Drug action mechanism analysis method and device and electronic equipment

A technology of mechanism analysis and drug action, applied in the computer field, can solve the problems of complex composition of traditional Chinese medicine, low efficiency of analysis of the mechanism of action of traditional Chinese medicine, and poor purpose.
CN113643751APending Publication Date: 2021-11-12TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
Publication Date
2021-11-12

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Abstract

The embodiment of the invention provides a drug action mechanism analysis method and device and electronic equipment, and relates to the technical field of computers. The method comprises the following steps: determining common gene targets related to a to-be-analyzed drug and a target disease treated by the to-be-analyzed drug; determining a target regulatory pathway between the gene targets in the common gene targets; constructing a first analysis network about the corresponding relationship among the target regulatory pathway, the common gene target and the target compound in the to-be-analyzed drug; and according to the common gene target represented by the first analysis network and the connectivity of the target compound in the to-be-analyzed drug, determining the effective components in the to-be-analyzed drug and the target gene target acted by the to-be-analyzed drug when the to-be-analyzed drug treats the target disease. Compared with the prior art, by applying the scheme provided by the embodiment of the invention, the action mechanism of the traditional Chinese medicine compound can be efficiently and systematically analyzed so as to comprehensively screen the effective components in the traditional Chinese medicine compound and the gene targets on which the effective components act.
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Description

technical field

[0001] The invention relates to the technical field of computers, in particular to a method, device and electronic equipment for analyzing the mechanism of drug action. Background technique

[0002] In the process of using Chinese medicine compound to treat diseases, the Chinese medicine compound exerts synergistic effects in various biological processes of treating diseases through the joint action of the included components. In order to better improve the therapeutic effect of traditional Chinese medicine compound, it is usually necessary to analyze the mechanism of action of traditional Chinese medicine compound.

[0003] Among them, traditional Chinese pharmacy usually adopts the methods of separation, identification and pharmacological evaluation when analyzing the mechanism of action of traditional Chinese medicine compound.

[0004] However, due to the complexity of the composition of the compound Chinese medicine, the above-mentioned traditional Chin...

Claims

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