Method and system for evaluating cardiotoxicity of immune checkpoint inhibitor, and device

A technology of immune checkpoints and cardiotoxicity, applied in health index calculation, medical informatics, informatics, etc., can solve problems such as lack of, easy to miss low-risk patients, lack of scientific understanding of cardiovascular risk, etc.

CN111710425AInactive Publication Date: 2020-09-25ZHONGSHAN HOSPITAL FUDAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2020-09-25
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a method and a system for evaluating cardiotoxicity of an immune checkpoint inhibitor, and a storage device. In the prior art, oncology department doctors and surgeons cannot clearly determine the risk of cardiovascular disease complications, and early clinical manifestations of CVD are easily ignored, so that adverse clinical events caused by delayed treatment can be caused. A purpose of the invention is to solve the problem in the prior art. According to the invention, a risk assessment calculation method is adopted to assist a non-cardiologist to assess the risk of acardiovascular event, so that the non-cardiologist can be helped to quickly identify high-risk groups in the early stage, professional treatment suggestions are sought for the cardiac specialist, theoccurrence of the cardiovascular event can be reduced, and the severity of the event can be reduced.
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Description

technical field

[0001] The invention relates to the technical field of cardiovascular disease diagnosis, in particular to a method, device and equipment for assessing cardiotoxicity of immune checkpoint inhibitors. Background technique

[0002] Cardiovascular disease (CVD) was previously considered to be a common disease and a major cause of death threatening human health. Although cardiology and oncology are generally considered to be separate disciplines, cardiotoxicity induced by many antineoplastic drugs has been extensively studied, and specific guidelines have made clear recommendations on this issue. However, the cardiotoxicity of immunotherapy has been rarely reported and has not attracted enough attention. With the continuous application of immune checkpoint inhibitor drugs, the cardiotoxicity caused by them is becoming more and more common.

[0003] The mechanism by which immune checkpoint inhibitors induce cardiotoxicity is still unclear. According to existing s...

Examples

Embodiment Construction

[0046] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention. ,

[0047] In the following description, references to "some embodiments" describe a subset of all possible embodiments, but it is understood that "some embodiments" may be the same subset or a different subset of all possible embodiments, and Can be combined with each other without conflict.

[0048] If there is a similar description of "first / second" in the application documents, add the following explanation. In the following description, the terms "first\second\...