A personal care composition comprising piperlongumine and process for producing the composition

A technology of pipeamide and personal care, which can be applied in the directions of oral care, pharmaceutical formulations, cosmetic preparations, etc., and can solve problems such as difficulties in personal care compositions

Active Publication Date: 2021-11-26
UNILEVER IP HLDG BV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, it is difficult to produce personal care compositi...

Method used

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  • A personal care composition comprising piperlongumine and process for producing the composition
  • A personal care composition comprising piperlongumine and process for producing the composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0086] By mixing water + sorbitol and then adding TiO to the mixture 2 , saccharin, PEG1500 and sodium fluoride to prepare a matrix composition. Then silicon dioxide and sodium carboxymethylcellulose are added.

[0087] In a separate container, add Piperamide to the polyol listed in Table 1. The mixture was heated to 65°C and the mixture was stirred. The resulting Piperamide premix is ​​added to the matrix composition.

Embodiment A

[0088] For Example A, Piperamide was added directly to the matrix composition.

[0089] Finally, silica, surfactants and other minor components are added.

[0090] The formula of embodiment is as shown in table 1:

[0091] Table 1

[0092]

[0093] *Added as a premix with Piperamide.

[0094] Ease of formulation is reported in Table 2.

[0095] Table 2

[0096] Example result 1 Gingerdiol is uniformly dispersed in toothpaste 2 Uniform dispersion of gingerdiol in toothpaste formulations 3 Gingerdiol is unevenly dispersed in toothpaste A Difficult to formulate, does not disperse

[0097] The results in Table 2 show that it is easier to formulate compositions with the examples according to the invention compared to the comparative examples.

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Abstract

A process for producing a personal care composition comprising piperlongumine the process comprising the following steps: i) adding piperlongumine to a polyol or a polyol mixture comprising less than 5 wt% of the polyol mixture of water, to form a piperlongumine pre-mix in the form of a suspension or solution; ii) adding the resulting suspension or solution to a liquid base composition.

Description

[0001] The present invention relates to personal care compositions, and more particularly to compositions for topical surface or oral application. Background technique [0002] Many products we consume have a negative impact on our teeth and mouth. For example, acidic drinks and sweets can cause tooth erosion by eroding the enamel that protects the outer covering of teeth. Sticky food can accumulate in the spaces between the teeth and in the area between the gums and the teeth. Without good oral hygiene, these can harden over time with the help of oral bacteria to form a film called plaque. Gingivitis is an inflammatory process of the gums caused by a buildup of plaque and / or bacteria. During gingivitis, the bacteria present in the plaque biofilm and their corresponding components interact with the gingival tissue. Gingivitis is a mild stage of periodontal disease, defined as reversible inflammation. It is believed that good oral hygiene practices, such as brushing teeth a...

Claims

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Application Information

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IPC IPC(8): A61K8/34A61K8/49A61Q11/00
CPCA61Q11/00A61K8/345A61K8/4926
Inventor S·戈尔丁D·T·利特尔伍德R·E·马里奥特R·斯金纳
Owner UNILEVER IP HLDG BV
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