The present disclosure relates to methods and compositions for the production of phytonutrients in
microbiome. Methods are disclosed that can be used to provide phytonutrients to a subject via mediating the
microbiome of the subject. The methods include administering to a subject a
plant functional composition to alter the state of a phytonutrient producer in the subject. The method may also include identifying a phytonutrient producer status of the subject by evaluating a level of at least one of a preselected phytonutrient and a preselected phytonutrient precursor compound in the subject. Also disclosed are
plant functional compositions useful in the methods and comprising a phytonutrient precursor compound and an
active agent. The
active agent comprises probiotics and / or prebiotics and is adapted to mediate the production of the preselected phytonutrients in the
gastrointestinal tract of the subject, thereby altering the phytonutrient producer status of the subject.