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Apparatus and method for analysing

A technology of analysis position and sample analysis, which is applied in the direction of analyzing materials, measuring devices, and using microwave means for material analysis, etc. It can solve problems such as interference measurement, analysis inaccuracy, and cavity inequalities, and achieve fast and reliable measurement. Effect

Inactive Publication Date: 2003-06-18
ASTRAZENECA AB
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

However, due to the different physical parameters of each cavity, such as tolerances, dimensions, surface finish, etc., the cavities are not equal
This fact also leads to the imprecision of the analysis
In addition, due to the vibration of the vibration table, it is easy to affect the rotation of the test disc.
Therefore, these vibrations interfere with the normally performed measurements

Method used

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  • Apparatus and method for analysing
  • Apparatus and method for analysing
  • Apparatus and method for analysing

Examples

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Embodiment Construction

[0037] Refer to attached figure 1 The route of a sample to be analyzed in a sample providing device is schematically indicated. A pharmaceutical sample in a solid dosage form such as a tablet arrives at a sample receiver 2 for further delivery to an analysis site in the sample providing device 1 . The sample receiver transports and arranges the sample in a sequential arrangement and then further feeds the sample into the sample providing device. The purpose of the providing means is to provide a sample to the analysis device 4 so that a test can be carried out on the sample. When the measurement for analysis is complete, the sample is expelled from the sample providing device.

[0038] In a preferred embodiment the sample receiver 2 is connected in-line to a tablet production line. exist figure 2 In the illustrated embodiment, a conveying line 2 a from the sheeting process represents the sample receiver 2 . The delivery line is connected to a delivery slot 21 in the samp...

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Abstract

The present invention relates to a sample presentation apparatus for use in analysing equipment for pharmaceutical products, for example solid dosage forms such as a tablet, a pellet or a capsule. The invention further relates to a method for presentation of samples to the analysing equipment. Samples are sequentially fed through at least one predetermined analysing position (6) wherein at least one measuring radiation beam irradiates the sample (14) when it is located in the analysing position characterised in that there is at least one two-piece means (9, 39) for temporarily fixing each sample at said analysing position (6), the two-piece means comprises a first and a second sample holding part arranged at the analysing position in which the two-piece means is adapted to move between: an open position wherein a sample is provided for analysis, and a closed fixing position wherein a sample is analysed.

Description

technical field [0001] The present invention relates to a sample providing device for use in the analysis of pharmaceutical products such as solid dosage form tablets, pellets or capsules. The invention also relates to a method of providing a sample to a sample providing device and its use. Background technique [0002] Non-invasive, non-destructive analysis of the whole tablet can be achieved by means of near-infrared (NIR) or Raman spectroscopy. The common feature of these two technologies is that they utilize light in the NIR wavelength range (700-2500 nanometers (nm), especially 700-1500nm), where the pharmaceutical tablets are basically relatively transparent (low molar absorbency). Thus, light in this range can penetrate compressed powders and tablets by several millimeters and information about the contents can be obtained from the interior of the tablet, not just from the surface. Measurements are performed on a solid dosage form such as a tablet, pellet or a caps...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/35G01N1/00G01N21/27G01N21/33G01N21/64G01N21/65G01N33/15G01N35/02
CPCG01N33/15G01N21/359G01N21/65G01N21/33G01N21/64
Inventor S·福勒斯塔K·伦德斯特伦G·厄斯特林
Owner ASTRAZENECA AB
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