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Preparation method of temperature-sensitive plasma active biogel and active biogel

A temperature-sensitive, plasma-based technology, applied in the field of medical materials, can solve problems such as the fluidity of plasma active water with limited depth of direct action of plasma, and achieve the effects of local continuous treatment of lesions, increasing concentration, and broadening the scope of medical applications.

Active Publication Date: 2020-12-04
XI AN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The present invention can realize the storage and precise transportation of plasma active particles, and at the same time realize the long-term slow-release treatment of active particles in the same lesion, which solves the problems of limited depth of direct action of plasma and fluidity of plasma active water, effectively Expanding the range of medical applications of plasma

Method used

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  • Preparation method of temperature-sensitive plasma active biogel and active biogel
  • Preparation method of temperature-sensitive plasma active biogel and active biogel
  • Preparation method of temperature-sensitive plasma active biogel and active biogel

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Embodiment Construction

[0027] The following will refer to the attached Figure 1 to Figure 3 Specific examples of the present invention are described in more detail. Although specific embodiments of the invention are shown in the drawings, it should be understood that the invention may be embodied in various forms and is not limited to the embodiments set forth herein. Rather, these embodiments are provided for more thorough understanding of the present invention and to fully convey the scope of the present invention to those skilled in the art.

[0028] It should be noted that certain terms are used in the specification and claims to refer to specific components. Those skilled in the art should understand that they may use different terms to refer to the same component. The specification and claims do not use differences in nouns as a way of distinguishing components, but use differences in functions of components as a criterion for distinguishing. "Includes" or "comprises" mentioned throughout ...

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Abstract

The invention discloses a preparation method of temperature-sensitive plasma active biogel and the active biogel. The preparation method comprises the following steps of mixing a biogel material witha solvent to prepare a temperature-sensitive biogel solution; activating the temperature-sensitive biogel solution by using a plasma device to prepare a temperature-sensitive plasma active biogel solution, wherein the temperature-sensitive plasma active biogel solution comprises plasma active particles; adjusting the temperature of the temperature-sensitive plasma active biogel solution to enablethe temperature to reach a phase change threshold value; and gelatinizing the temperature-sensitive plasma active biogel solution to be cured to be in a gel state so as to generate the temperature-sensitive plasma active biogel.

Description

technical field [0001] The invention relates to the technical field of medical materials, in particular to a method for preparing a temperature-sensitive plasma active biological glue and the active biological glue. Background technique [0002] Plasma is the fourth state of matter besides solid, liquid, and gas. Relevant studies have shown that in an atmospheric pressure environment, the atmospheric pressure-cooled plasma generated by discharge contains a rich variety of reactive nitrogen and reactive oxygen particles. These reactive particles play a role in many biomedical effects such as promoting wound healing and inducing cancer cell apoptosis. Key role. In recent years, atmospheric pressure-cooled plasma technology has been widely used in biomedical fields such as medical device sterilization, chronic wound healing, tissue ablation, and tumor treatment. Although plasma, as a new technology for efficiently generating exogenous active particles, has shown great potenti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K41/00A61K45/00A61K47/34A61L31/06A61L31/14A61P31/00A61B18/00A61P35/00
CPCA61K9/06A61K47/34A61K9/0014A61K9/0024A61K45/00A61K41/0004A61P35/00A61P31/00A61L31/06A61L31/14A61L31/145A61B18/00A61L2300/416A61L2300/404A61L2400/06A61B2018/00583
Inventor 张浩刘定新胥胜多张基珅
Owner XI AN JIAOTONG UNIV
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