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2 results about "DNA microarray" patented technology
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A DNA microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface. Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome. Each DNA spot contains picomoles (10⁻¹² moles) of a specific DNA sequence, known as probes (or reporters or oligos). These can be a short section of a gene or other DNA element that are used to hybridize a cDNA or cRNA (also called anti-sense RNA) sample (called target) under high-stringency conditions. Probe-target hybridization is usually detected and quantified by detection of fluorophore-, silver-, or chemiluminescence-labeled targets to determine relative abundance of nucleic acid sequences in the target. The original nucleic acid arrays were macro arrays approximately 9 cm × 12 cm and the first computerized image based analysis was published in 1981. It was invented by Patrick O. Brown.
Image acquisition device, image acquisition method, and image acquisition program
PendingJP2026104878ABioreactor/fermenter combinationsBiological substance pretreatmentsDNA microarrayRadiology
To obtain fluorescence images with high detection accuracy. [Solution] The image acquisition device 100 acquires a first fluorescence image of DNA microarray A captured by imaging device 1 during a first period and a second fluorescence image of DNA microarray A captured by imaging device 1 during a second period. Based on the first fluorescence intensity of the fluorescence spots that emit fluorescence in the first fluorescence image, it corrects the second fluorescence intensity of the fluorescence spots that emit fluorescence in the second fluorescence image to generate a corrected second fluorescence image. The corrected second fluorescence image is added to the first fluorescence image to generate an additively corrected fluorescence image of the corrected first fluorescence image.
Owner:YOKOGAWA ELECTRIC CORP
DNA microarrays and component level sequencing for nucleic acid-based data storage and processing
PendingUS20260038590A1Microbiological testing/measurementDigital storageDNA microarrayTesting Methods
Technologies include systems, devices, and methods to write, store, read, and perform computation of digital information using nucleic acid molecules (e.g., DNA). The technologies include, for example, a device including one or more individually or block-addressable electrode micro-arrays or nano-arrays to write, store, retrieve, read, and compute / manipulate digital information.
Owner:BIOMEMORY AMERICA LLC