Method and apparatus for assessing patient response to treatment

A patient-response technology, applied in character and pattern recognition, computer-aided medical procedures, genomics, etc., can solve problems such as difficult response to treatment

Pending Publication Date: 2022-06-03
KONINKLJIJKE PHILIPS NV
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

Therefore, monitoring a patient's response to their treatment can beco

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  • Method and apparatus for assessing patient response to treatment
  • Method and apparatus for assessing patient response to treatment
  • Method and apparatus for assessing patient response to treatment

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Embodiment Construction

[0090]Monitoring cancer patients' response to treatment can be accomplished using medical imaging equipment, such as MRI and CT. Although these methods have the advantage of providing tumor location, early changes in tumor volume are not always easy to assess because the resolution of medical imaging is often in the millimeter range. Another patented method for monitoring cancer treatment response can be by analyzing biomarkers such as circulating tumor DNA, samples in the patient's body such as blood or other bodily fluids, and tracking the occurrence of specific mutations during treatment. However, because tumors may harbor a variety of mutations, it is common to investigate broad panels covering many different mutations that may show different trends over time. As a result, monitoring a patient's response to their treatment can be very difficult.

[0091] In order to facilitate monitoring of patient response to cancer therapy, the following disclosure describes the present...

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Abstract

The invention relates to monitoring a patient's response to treatment. To facilitate monitoring a patient's response to a treatment, the invention provides a method to identify a set of trends in each of the genetic changes having similar genetic changes over time, and to analyze the sets to determine a patient's response to a treatment.

Description

technical field [0001] The present invention relates to monitoring a patient's response to cancer treatment, and in particular to a method, apparatus and system, computer program element and computer readable medium for monitoring a patient's response to cancer treatment. Background technique [0002] Oncologists often use images created from computed tomography (CT) and / or magnetic resonance imaging (MRI) scans to guide management and compare the tumor to what it was before treatment began, helping doctors assess a patient's response to treatment . Although these imaging methods have the advantage of providing the location and shape of the tumor (eg relative to other organs), it can be difficult to assess early changes in tumor volume because the resolution of medical imaging is often in the millimeter range. Monitoring cancer patients' response to treatment can also be accomplished by analyzing patient samples, such as liquid biopsies that include blood or other bodily fl...

Claims

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Application Information

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IPC IPC(8): G16B40/30G16H50/30G16B20/50G06K9/62
CPCG16B40/30G16B20/50G16H50/30G06F18/23G06F18/241
Inventor P·J·范德扎格W·F·J·维尔哈格
Owner KONINKLJIJKE PHILIPS NV
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