3 results about "Lead blood" patented technology

The invention discloses a method for deriving a lead safety value based on an AAL model of Monte Carlo simulation, and relates to the technical field of data derivation, and the method is technically characterized by comprising the following steps: S1, collecting data and carrying out statistical analysis; s2, adjusting an AAL model: establishing the AAL model through R software, inputting or modifying environmental medium lead concentration, exposure parameters and pharmacokinetic parameters in Excel, setting a lead exposure mode and operating a program, and simulating absorption, distribution, metabolism and excretion of lead by using a differential equation; s3, calculating an external lead intake value through a bisection method; and S4, selecting an uncertain coefficient, and calculating a health guidance value. According to the method, reference can be provided for dietary lead exposure risk assessment, in addition, the AAL model of Monte Carlo simulation can predict the blood lead level of each age according to external environment lead exposure of people, and therefore risk management personnel can utilize the model to carry out biological monitoring and take prevention and control measures according to monitoring data.

This invention relates to a deep learning-based system and method for predicting the risk of re-emergence of blood lead levels after lead poisoning, belonging to the field of intelligent medical technology. The method includes: S1: acquiring raw clinical data of the patient to be evaluated; S2: preprocessing the raw data, including iterative imputation of missing values, nonlinear transformation of skewed continuous variables, and mode imputation and encoding of categorical variables; S3: feature engineering construction, based on the preprocessed data, constructing a low-dimensional engineered feature space with physiological mechanism orientation through cross-dimensional interaction, including the "exposure source-exposure intensity-follow-up trend-organ involvement" chain features and a comprehensive medical index; S4: inputting the constructed features into a pre-trained prediction model, outputting the probability value of re-emergence of blood lead, and performing risk stratification based on the probability value. This invention achieves accurate prediction of re-emergence of blood lead levels in lead poisoning patients after lead chelation therapy.

The invention relates to the technical field of microorganisms, in particular to a metagen for preventing or treating lead poisoning and a preparation method and application thereof.The metagen for preventing or treating lead poisoning is obtained by conducting fermentation culture on paenibacillus bovis BD3526 in a bran culture medium and then inactivating the paenibacillus bovis BD3526, the bacillus subtilis BD3526 comprises inactivated thalli of the bacillus subtilis BD3526 and a metabolite of the bacillus subtilis BD3526. The prepared metagen has the effects of remarkably promoting lead excretion, reducing lead accumulation in the liver or kidney and reducing the content of blood lead.