Application of Nifuroxazide in preparation of medicine for treating hepatocellular carcinoma

Abstract

The invention relates to the technical field of biological medicines, and particularly discloses application of Nifuroxazide in preparation of a medicine for treating hepatocellular carcinoma, and Nifuroxazide is combined with radiotherapy to effectively inhibit growth of hepatocellular carcinoma cells and effectively inhibit expression of PD-L1 in the cells. The Nifuroxazide provided by the invention can inhibit the expression of PD-L1, especially the expression of PD-L1 in hepatocellular carcinoma cells caused by radiotherapy, so that the therapeutic effect of radiotherapy on hepatocellular carcinoma is improved, and a new possibility is provided for the preparation of liver cancer therapeutic drugs.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to the use of Nifuroxazide in the preparation of drugs for treating hepatocellular carcinoma. Background technique [0002] Tumor is a major killer that endangers the health of our country. According to statistics, there will be 9.96 million cancer deaths in the world in 2020, among which the number of cancer deaths in China will reach 3 million, accounting for 30% of the total number of cancer deaths. The economic burden brought by its treatment and the negative impact on social development are becoming increasingly prominent. The annual medical expenses for cancer treatment in my country alone amount to hundreds of billions of yuan, but most cancer patients still cannot escape the fate of death. Therefore, the treatment of tumors is still a hot spot in the scientific community. Tumor has been listed as one of the major diseases that need to be addressed in the "National Med...

AI Technical Summary

Problems solved by technology

However, there is still a lot of room for improvement in its curative effect. How to improve the therapeutic effect of radiotherapy for HCC is a focus of attention.

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