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Method of transdermal and transmucosal absorption of carbon dioxide and cosmetic method and therapeutic method

A carbon dioxide, mucosal absorption technology for cosmetic and therapeutic applications

Inactive Publication Date: 2006-03-22
NEOCHEMIR INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, even with such a composition, since the amount of carbon dioxide absorbed through the skin and through the mucous membrane is not much, it needs to be used continuously for a long time in order to obtain sufficient cosmetic and therapeutic effects.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] (Whitening test with gaseous carbon dioxide on the back of the hand where the auxiliary liquid is applied)

[0049] Using water as an absorption aid, the right hand of a 22-year-old female was placed in water at 36° C. for 5 minutes to moisten the hand. The left hand was kept as it was, and each hand was placed in a transparent vinyl bag with a length of 25 cm and a width of 20 cm, and the wrist was tied with a rubber band to keep it in a sealed state, and the air in it was sucked out. Insert the vinyl tube into the part where the rubber band of each vinyl bag is tied, and blow in the gaseous carbon dioxide in the carbon dioxide gas cylinder. The gaseous carbon dioxide makes the vinyl bag expand as much as possible, and the back of the right hand turns red quickly. , observed that the blood circulation was promoted without any change in the back of the left hand. After 20 minutes, I took off each vinyl bag, and found that after the redness on the back of the right hand...

Embodiment 2

[0051] (whitening test with carbon dioxide-containing external preparation on the back of the hand to which absorption aid liquid was applied)

[0052] [Preparation of Composition A for External Use Containing Carbon Dioxide]

[0053] According to Example 18 of JP-A-2000-319187, use 2.4 parts by weight of sodium bicarbonate, 2.0 parts by weight of sodium alginate, 2.0 parts by weight of sodium carboxymethyl starch, 2.0 parts by weight of sodium carboxymethylcellulose, purified water 91.6 parts by weight and 2.0 parts by weight of citric acid were used to prepare external composition A containing carbon dioxide.

[0054] [Whitening test on the back of the hand]

[0055] Using water as an absorption aid, the right hand of a 22-year-old female was placed in water at 36° C. for 5 minutes to moisten the hand. The left hand was left as it was, and 15 g of external composition A containing carbon dioxide was applied to the backs of both hands and left for 15 minutes. After removin...

Embodiment 3

[0057] (Whitening test with gaseous carbon dioxide on the back of the hand to lower the skin temperature)

[0058] The frozen cooling agent was wrapped in a towel and placed on the back of the right hand of a 22-year-old woman, and the whole body was cooled down to lower the skin temperature to 20°C. The left hand was kept as it was, and each hand was placed in a transparent vinyl bag with a length of 25 cm and a width of 20 cm, and the wrist was tied with a rubber band to keep it in a sealed state, and the air in it was sucked out. Insert a vinyl tube into the part where the rubber band of each vinyl bag is tied, and blow in the gaseous carbon dioxide in the carbon dioxide gas bottle. The gaseous carbon dioxide makes the vinyl bag expand as much as possible. It is found that the back of the right hand turns red quickly. Observe The phenomenon that the blood flow is promoted, but there is no change in the back of the left hand. After 20 minutes, I took off each vinyl bag, and...

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PUM

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Abstract

It is intended to provide a method whereby cosmetic and therapeutic effects of carbon dioxide absorbed transdermally and transmucosally can be conveniently and strongly obtained. In this method, a treatment for increasing the amount of the transdermally and transmucosally absorbed carbon dioxide is performed before or during the administration of carbon dioxide. More specifically speaking, this treatment comprises a adding a carbon dioxide absorption auxiliary containing at least one liquid for dissolving carbon dioxide selected from the group consisting of water, lipids and organic solvents to the skin or mucosa. Alternatively, the treatment comprises lowering the temperature of the skin or mucosa.

Description

technical field [0001] The present invention relates to a transdermal and transmucosal absorption method of carbon dioxide, and a cosmetic method and treatment method using the same. Background technique [0002] Carbonated springs are known to exhibit cosmetic and therapeutic effects. These effects are obtained through the absorption of carbon dioxide through the skin and through the mucous membranes. Therefore, in order to obtain these effects easily, artificial carbonated spring bath agents have been developed so that families can use them conveniently. However, due to the low concentration of carbon dioxide gas (Soo-hyun Wan et al., Research on Artificial Carbonated Hot Springs (No. 3 Report): Basic Issues in the Preparation of Artificial Carbonated Springs and the Influence of Scattered Carbon Dioxide Gas Concentration, Daily Temperature Medical Journal: 48:79-85, 1985), it is the current status that insufficient cosmetic effects and therapeutic effects can be obtained...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/00A61K8/19A61Q17/00A61P17/00A61Q19/00A61Q19/02A61Q19/06
CPCA61K33/00A61Q19/00A61K8/19A61Q19/06A61Q19/02A61P1/02A61P3/10A61P9/10A61P17/00A61P17/02A61P17/06A61P19/02A61P21/00A61P25/04
Inventor 田中雅也
Owner NEOCHEMIR INC