Capsule for treating atrophic gastritis and preparation method thereof

Abstract

The invention discloses a capsule for treating atrophic gastritis and a preparation method thereof. The capsule is mainly prepared from the following ingredients in parts by weight: 6 to 12 parts of gentianine, 5 to 10 parts of zinc polyanemine, 3 to 6 parts of betulin, 3 to 5 parts of isorhamnetin, 1 to 3 parts of fumarine, 0.5 to 0.8 part of pepsin, 1 to 3 parts of tetrahydrocoptisine, 0.8 to 1.6 parts of rheum emodin, 5 to 8 parts of hericium erinaceus polysaccharide, 0.5 to 1.5 parts of maytanprine, 2 to 3 parts of phycocyanobilin, 2.5 to 4.5 parts of catechinic acid, 0.3 to 0.6 part of phenyl alanine and 0.2 to 0.5 part of renieratene; the capsule also comprises auxiliary materials including 65 to 85 parts of diluting agents, 3 to 5 parts of disintegrants and 2 to 4 parts of lubricating agents. The capsule is prepared from various western medicine ingredients by a capsule preparation process, and has the effects of resisting the bacteria, diminishing inflammation, inhibiting the bacterial infection, restoring the injured gastric mucosa, enhancing the resistance of the gastric mucosa, enhancing the organism immunity and preventing the cell cancerization; the treatment effect on the atrophic gastritis is obvious; the preparation process is simple; the use is convenient; and good clinic popularization significance is realized.

Description

technical field

[0001] The invention relates to the technical field of medication for digestive diseases, in particular to a capsule for treating atrophic gastritis and a preparation method thereof. Background technique

[0002] With the improvement of people's living standards, the incidence of chronic gastritis is getting higher and higher with age, and some patients develop cancer. Chronic atrophic gastritis is a common disease, which refers to the atrophy and metaplasia of the gastric mucosa. Mucosal epithelium and gland atrophy, reduced number, gastric mucosa thinning, mucosal base layer thickening, or with pyloric glandular metaplasia and intestinal glandular metaplasia, often involving the cardia, accompanied by loss of G cells and decreased secretion of gastrin, can also be Involvement of the gastric body, with loss of the oxyntic glands, resulting in a decrease in gastric acid, pepsin, and endogenous factors, or a chronic digestive disorder characterized by dysplasi...

Examples

Embodiment 1

[0018] Embodiment 1: a kind of capsule for the treatment of atrophic gastritis, described capsule is mainly made up of the composition of following parts by weight: 6 parts of gentianine, 5 parts of dark russin, 3 parts of betulin, different mouse 3 parts of lisu, 1 part of pro-opiate, 0.5 part of pepsin; the capsule also includes auxiliary materials: 65 parts of diluent, 3 parts of disintegrant, and 2 parts of lubricant.

[0019] Wherein, the described Anem rosin is a compound extracted from the roots of Anem lingshui, and its preparation method is: cut the roots of Anem lingshui into 2mm thick slices, place them in an oven for drying, and set the temperature of the oven at 60°C to make them The water content is less than 3%, crushed and passed through a 20-mesh sieve, add 5 times the amount of water, heat to 100 ° C for 2 hours, extract the decoction liquid and filter, and then extract the filter residue twice according to the above operation, and then combine three times Co...

Embodiment 2

[0025] Embodiment 2: a kind of capsule for treating atrophic gastritis, described capsule is mainly made up of the following components by weight: 9 parts of gentianine, 7.5 parts of dark russin, 4.5 parts of betulin, and Isorhamna 4 parts of prime, 2 parts of protopine, 0.65 part of pepsin; The capsule also includes auxiliary materials: 75 parts of diluent, 4 parts of disintegrant, 3 parts of lubricant.

[0026]Wherein, the above-mentioned anem rosin is a compound extracted from the root of lingshui anem, and its preparation method is: cut the root of lingshui anem into 2.5mm thick slices, place it in an oven for drying, and set the temperature of the oven at 60°C to make Its water content is lower than 3%. After crushing, pass through a 20-mesh sieve, add 6.5 times the amount of water, heat to 100°C and decoct for 2 hours, extract the decoction liquid and filter, and extract the filter residue twice according to the above operation, and then combine 3 The second extract, con...

Embodiment 3

[0032] Embodiment 3: a kind of capsule for the treatment of atrophic gastritis, described capsule is mainly made up of the following components by weight: 12 parts of gentianine, 10 parts of dark russin, 6 parts of betulin, Isorhamna 5 parts of prime, 3 parts of pro-opiate, 0.8 part of pepsin; The capsule also includes auxiliary materials: 85 parts of diluent, 5 parts of disintegrant, 4 parts of lubricant.

[0033] Wherein, the above-mentioned anem rosin is a compound extracted from the root of lingshui anem luosu, and its preparation method is as follows: cutting the root of lingshui anem luosu into thin slices with a thickness of 3 mm, putting it in an oven for drying, and setting the temperature of the oven at 60° C. to make it The water content is less than 3%, crushed and passed through a 20-mesh sieve, add 8 times the amount of water, heat to 100°C and decoct for 2 hours, extract the decoction liquid and filter, then extract the filter residue twice according to the above...

technical field

[0001] The invention relates to the technical field of medication for digestive diseases, in particular to a capsule for treating atrophic gastritis and a preparation method thereof. Background technique

[0002] With the improvement of people's living standards, the incidence of chronic gastritis is getting higher and higher with age, and some patients develop cancer. Chronic atrophic gastritis is a common disease, which refers to the atrophy and metaplasia of the gastric mucosa. Mucosal epithelium and gland atrophy, reduced number, gastric mucosa thinning, mucosal base layer thickening, or with pyloric glandular metaplasia and intestinal glandular metaplasia, often involving the cardia, accompanied by loss of G cells and decreased secretion of gastrin, can also be Involvement of the gastric body, with loss of the oxyntic glands, resulting in a decrease in gastric acid, pepsin, and endogenous factors, or a chronic digestive disorder characterized by dysplasi...

Examples

Embodiment 1

[0018] Embodiment 1: a kind of capsule for the treatment of atrophic gastritis, described capsule is mainly made up of the composition of following parts by weight: 6 parts of gentianine, 5 parts of dark russin, 3 parts of betulin, different mouse 3 parts of lisu, 1 part of pro-opiate, 0.5 part of pepsin; the capsule also includes auxiliary materials: 65 parts of diluent, 3 parts of disintegrant, and 2 parts of lubricant.

[0019] Wherein, the described Anem rosin is a compound extracted from the roots of Anem lingshui, and its preparation method is: cut the roots of Anem lingshui into 2mm thick slices, place them in an oven for drying, and set the temperature of the oven at 60°C to make them The water content is less than 3%, crushed and passed through a 20-mesh sieve, add 5 times the amount of water, heat to 100 ° C for 2 hours, extract the decoction liquid and filter, and then extract the filter residue twice according to the above operation, and then combine three times Co...

Embodiment 2

[0025] Embodiment 2: a kind of capsule for treating atrophic gastritis, described capsule is mainly made up of the following components by weight: 9 parts of gentianine, 7.5 parts of dark russin, 4.5 parts of betulin, and Isorhamna 4 parts of prime, 2 parts of protopine, 0.65 part of pepsin; The capsule also includes auxiliary materials: 75 parts of diluent, 4 parts of disintegrant, 3 parts of lubricant.

[0026]Wherein, the above-mentioned anem rosin is a compound extracted from the root of lingshui anem, and its preparation method is: cut the root of lingshui anem into 2.5mm thick slices, place it in an oven for drying, and set the temperature of the oven at 60°C to make Its water content is lower than 3%. After crushing, pass through a 20-mesh sieve, add 6.5 times the amount of water, heat to 100°C and decoct for 2 hours, extract the decoction liquid and filter, and extract the filter residue twice according to the above operation, and then combine 3 The second extract, con...

Embodiment 3

[0032] Embodiment 3: a kind of capsule for the treatment of atrophic gastritis, described capsule is mainly made up of the following components by weight: 12 parts of gentianine, 10 parts of dark russin, 6 parts of betulin, Isorhamna 5 parts of prime, 3 parts of pro-opiate, 0.8 part of pepsin; The capsule also includes auxiliary materials: 85 parts of diluent, 5 parts of disintegrant, 4 parts of lubricant.

[0033] Wherein, the above-mentioned anem rosin is a compound extracted from the root of lingshui anem luosu, and its preparation method is as follows: cutting the root of lingshui anem luosu into thin slices with a thickness of 3 mm, putting it in an oven for drying, and setting the temperature of the oven at 60° C. to make it The water content is less than 3%, crushed and passed through a 20-mesh sieve, add 8 times the amount of water, heat to 100°C and decoct for 2 hours, extract the decoction liquid and filter, then extract the filter residue twice according to the above...

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