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Medicine composition for curing tumor

A composition and medicine technology, applied in the application field of genistein in medicine, can solve the problems such as the treatment of tumors that have not been seen with genistein

Inactive Publication Date: 2004-10-13
SHANDONG SHENGBANG MEDICINE SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The Institute of Materia Medica of the Fourth Military Medical University in my country once proposed genistein API and its capsules as a new drug application for the prevention and treatment of osteoporosis, but so far there has been no report of genistein as a tumor treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Dissolve 100 grams of genistein and 250 mg of citric acid in 360 grams of polyethylene glycol 400, then add 40 grams of glycerin, mix well, pass through a 200-mesh sieve, and make pellets. 1000 capsules were prepared, and each capsule contained 100 mg of genistein.

Embodiment 2

[0039] Dissolve 50 grams of genistein and 250 mg of citric acid in 410 grams of polyethylene glycol 400, then add 40 grams of glycerin, mix well, pass through a 200-mesh sieve, and make pellets. 1000 capsules were prepared, and each capsule contained 50 mg of genistein.

Embodiment 3

[0041] Dissolve 75 grams of genistein and 250 mg of citric acid in 160 grams of polyethylene glycol 400, then add 15 grams of glycerin, mix well, pass through a 200-mesh sieve, and make pellets. 500 capsules were prepared, each containing 150 mg of genistein.

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PUM

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Abstract

The present invention relates to a medicine composition for curing tumor. Its composition includes (wt%) 2-30% of genistein, 0-4% of soybean aglycone, 0-1% of biochain and 65-98% of auxiliary material. The composition can be used as new medicine preparation cor curing tumor, and can be made into soft capsule, hard capsule, dripping pill and injection. The medicine composition has obvious action for inhibiting continuous cell line of mammary cancer, carcinoma of stomach and liver cancer, and can inhibit tumor metastasis, and it is safe and has no toxic side effect.

Description

Technical field: [0001] The invention relates to medicines for treating tumors, and more specifically relates to the application technology of genistein in medicine. Background technique: [0002] Genistein (chemical name: 4', 5, 7-trihydroxy isoflavone), belonging to isoflavone compounds, is a weak phytoestrogen, widely present in plant diets such as soybeans, various vegetables and fruits, The most abundant in soybeans. In recent years, research on the physiological and health effects of soybean isoflavones has attracted much attention. A large number of epidemiological, cell culture and animal experimental studies have confirmed that soybean isoflavones are related to the occurrence, development and treatment of tumors. [0003] Epidemiological studies have found that tumors such as colon cancer, breast cancer, and prostate cancer have obvious regional distribution. Comparing the traditional eating habits of eastern and western countries, it is suggested that the daily...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K9/20A61K9/48A61K31/7048A61P35/00
Inventor 柴象枢赵爱平陈立军厉坤
Owner SHANDONG SHENGBANG MEDICINE SCI & TECH
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