immune checkpoint inhibitors. Background technique [0002] Cardiovascular disease (CVD) was previously considered to be a common disease and a major cause of death threatening human health. Although cardiology and oncology are generally considered to be separate disciplines, cardiotoxicity induced by many antineoplastic drugs has been extensively studied, and specific guidelines have made clear recommendations on this issue. However, the cardiotoxicity of immunotherapy has been rarely reported and has not attracted enough attention. With the continuous application of immune checkpoint inhibitor drugs, the cardiotoxicity caused by them is becoming more and more common. [0003] The mechanism by which immune checkpoint inhibitors induce cardiotoxicity is still unclear. According to existing s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/30G16H10/20
CPCG16H50/30G16H10/20
Inventor 程蕾蕾王妍陈佳慧林瑾仪吴薇李静王春晖张晨璐葛均波
Owner ZHONGSHAN HOSPITAL FUDAN UNIV
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