130 results about "Biomonitoring" patented technology

The invention relates to methods and devices for remote or distributed continuous monitoring of physiologically relevant states. The invention provides for methods to automatically detect deviations or other states in physiological parameters and automatically alert a measured subject, user or other authorized party. The device provides for a universal platform for sensors, and further provides for the automatic compensation or distribution of devices or bioactive agents at appropriate levels and / or intervals in response to deviations or other states sensed in various physiological parameters.

BioMEMS / NEMS appliance biologically monitors an individual, using biosensors to detect cellular components. Data is simulated or analyzed using systems-biology software, which provides diagnostic or therapeutic guidance.

The invention relates to methods and devices for remote or distributed continuous monitoring of physiologically relevant states. The invention provides for methods to automatically detect deviations or other states in physiological parameters and automatically alert a measured subject, user or other authorized party. The device provides for a universal platform for sensors, and further provides for the automatic compensation or distribution of devices or bioactive agents at appropriate levels and / or intervals in response to deviations or other states sensed in various physiological parameters.

A wearable biometric monitoring device is configured to assess the biometric signal quality of one or more sensors associated with the monitoring device, determine how the user should adjust the device to improve the biometric fit, and instruct the user to wear the biometric monitoring device a certain way. Communicating instructions to a user may include instructing the user to execute a testing regimen while wearing the biometric monitoring device. The testing regimen facilitates an estimation of a signal quality that can be used to provide feedback to the user that he / she needs to adjust the device to improve the biometric fit and the biometric signal quality.

A bio-surveillance system monitors symptoms or groups of symptoms experienced by people in a geographical area. The system tracks symptoms reported by calls to an emergency service dispatcher. The bio-surveillance system monitors the symptoms and associates the geographical location with the symptoms. Various triggers are programmed and stored in the system to look for certain types of threats. Each trigger is set based on a statistical variation of the historical data relating to the symptoms within a predetermined time in a predefined geographical area. When the reported symptoms exceed one of the triggers, an alert is activated to provide an indication of a potential biological or chemical terrorist attack.

BioMEMS / NEMS appliance biologically monitors an individual, using biosensors to detect cellular components. Data is simulated or analyzed using systems-biology software, which provides diagnostic or therapeutic guidance.

An automated biomonitoring system for monitoring water quality includes an exposure chamber for housing an aquatic organism having ventilatory behavior and body movement sensitive to water quality. Electrodes capture electrical signals produced by the organism during its ventilatory behavior and body movement, and a controller responsive to signals from the electrodes determines one or more ventilatory parameters based on the signals. The ventilatory parameters are compared with corresponding thresholds to determine when the water to which the organism is exposed has caused physiological stress to the organism. The signals captured by the electrodes may be corrected for variations in water conductivity so that the signals processed by the controlled are not influenced by conductivity.

An automated biomonitoring system for monitoring water quality includes an exposure chamber for housing an aquatic organism having ventilatory behavior and body movement sensitive to water quality. Electrodes sense electrical signals produced by the organism during its ventilatory behavior and body movement, and a controller responsive to signals from the electrodes determines a plurality of ventilatory parameters based on the signals. The ventilatory parameters are compared with corresponding thresholds to determine when the water to which the organism is exposed has caused physiological stress to the organism.

The invention relates to a novel pneumonosis serum marker, namely a Golgi protein gp73, which belongs to the biological monitoring technical field. The invention also discloses an application of the serum Golgi protein gp73 in diagnosing pneumonosis and provides a detection kit for the serum gp73.

The invention relates to a water quality online security early warning system and method thereof. The water quality online security early warning system comprises a biology avoidance behavior sensor which consists of two testing tubes, wherein, the two tubes are communicated through a two-way in the middle and parallel with each other; the two tubes are respectively provided with two groups of stainless steel monitoring electrodes, each group of electrodes consists of a signal transmitting electrode and a signal receiving electrode, wherein, the signal transmitting electrode forms a positive rotation low voltage alternating electric field in the testing tube, and the signal receiving electrode can induce changes of the electric field; the changes of the electric field are transmitted to a signal collecting device, and displayed through a display after being processed. The invention can display behavior change signal of a tested biology with the mode of electrical signal received from multi-point monitoring, can achieve online biology monitoring of original position, online and real time via analyzing and evaluating the electrical signal, and can warn early against unknown contaminants in water body, and has very important indicating effect for the investigations of environmental pollution, in particular for paroxysmal and severe accidental changes.

A portable automated biomonitoring system for monitoring water quality includes an exposure chamber for housing an aquatic organism and a water inlet for directing water to the exposure chamber. The aquatic organism has ventilatory behavior and body movement sensitive to water quality. Electrodes sense electrical signals produced by the organism during its ventilatory behavior and body movement, and a controller responsive to signals from the electrodes determines a plurality of ventilatory parameters based on the signals. The ventilatory parameters are compared with corresponding thresholds to determine when the water to which the organism is exposed has caused physiological stress to the organism. The water being evaluated may be recirculated through the system for further analysis.

Provided is a biomonitoring device that measures a parameter of a material expelled during use of a toilet by a user. Also provided is a biomonitoring mirror device that identifies a user, detects a febrile illness in a user, dispenses medications / supplements, connects to electrical device accessories in the bathroom, and provides an interactive user interface. Additionally provided is a system for measuring a parameter of a material expelled during use of a toilet by a user. Further provided is a method of determining a physiological parameter of a user.

The invention discloses a fish activity method based on a neural network. The method includes the following steps: 1. real-time monitoring crucian as a biological monitoring target; 2. extracting a target fish outline by using background differencing method, real-time monitoring a crucian population, obtaining a tracking video sequence of the crucian; and 3. automatically obtaining texture characteristics of a to-be-monitored fish which is alive or dead through the neural network, comprising the following steps: 3.1. collecting and extracting the outline information data of a fish target, determining whether the quality of the to-be-inspected water is normal or not based on the collected outline information; 3.2. based on the neural network, training the data and generating a mature classifier structure model; 3.3. using new characteristic data to detect and determine whether the detection model is mature; and 3.4. on-line and real-time detecting water quality data by using the mature detection model, and eventually implementing on-line detection of the toxicity of the water quality.

A portable automated biomonitoring system for monitoring water quality includes an exposure chamber for housing an aquatic organism and a water inlet for directing water to the exposure chamber. The aquatic organism has ventilatory behavior and body movement sensitive to water quality. Electrodes sense electrical signals produced by the organism during its ventilatory behavior and body movement, and a controller responsive to signals from the electrodes determines a plurality of ventilatory parameters based on the signals. The ventilatory parameters are compared with corresponding thresholds to determine when the water to which the organism is exposed has caused physiological stress to the organism. The water being evaluated may be recirculated through the system for further analysis.

The invention belongs to the technical field of biological monitoring environment, and specifically relates to a shellfish monitoring method for ocean oil spill pollution. The shellfish monitoring method comprises the steps of utilizing typical bivalve mollusk such as short-necked clam and chlamys farreri in China to determine the shellfish visceral mass autioxidant enzyme activities including superoxide dismutase, glutathione glutathione S-transferase, peroxidase, glutathione peroxidase and catalase activity, integrating the enzyme activities so as to form an integration biomarker responding index (IBR), establishing a dose-effect relationship between the IBNNR and petroleum concentration, adopting a one-dimensional variance components method (ANOVA) to carry out notable difference analysis, determining the forcing degree of petroleum pollution on organisms, and finally judging pollution level of the ocean oil spill.

The invention relates to an affinity sensor for detecting specific molecular binding events, for use in the field of molecular biology, e.g., in medical diagnostics, especially in biosensor technology or in DNA microarreay tests. The aim of the invention is to provide an affinity sensor of this type for rapidity, sensitively, specifically, economically and routinely detecting the presence of molecules, especially bioactive molecules, and to provide special applications for an affinity sensor of this type. To this end, the affinity sensor consists of a support substrate which is provided with at least two electrodes. The electrodes are situated equidistantly from each other and cover an area on both sides, at least this area being provided for receiving immobilized specific binding partners which are capable of coupling complementary corresponding binding partners directly or with other specific binding molecules. The area is established with a minimum width b, in such a way that at least one complementary corresponding binding partner which is provided with an electroconductive particle can be received in the area in such a way as to guarantee the possibility of a tunnel-type contact junction forming between the particle and the electrodes in each case. The affinity sensor is used for biomonitoring.

The invention relates to a river water quality and biological monitoring system and a river water quality and biological monitoring method for an irregularly-shaped region. The system comprises a base station, a communication network and a logic analytical unit, wherein the base station is arranged at a preset position of a river basin, comprises a biological monitoring unit and a water quality monitoring unit, and is used for monitoring the biological and water quality parameters of the position of the base station respectively, acquiring the corresponding index information, sorting signals and transmitting into the logic analytical unit through the communication network, and the logic analytical unit can perform operation to the real-time monitoring data through a constructed monitor model and also can carry out index data evaluation and output the monitoring result. The system and the method comprehensively consider multiple transverse and longitudinal factors of the rivers and territory and topographic factors to construct the parameter monitoring model in real time and obtain the quality evaluation index, therefore, the river can be accurately monitored and evaluated.

The invention provides a water quality mutation-creature behavior index monitoring system and a monitoring method thereof. The water body quality condition is analyzed at real time by monitoring the behavior index change of the creature, and the online creature monitoring of the water body sudden pollution accident is realized. The system provides a plurality of platforms, and provides the control of water body monitoring. Meanwhile, the water flow balanced distribution of different creature sensors of the monitoring technology of the water quality mutation creature behavior indexes is realized by the water flow controller of the system, and the influence on the monitoring result caused by the creature behavior change caused by water flow changes is avoided.

The invention discloses a method for determining biotoxicity of water quanlity based on movement velocity change of zebrafish. The method comprises the following steps: domesticating zebrafish; carrying out acute toxicity test on the domesticated zebrafish and calculating the 48 hour medial lethal concentration; and carrying out behavior test on the domesticated zebrafish, determining the movement velocity change of the zebrafish and judging the biotoxicity of water quality. With movement velocity of the zebrafish in a water environment as a biomarker, the biotoxicity of pollutants is evaluated; the movement behavior of the zebrafish in the water environment is tracked and captured; the movement track of the zebrafish is visually observed at any time; the speed index is determined in real time; quantitative evaluation for determining the biotoxicity of water quality by employing the zebrafish movement velocity change is realized; water quality fluctuation is displayed within a short period of time; the biological monitoring and early warning timeliness, sensitivity and accuracy are improved; a technical support is provided for sudden water body pollution; and the water supply quality safety is ensured.

The invention discloses a method for evaluating biotoxicity of a heavy metal by duckweed thallus separation, which comprises the steps of: creating a correlativity of toxicological reaction of duckweed on the heavy metal, namely, two-leaf separation phenomenon of thallus and the category and concentration of the heavy metal, and evaluating the biotoxicity of a tested water sample by the separation time of the laminae. The method of the invention has the advantages that the duckweed has sensitive toxic response and short response time on certain heavy metals, such as copper and iron, and the like, thereby shortening the test time, saving the cost and simplifying the operation. The duckweed thallus has sensitive physio-ecological response on the heavy metal and the response can be directly observed, so that the duckweed thallus can be used as an effective complementary method for monitoring sewage toxicological effect system of hydrobiont.

Disclosed is a water quality toxicity detection method based on fish activity analysis. The method comprises the following steps that 1, crucian is adopted as a biological monitoring object so as to be subjected to real-time monitoring; 2, a target crucian contour is extracted through conversion from RGB to HSV color space, crucian groups are monitored in real time, and a crucian tracking video sequence is obtained; 3, crucian motion data analysis and detection are performed, wherein 3.1, differences among the crucian velocity speed, a counter area and an area mean value are adopted as main characteristic data; 3.2, a mature detection model is generated on the basis of a Naive Bayes classifier algorithm; 3.3, novel characteristic data is adopted for detecting and judging whether the detection model is mature or not; 3.4, real-time water quality data is detected in an online mode through the mature detection model, and finally online detection of the water quality toxicity is achieved. Online real-time detection can be achieved, sensitivity and continuity of water quality detection can be improved, the detection cost can be lowered, and real-time effective detection can be performed on a large number of unknown water quality toxicity conditions.

The invention discloses a method for determining water quality biotoxicity, which comprises the following steps: domesticating zebra fish; performing acute toxicity test of the domesticated zebra fish and calculating medial lethal concentration of 48 hours; performing behavioristics test of the domesticated zebra fish, determining movement speed change of the zebra fish and judging water quality biotoxicity. The movement speed of the zebra fish in a water environment is used as a biomarker to evaluate the biotoxicity of a pollutant, the movement behavior of the zebra fish in the water environment is traced and captured, the movement trail of the zebra fish is intuitively observed anytime, a speed index is determined in real time, the quantified evaluation of the water quality biotoxicity is determined by using the movement speed change of the zebra fish, a water quality fluctuation condition is reflected in short time, timeliness, sensitivity and accuracy of biological monitoring early warning are improved, an early warning technical support is provided for acute water body pollution, and safety of water quality of supplied water is guaranteed.

The invention provides quick analysis equipment for monitoring operating states of sewage treatment plants. The quick analysis equipment comprises a sampling unit, a monitoring unit, a data processing unit and a power unit. The sampling unit comprises a sample pipeline and a sampling pump; the monitoring unit comprises a monitoring barrel, a sludge monitoring device and a biological monitoring device, the monitoring barrel is used for accommodating to-be-monitored fluid, and samples in the monitoring barrel can be monitored by the sludge monitoring device and the biological monitoring device; the data processing unit is provided with stored databases, data in the databases include diversified sludge settling behavior parameters and diversified microorganism data under different natural conditions and process operating conditions, data from the sludge monitoring device and the biological monitoring device can be acquired by the data processing unit, the acquired data and the data in the stored databases are compared and processed by the data processing unit, and state reports related to the operating states of the sewage treatment plants can be generated by the data processing unit. The invention further provides a method for monitoring the operating states of the sewage treatment plants by the aid of the quick analysis equipment.

The invention relates to an abnormal water detection method based on immune negative selection, which comprises the following steps: 1) carrying out real-time monitoring with zebra fish as an object of biological monitoring; 2) carrying out real-time detection and tracking of the zebra fish through a multi-target tracking algorithm based on particle filtering, thereby obtaining a zebra fish tracking video sequence; and 3) analyzing and detecting water data, which comprises the following steps: 3.1) producing a large amount of novel data through high-frequency variation of a self-set and simultaneously carrying out low-frequency variation of the self-set; 3.2) producing a maturity detector through a detector generating algorithm based on negative selection; 3.3) judging whether the detector set is mature through combination of expectation coverage and overlapping coefficient calculation (W); and 3.4) carrying out online detection of real-time water data with the maturity detector and finally carrying out online detection of the abnormal water. The invention does not need a large amount of abnormal data, thereby reducing the detection cost and improving the real-time detection.

The invention relates to a shellfish monitoring method of freshwater environment heavy metal pollution and trace elements accumulation, which belongs to the biological monitoring environment technology field. The invention is characterized in that anodonta woodiana living heudes are selected to be raised in aerated water. Impurities in a shell and a digestive tract are eliminated. Then, the heudes are dissected and soft tissues of the heudes are obtained and preserved in a refrigerator. A heude soft tissue dry sample is fetched and put in a vessel washed with acid. Acid hydrolysis happens at room temperature. A microwave oven is used for low fire resolution. Water is used to determine volume and solution to be detected is prepared. The invention has the advantages of convenient sampling and simple pretreatment method. With an inductively coupled plasma mass spectrometer, trace elements pollutants in shellfish anodonta woodiana living heudes can be precisely determined and indicated. Concentrations, components characteristics, pollution degree, biological toxicity effects and differences between waters of various pollutants can be rapidly known. The invention has the advantages of good stability, high reproducibility, high comparability and small system error. Harm risks on fishery waters and development trends of all pollutants can be precisely assessed and predicated.

A system for managing discharge of patients from a hospital to a nursing care facility has the steps of a nursing facility registers on the database, the nursing facility providing real-time updates on a current bed availability, the database is updated with the bed availability as well as features of the available bed, an up-to-date view of bed availability is provided to a hospital case managers view bed availability, and the patient is discharged and sent to the available bed. The features are selected from the group consisting of gender, isolation beds, subacute conditions, custodial beds and the presence of a ventilator. The system may also have the step of placing a biomonitoring device on a patient and monitoring the patient. Monitoring the patient may include locating the patient within the facility, monitoring vital functions, and monitoring for early stroke detection.

The invention discloses a method for preparing a water-soluble copolymer by using pyrenemethyl acrylate, and belongs to the technical field of functional polymers. The fluorescent copolymer is prepared by the following steps of: performing esterification reaction on pyrenemethanol and acryloyl chloride to obtain the pyrenemethyl acrylate; and performing copolymerization reaction on the pyrenemethyl acrylate and dimethylaminoethyl methacrylate to obtain the water-soluble fluorescent copolymer, and performing a series of characterizations on the copolymer. The invention has the advantages that: the synthetic process for the water-soluble fluorescent copolymer is simple and feasible; a side chain of the synthesized polymer is provided with a pyrene fluorescence group with relatively high yield of fluorescent quanta and a hydrophilic amino group; and the polymer has temperature and pH responsiveness, and the like, is easy to operate in the aspect of the application of biological monitoring, and has a great scientific significance and important application value for disclosing diseases and gene mutation and the like.

A system and method for mechanical CPR can include a device for providing compressive force to various locations on a patient, and biological monitoring systems to measure the effectiveness of the various locations of compressive force in pumping blood through the patient. The system can also include providing decompressive force to increase the efficacy of blood flow.

A soft, flexible microtube sensor and associated method of sensing force are described. A liquid metallic alloy is sealed within a microtube as thin as a strand of human hair to form the physical force sensing mechanism. The sensor is hardly distinguishable with the naked eye, and can be used for the continuous biomonitoring of physiological signals, such as unobtrusive pulse monitoring. Also described is a method of fabricating the microtube sensor and wearable devices incorporating one or more microtube sensors.