Jixuedai gel with action of promoting wound reunion, and prepn. thereof

A technology of wound healing and glycoside gel, which is applied in the field of asiaticoside gel and its preparation, to achieve the effect of large water content, no pollution to clothes, and good coupling

Inactive Publication Date: 2006-09-20
BEIJING YINKERUISI BIOLOGICAL PODUCTS RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After searching, the preparation gel is still a blank in China

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Example 1: 27.5g of asiaticosides, 8g of carbomer, 100g of glycerin, 1.5g of sorbic acid

[0034] Take carbomer, add 800ml of distilled water under constant stirring, and stir until the carbomer is fully hydrated, add glycerin, stir evenly, dissolve with 2g NaOH and add appropriate amount of distilled water, adjust the pH to near neutral, and make a blank gel; Dissolve the total glucosides and sorbic acid in an appropriate amount of ethanol, add the alcohol solution to the blank gel, add distilled water to the full amount, stir evenly, and make 1000g of gel.

Embodiment 2

[0035] Embodiment 2: asiaticoside 10g, carbomer 1g, glycerin 10g, sorbic acid 1.0g

[0036] Take carbomer, add 800ml of distilled water under constant stirring, and stir until the carbomer is fully hydrated, add glycerin, stir evenly, dissolve with 0.15g NaOH and add appropriate amount of distilled water, adjust the pH to near neutral, and make a blank gel; Dissolve centella glycosides and sorbic acid in an appropriate amount of ethanol, add the alcohol solution to the blank gel, add distilled water to the full amount, stir evenly, and make 1000g of gel.

Embodiment 3

[0037] Embodiment 3: asiaticoside 50g, carbomer 15g, glycerin 200g, sorbic acid 5.0g

[0038] Take carbomer, add 600ml of distilled water under constant stirring, and stir until the carbomer is fully hydrated, add glycerin, stir evenly, dissolve with 3g NaOH and add appropriate amount of distilled water, adjust the pH to near neutral, and make a blank gel; The total amount of centella glycosides and sorbic acid was dissolved in an appropriate amount of ethanol, and the alcohol solution was added to the blank gel, and 75% ethanol was added to the full amount, and stirred evenly to make 1000 g of gel.

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PUM

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Abstract

A gel of asiaticoside for promoting healing of wound and treating burn, wound, skin ulcer, scleroderma, etc is prepared from asiaticoside and proper auxiliary. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to an asiaticoside gel capable of promoting wound healing and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. technical background [0002] Trauma, surgical trauma, burns, keloids and scleroderma are clinically more common diseases, among which skin ulcers, keloids, scleroderma and skin amyloidosis lack satisfactory drug treatments. Today's people's pursuit of quality of life has increased the demand for drugs that can promote wound healing. And chemical drugs and biological preparations such as Asia saponin sodium ointment, Kang Ruibao gel, collagenase ointment, freeze-dried mouse epidermal growth factor, recombinant human epidermal growth factor derivatives for external use, recombinant bovine basic fibroblast growth factor, Bacillus subtilis Viable bacteria preparations are preparations for treating such diseases, but most of them are only for external use and have certain side e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/704A61K9/00A61P17/02
Inventor 张保献
Owner BEIJING YINKERUISI BIOLOGICAL PODUCTS RES INST
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