109 results about "Oral application" patented technology

Provided is a solid preparation for oral application containing (a) gum tragacanth and (b) a polyphosphoric acid or salt thereof and constituted so that the polyphosphoric acid or salt thereof starts to dissolve firstly and the gum tragacanth starts to dissolve subsequently. The solid preparation for oral application according to the present invention has a high plaque formation inhibiting effect.

An oral application for snoring prevention which has a flattened tube with an unobstructed airway and ridges on the inferior surface for pulling the tongue forward out of the path of the airway while the superior surface of the tube follows closely the hard and soft palate. The tube is short and extends in the oral cavity or mouth to a location which will not cause a gag reflex.

A device for expanding the connective fatty tissue and correcting inverted nipples and improving symmetry of the human breast by the application of gentle suction generated by oral inhalation comprises a hollow dome constructed from a pliable but rigid polymer. A rim on the open end of the dome provides an air tight seal with the skin tissue surrounding the breast. Tubing connected to the top center of the hollow dome facilitates oral evacuation of the air surrounding the breast. A valve or clamp allows the applied vacuum to be maintained for a desired period and readily released when desired. Oral application of the vacuum prevents excessive vacuum or pressure from being applied to the breast or surrounding tissue.

Disclosed is a novel solid dosage unit, preferably in the form of a film or thin troche, containing at least one pharmaceutical agent, and its method of manufacture, which involves introduction of a fluid containing at least one non-volatile material, such as a polymeric film forming substance, a volatile carrier and at least one pharmaceutical agent into a depression or cavity comprising the major element of the packaging film for the finished dosage unit (s), and removing the volatile carrier from the cavity by exposure to radiant energy, whereby the remaining non-volatile residue comprises the desired dosage unit. The packaging film can be subsequently lidded by conventional sealing methods to produce packaged dosage units which are suitable for sublingual and other oral applications.

A composite liquid biphenyl dimethyl dicarboxylate and its emulsion and oil injections for intravenous injection, intramuscular injection, or oral application are disclosed. Said emulsion has high stability and low granularity. Said solution-type oil has slow releasing effect.

A slowly releasing huperzine for treating sanile dementia by oral application features that its active components are huperzine A and its humolog, or their salts or ester derivatives. Its advantages are slow release (more than 12 hr), and high curative effect and safety.

The invention provides a traditional Chinese medicine capsule (Commodity Name: Weishuning Capsule) used for curing acute and chronic gastric diseases and esophageal enteric diseases, in particular to a traditional Chinese medicine capsule used for treating digestive system diseases; the traditional Chinese medicine capsule can prevent digestive tract cancerization through long-term oral application. The traditional Chinese medicine capsule essentially comprises the components of cuttlebone, concha arcae, ginseng, goldenthread root, common aucklandia root, lilac, semen amomi, amomum cardamomum, rhizoma corydalis, largehead atractylode, spicebush root, bergamot, cinnamon, semen raphani, green tangerine peel, ventriculi galli mucosa, magnolia officinalis, hyacinth bletilla, asarum, areca, agalloch, burreed tuber, zedoary, rhubarb root, calcined concha ostreae, immature orange fruit and liquorice. Coarse powder and a concentrated solution are mixed according to certain proportion, stirred, dried, smashed and sieved to prepare the traditional Chinese medicine capsule; the traditional Chinese medicine capsule has good curative effect for treating varied gastrointestinal diseases including acute and chronic gastritis, gastrointestinal hemorrhage, gastric acid, stomach-ache and duodenal ulcer, superficial, atrophic and vesicant gastritis, colonitis, etc. The traditional Chinese medicine capsule has simple prescription and preparation technique, low cost and is applicable to people in countries and mountainous areas where doctors and medicines are insufficient.

The invention discloses a combination process of nicotinamide riboside and its derivative with pyrroloquinoline quinone and its sodium salt. The combination process includes: combining any two or three of or all of NR (nicotinamide riboside) (a chloride, or nicotinamide riboside), NMN (beta-nicotinamide mononucleotide), NADH (nicotinamide adenine dinucleotide) and PQQ (pyrroloquinoline quinone disodium salt) into a formulation for making foods, health foods, cosmetics or drugs; the formulation is injected into the human body in external application, oral application or injection manner to takeeffect. The nicotinamide riboside and its derivative function to defy age; the pyrroloquinoline quinone and its sodium salt have the like function and are functionally complementary to nicotinamide riboside; the nicotinamide riboside or its derivative is combined with pyrroloquinoline quinone or its sodium salt into a formulation for making products, such as food additives, health foods, cosmetics and drugs, thereby delaying human senility, maintaining beauty or treating diseases.

An oral application for snoring prevention which has a flattened tube with an unobstructed airway and ridges on the inferior surface for pulling the tongue forward out of the path of the airway while the superior surface of the tube follows closely the hard and soft palate. The tube is short and extends in the oral cavity or mouth to a location which will not cause a gag reflex.

Microphone placement for oral applications are disclosed herein. The assembly may be attached, adhered, or otherwise embedded into or upon a removable oral appliance to form a hearing aid assembly. Such an oral appliance may be a custom-made device which can enhance and / or optimize received audio signals for vibrational conduction to the user. Received audio signals may be processed to cancel acoustic echo such that undesired sounds received by one or more intra-buccal and / or extra-buccal microphones are eliminated or mitigated. Multiple microphones may be positioned throughout the user's mouth to enhance reception of audio signals from outside sources as well as from the user's own voice. For instance, one or more microphones may be placed in contact with the inner surface of the user's cheeks to detect outside audio signals as well as in direct contact with the user's tooth or teeth to receive the user's voice through vibrational detection.

An application of verbascum glycoside in preparing the medicines for treating cancers by oral application or injection is disclosed.

A slowly releasing huperzine for treating sanile dementia by oral application features that its active components are huperzine A and its humolog, or their salts or ester derivatives. Its advantages are slow release (more than 12 hr), and high curative effect and safety.

An aqueous composition for oral care application comprising solution of an amidobetaine of the following general Formula I is disclosed;in which R is an alkyl of coconut fatty acids, preferably hydrogenated coconut fatty acids, or a fatty acid mixture group which, on the average, corresponds to coconut fatty acids, wherein the solution has a solids content of 36% by weight, a pH of 4.5 to 6, an alkylamidopropyldimethyl amine content of not more than 0.1% by weight, and a free fatty acid content less than 0.5% by weight, sodium chloride content of 6.0% max and dimethylaminopropylamino betaine (from N,N-dimethyl amino propyl 1,3-diamine (DMAPA) and monochloroacetic acid) content of 30 ppm max, free sodium monochloroacetic acid content of 5 ppm max and free N,N-dimethylamino propyl 1,3-diamine content of 5.0 ppm max.

The invention provides an acaudina molpadioidea active peptide with blood glucose reducing activity. According to a method for preparing an oral solution from an acaudina molpadioidea blood glucose reducing peptide, acaudina molpadioidea is used as a raw material, and the acaudina molpadioidea active peptide can be prepared from the acaudina molpadioidea, so that the method is low in cost, green and environmentally friendly; oral application of the acaudina molpadioidea active peptide can assist in reduction of blood glucose, and the acaudina molpadioidea active peptide has an effect of assisting in reducing blood glucose; and the oral solution can be prepared from the acaudina molpadioidea blood glucose reducing peptide serving as an effective component, and has a good market prospect. The method for preparing the oral solution from the acaudina molpadioidea blood glucose reducing peptide is easy for preparation, high in controllability, easy to operate and implement and favorable forindustrial large-scale production, and has a wide application prospect and good economical benefits.

The present invention relates to the application of the realgar microorganism leaching solution in anti tumor medicine preparation. The realgar microorganism leaching solution is prepared according to the exposed microorganism treating method in patent 2006102000675. The realgar leaching solution in the present invention has a profound inhabiting effect in a plurality of cancer disease comprising cancer of the liver, gastric cancer, leukemia and lung cancer. In addition, the application quantity is in level of microgram. Furthermore, because the realgar microorganism leaching solution is a dissoluble medicine, therefore the medicine can be applied respectively or applied in combination with other drugs, or with pharmaceutical acceptable excipient. The medicine is easy to be produced as various kinds of preparations, which comprises guttate pills, aerosol, vinum, syrups, oral application liquid, injection and injectable powder.

The invention relates to a composition, in the form of a gel, comprising tranexamic acid for topical oral application to a tooth extraction site either before, during or after the tooth extraction to control dental bleeding, to treat or prevent alveolar osteitis, or to produce or maintain a blood clot. The composition may comprise additional components such as chlorhexidine, methyl cellulose, a sweetener, a flavouring agent (e.g. mint), and a preservative (e.g. potassium sorbate).

A medicine in the form of inclusion compound for treating the disease in central nerve system and inflammation by injection, oral application, or exterior application is prepared from borneol and hydroxypropyl-beta-cyclodextrin through dissolving borneol in organic solvent, adding it to the aqueous solution of hydroxyproply-beta-cyclodextrin, high-speed stirring, laying aside, drying, dissolving in water, ultra-filtering, millipore filtering and freeze drying.

The invention discloses a Chinese medicinal preparation for treating diabetes with hypertension, which comprises the following raw material medicaments in parts by weight: Chinese angelica, fried szechwan Chinaberry, raw rehmannia root, prepared rehmannia root, red peony root, chrysanthemum, bupleurum falcatum, apocynum venetum, hawthorn, spike, bee glue, pollen, yam, golden thread and Chinese wolfberry bark. The preparation comprises all preparation forms suitable for oral application, preferably pills. The preparation can be prepared into any common oral preparation form by the conventional Chinese medicinal preparation method, preferably pills, powder, tablets, capsules and oral solutions. The medicament has the functions of cooling blood and hemostasis, dispelling wind and heat from the body, removing stagnation, reducing blood pressure and the like, and is used for treating the diabetes with hypertension.

The present invention discloses certain derivatives of artemisinin and the active principles contained in Artemisia annua extracts with amino acids, peptides, and amino sugars, and isomers and salts thereof (formula I). The compounds of the present invention possess wide-spectrum antibacterial and antifungal biological activity suitable for topical or oral application for the treatment of infections and topical ailments in mammals, including acne, rosacea, topical wounds, infections, dandruff, skin disfigurements caused by infection, skin discoloration, age spots, wrinkles, excess facial oil, and veterinary problems including canine infections;

The present invention relates to a pharmaceutical composition for oral application comprising: i) an anthelmintic agent; ii) a first excipient having a porous structure with an inner surface of about 500 to 1500 m2 / g and a surface area according to BET of up to about 5000 m2 / g; as well as to a method of preparing such a composition.

A treatment method for pathologies in which increased levels of MMP production are implicated in pathogenesis. Examples of such pathologies include pterygium, kerataconus, and macular degeneration. Treatment is based on administration of cysteamine in therapeutically effective amounts. Treatment may be in one of several alternative forms, including eye drops and oral applications. Administration in the form of eye drops may be preferred for pathologies affecting the eyes.

The invention belongs to the field of biological medicaments and health-care products, and relates to application of L-arabinose in preventing obesity and reducing weight, in particular to the application of the L-arabinose. The application of the L-arabinose composition is that the composition can effectively prevent increase of fat index in a human body caused by a high-sugar, high-fat and high-cholesterol diet, reduce the large amount of fat having been accumulated in the human body and reduce the weight through oral application.

This invention relates to inducible release vehicle comprised of crosslinked carbohydrates or proteins and an active ingredient. The release is induced by an external stimulus, e.g. an enzyme such as amylase. Such a vehicle can particularly be used in an applications for preventing microbial decay or combating microbial infections. Other uses are for oral applications such as providing anti-caries or flavoring compounds and for pharmaceutical and / or nutraceutical applications.

A composition and method for oral application to mouth tissue to reduce the symptoms of herpes simplex virus infection, said composition comprising an anti-viral agent, an antioxidant agent, an analgesic agent and a flavorant.

A Chinese medicine in the form of powder for treating cardiovascular and cerebrovascular diseases, such as coronary heart disease, arrhythmia, and hypertension by oral application or nasal inhalation is prepared from 13 Chinese-medicinal materials including musk, ox gallstone, Chinese angelica root, chuan-xiong rhizome, etc. Its advantage is high curative effect up to 93% or more.

The invention relates to a bath or oral application of immune activate compound in the fish immunity, wherein the invention has the advantages that: said compound ISCOMs is used to bath immunity to improve the antibody level and improve the increment transformation ability of T-lymphocyte, to induce the immune protection; when in the same dosage, the antibody level is higher than non-adjuvant group and the ISM1312 group; and the ISCOMs used in oral can improve the antibody level and improve the increment transformation ability of T-lymphocyte, to induce the immune protection.

The present invention discloses certain derivatives of artemisinin and the active principles contained in Artemisia annua extracts with amino acids, peptides, and amino sugars and salts thereof (formula I). The compounds of the present invention possess wide-spectrum antibacterial and antifungal biological activity suitable for topical or oral application for the treatment of infections and topical ailments in mammals, including acne, rosacea, topical wounds, infections, dandruff, skin disfigurements caused by infection, skin discoloration, age spots, wrinkles, excess facial oil, and veterinary problems including canine infections;

The invention discloses a preparation method of ginkgo water. The product provided in the invention is prepared by: grinding ginkgo oil and talcum powder fully and uniformly, adding water, and conducting shaking, precipitation, as well as filtration. The method is characterized in that: the weight ratio of the ginkgo oil and the talcum powder to water ranges from 1:10 to 20:500. The product obtained in the invention has the advantages of simple preparation process and stable quality, thus providing people a ginkgo water product with the characteristics of convenient oral application, quick absorption, fast metabolism, easy absorption and efficacy display.

The invention provides use of 5,7-methoxy-3,4'-flavonol in resisting of respiratory tract inflammatory diseases and relates to application of the 5,7-methoxy-3,4'-flavonol in preparation of drugs forresisting the respiratory tract inflammatory diseases. According to the use, proven by a series of experiments, 7-methoxy-3,4'-flavonol has obvious inflammation resisting, oxidation resisting, tracheacontraction reaction resisting activity; absorption can be achieved through oral drug administration, a relatively high drug effect is displayed, the bioavailability is 10% to 25%, and the 7-methoxy-3,4'-flavonol can be prepared into oral application preparations, injections and inhalants. The 5,7-methoxy-3,4'-flavonol can replace glucocorticoid preparations and is applicable to various respiratory tract inflammatory diseases such as bronchial asthma, acute bronchitis, chronic obstructive pulmonary disease, acute / chronic lung injury and respiratory distress and pulmonary fibrosis.

The present invention relates to bioadhesive compositions for oral application, which comprise a curcuminoid substance as an active ingredient. The present invention also relates to method of using said bioadhesive composition for the prevention and treatment of periodontal diseases such as gingivitis and other periodontal diseases.