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Compositions with anisic acid and glycerides

a technology of anisic acid and glyceride, applied in the field of formulations, can solve the problems of allergic reactions and irritation, formulations need to be adequately protected, and affect and degrade easily, and achieve the effect of reducing the amount of preservative agents

Inactive Publication Date: 2007-08-28
JOHNSON & JOHNSON CONSUMER FRANCE SAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0013]In an alternative aspect, this invention concerns the use of a combination of anisic acid, or a salt thereof, or an ester thereof, and a C6-14 fatty acid monoglyceride as a preservative system. This invention also concerns the use of a combination of anisic acid, or a salt thereof, or an ester thereof, and a C6-14 fatty acid monoglyceride to lower the amount of preservative agents in formulations for topical use.

Problems solved by technology

A disadvantage of using such agents is that they may cause adverse effects such as allergic responses and irritation.
This is the reason why so far, cosmetic formulations that can be applied to sensitive skin types (such as, e.g. atopic skin, baby skin, sun alterated skin, allergenic skin) contain less preservatives and therefore are prone to become affected and degraded by microorganisms and moreover to become a source of microbiological contamination.
A limiting factor evidently is that the formulations need to be adequately protected.
However, this would result in the concentration of the preservative being too low to be effective, resulting in an unacceptable risk of the formulation becoming affected by microorganisms.
Certain formulation categories therefore are not easy to preserve.
The presence of certain ingredients in DHA containing formulations promotes decay of this active ingredient and compromises the stability of DHA-based self-tanning formulations.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example

[0070]

Self-tanning emulsionIngredients (INCI)% w / wAqua64.5805Ethylhexyl Salicylate10.00Dihydroxyacetone10.00Ethylhexyl Stearate5.00Sorbitol2.10Cyclohexasiloxane1.90Arachidyl Alcohol1.65Glyceryl Caprylate1.00Hydrogenated Palm Glycerides Citrate0.0255Behenyl Alcohol0.90Arachidyl Glucoside0.45PEG-100 Stearate0.75Glyceryl Stearate0.75Cetyl Alcohol0.50p-Anisic Acid0.20Disodium EDTA0.10Tocopherol0.087Sodium Hydroxide0.007TOTAL100.00

[0071]A first mixture containing the lipophilic components and a second mixture containing the water and water-compatible ingredients was made. Subsequently, the oil phase was added to the aqueous phase under intense stirring as to build an emulsion.

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Abstract

This invention relates to formulations containing a combination of anisic acid, or a salt thereof, or an ester thereof, and a C6-14 fatty acid monoglyceride and to the use of such combinations as a preservative system.

Description

FIELD OF THE INVENTION[0001]This invention relates to formulations containing a combination of anisic acid, or a salt thereof, or an ester thereof, and a C6-14 fatty acid monoglyceride and to the use of such combinations as a preservative system.BACKGROUND OF THE INVENTION[0002]Preservatives are ingredients that have anti-microbial activity that are frequently used in skincare or cosmetic products. Preservatives are aimed at protecting these products from decay or spoilage, so that these products are protected from decomposition and deterioration and remain stable for extended periods of time, in particular during the entire shelf-life of the products.[0003]A disadvantage of using such agents is that they may cause adverse effects such as allergic responses and irritation. Examples of preservatives that are less tolerated especially at increased concentration, are the parabens and phenoxyethanol.[0004]This is especially the case when applying cosmetic formulations containing preserv...

Claims

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Application Information

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Patent Type & Authority Patents(United States)
IPC IPC(8): A61K31/19A61K31/22A61K8/368A61K8/37A61Q19/00A61Q19/04
CPCA61K8/368A61K8/375A61Q19/005A61Q19/04A61K2800/524A61K2800/59
Inventor BARANGER, FLORENCEPORRACCHIA, JEAN FRANCOIS
Owner JOHNSON & JOHNSON CONSUMER FRANCE SAS
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