Carrier for removing inflammatory factors in articular cavity effusion and releasing anti-inflammatory drugs

Abstract

The invention discloses a carrier for removing inflammatory factors in articular cavity effusion and releasing anti-inflammatory drugs. The carrier comprises a main body structure, the main body structure comprises a spherical outer wrapping layer and a central sphere, the spherical outer wrapping layer is uniformly provided with a plurality of through holes, the central sphere is wrapped in the spherical outer wrapping layer, the spherical outer wrapping layer is formed by a membrane made of phospholipid, the thickness of the spherical outer wrapping layer is 50-100 microns, the plurality of through holes are round through holes, the aperture of the plurality of through holes is 30-50 microns, and the central sphere is made of nano-scale anti-inflammatory drug particles. The carrier for removing the inflammatory factors in the articular cavity effusion and releasing the anti-inflammatory drugs can be metabolized and absorbed by a human body, can effectively remove the inflammatory factors in the articular cavity of the human body, can be used as the carrier to release and slowly release the anti-inflammatory drugs, and finally achieves the purposes of removing the inflammatory factors in the articular cavity and controlling local inflammation so as to controlthe illness state, and side effects can be avoided.

Description

technical field [0001] The invention relates to the technical field of medicine, more specifically, it relates to a carrier for removing inflammatory factors in joint cavity effusion and releasing anti-inflammatory drugs. Background technique [0002] Some disease factors (such as RA, osteoarthritis, trauma) will cause local joint effusion in patients, especially in the knee joint. Most patients have a large amount of effusion in the joint cavity, and it contains a variety of inflammatory factors , long-term existence will lead to aggravation of local inflammation or joint destruction. Clinically, extraction of intraarticular effusion and intracavitary injection of drugs are often used to treat patients. Intracavitary injection drugs are generally hormones (Diprosone), lubricants (sodium hyaluronate) and TNF-α antagonists, etc., but The hormones, lubricants, and TNF-α antagonists used above cannot be metabolized and absorbed by the human body. It is not only difficult to re...

AI Technical Summary

Problems solved by technology

Clinically, extraction of intraarticular effusion and intracavitary injection of drugs are often used to treat patients. Intracavitary injection drugs are generally hormones (Diprosone), lubricants (sodium hyaluronate) and TNF-α antagonists, etc., but The hormones, lubricants, and TNF-α antagonists used above cannot be metabolized and absorbed by the human body. Not only is it difficult to remove inflammatory factors in the human joint cavity, but it is also difficult to control local inflammation. The side effects are large, and ultimately it is difficult to control the patient's condition

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