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51 results about "Subtilase" patented technology
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Subtilases are a family of subtilisin-like serine proteases. They appear to have independently and convergently evolved an Asp/Ser/His catalytic triad, like in the trypsin serine proteases. The structure of proteins in this family shows that they have an alpha/beta fold containing a 7-stranded parallel beta sheet.
Protease variants and compositions
The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved autoproteolytic stability in comparison to their wild type parent enzymes.
Owner:NOVOZYMES AS
Subtilase variants
The present invention relates to subtilase variants having a reduced tendency towards inhibition by substances present in eggs, such as trypsin inhibitor type IV-0. In particular, the variants comprise at least one additional amino acid residue between positions 42-43, 51-56, 155-161, 187-190, 216-217, 217-218 or 218-219 (in BASBPN numbering). These subtilase variants are useful exhibiting excellent or improved wash performance on egg stains when used in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dishwash composition, including automatic dishwash compositions. Also, isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention. Further, cleaning and detergent compositions comprising the variants are disclosed.
Owner:NOVOZYMES AS
Subtilase enzymes
The present invention relates to subtilases having a reduced tendency towards inhibition by substances present in eggs, such as the trypsin inhibitor type IV-0. These subtilases are useful exhibiting excellent or improved wash performance on egg stains when used in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dishwash compositions, including automatic dishwash compositions.
Owner:NOVOZYMES AS
Subtilases
InactiveUS20070015240A1Improve thermal stabilityHigh activityBacteriaSugar derivativesGeneticsBiochemistry
The present invention relates to methods for producing variants of a parent JP170 subtilase and of a parent BPN′ subtilase and to JP170 and BPN′ variants having altered properties as compared to the parent JP170 / BPN′ subtilase.
Owner:NOVOZYMES AS
Subtilase variants
The present invention relates to subtilase variants having a reduced tendency towards inhibition by substances present in eggs, such as trypsin inhibitor type IV-0. In particular, the variants comprise at least one additional amino acid residue between positions 42–43, 51–56, 155–161, 187–190, 216–217, 217–218 or 218–219 (in BASBPN numbering). These subtilase variants are useful exhibiting excellent or improved wash performance on egg stains when used in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dishwash composition, including automatic dishwash compositions. Also, isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention. Further, cleaning and detergent compositions comprising the variants are disclosed.
Owner:NOVOZYMES AS
Variant subtilisin enzymes (subtilases)
Novel subtilases having an improved wash performance on egg stains are disclosed. These subtilases are useful exhibiting excellent or improved wash performance on egg stains when used in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
Owner:NOVOZYMES AS +1
Novel subtilases
The present invention relates to methods of producing parental TY145 subtilase variants and parental BPN' subtilase variants, and to TY145 and BPN' variants having altered properties compared to the parental TY145 / BPN' subtilase variants.
Owner:NOVOZYMES AS
Cytotoxin with a subtilase domain
A member of a new class of bacterial toxin has been isolated and characterised. The bacterial toxin is of the AB5 type and is characterised in that it has a subtilase domain. It is cytotoxic to Vero cells, and toxicity in vivo in mice occurs in a number of different sites. Mutation of the serine active residue results in greater than 99% reduction in activity. The protein has been purified and antibodies have been prepared for both the A subunit and B subunits, and ELISA detection methods have been developed. The nucleic acid sequence has been determined and primers specific for the toxin have been used for a preliminary screen of a range of patient samples to ascertain the extent to which the toxin is present.
Owner:INOVIQ LTD
Subtilases and subtilase variants having altered immunogenicity
InactiveUS20060228791A1Enable heterologous recombinant productionCosmetic preparationsFungiBiologyVaccine Immunogenicity
The present invention relates to subtilase variants and subtilases with an altered immunogenicity, particularly subtilase variants and subtilases with a reduced allergenecity. Furthermore, the invention relates to expression of said subtilase variants and subtilases and to their use, such as in detergents and oral care products.
Owner:NOVOZYMES AS
Subtilases and subtilase variants having altered immunogenicity
The present invention relates to subtilase variants and subtilases with an altered immunogenicity, particularly subtilase variants and subtilases with a reduced allergenecity. Furthermore, the invention relates to expression of said subtilase variants and subtilases and to their use, such as in detergents and oral care products.Owner:NOVOZYMES AS
Subtilases
InactiveUS20090203111A1Improve thermal stabilityHigh activityBacteriaSugar derivativesSubtilaseImmunology
The present invention relates to methods for producing variants of a parent JP170 subtilase and of a parent BPN′ subtilase and to JP170 and BPN′ variants having altered properties as compared to the parent JP170 / BPN′ subtilase.
Owner:NOVOZYMES AS
Subtilase variants
The present invention relates to protease variants.The present invention also relates to polynucleotides encoding the variant protease variants and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides, and methods of using the variant enzymes, such as, in laundry and detergent compositions.
Owner:NOVOZYMES AS
Savinase variants having an improved wash performance on egg stains
Subtilase variants having an improved wash performance on egg stains. These subtilases are useful exhibiting excellent or improved wash performance on egg stains when used in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
Owner:NOVOZYMES AS
Detergent composition comprising subtilase variants
InactiveUS20180148670A1Detergent mixture composition preparationDetergent compounding agentsSurface cleaningLaundry
The present disclosure relates to a detergent composition, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions comprising subtilase variants. The present disclosure also relates to the use of said detergent compositions in a cleaning process such as laundry or hard surface cleaning. The present disclosure further relates to a method for removing a stain from a surface, which comprises contacting the surface with the detergent composition.
Owner:HENKEL KGAA
Subtilase Variants
InactiveUS20090163400A1Good storage stabilityImprove performanceBacteriaHydrolasesWild typeBacillus subtilis
The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved stability and/or improved wash performance in any detergent in comparison to their wild type parent enzymes. The enzymes are well-suited for use in any detergent and for some in especially liquid or solid shaped detergent compositions.
Owner:NOVOZYMES AS
Method for preparing vegetable cultivation medium by virtue of earthworm hydrolysate
InactiveCN105084953AImprove survival rateImprove water and fertilizer retention performanceSubtilisinFeces
The invention relates to a method for preparing a vegetable cultivation medium by virtue of earthworm hydrolysate, and belongs to the field of nutrition media for plants and making methods for the nutrition media. The vegetable cultivation medium is prepared by breeding earthworms with stacked poultry and livestock manure to convert the manure for feeding the earthworms into earthworm cast, mixing the bred earthworms and subtilisin to automatically hydrolyze the earthworms to obtain the earthworm hydrolysate and adding a proper amount of peat into a mixture of the earthworm cast and the earthworm hydrolysate. Examples show that the method is unique and novel; the prepared cultivation medium is high in water and fertilizer retention, and plant roots can be easily fixed; moreover, the cultivation medium contains large amounts of amino acids and proteins, so that survival rates of cultivated vegetables are remarkably increased by over 88 percent.Owner:CHANGZHOU SIYU ENVIRONMENTAL PROTECTION MATERIAL SCI & TECH
Subtilase variants having altered lmmunogenicity
The present invention relates to subtilase subtilases with an altered immunogenicity, particularly subtilases with a reduced allergenicity. Furthermore, the invention relates to expression of said subtilase variants and subtilases and to their use, such as in detergents and oral care products.
Owner:NOVOZYMES AS
Variant proteases and amylases having enhanced storage stability
ActiveUS10550381B2Improve stabilityImprove surface propertiesDetergent compounding agentsDetergent materialsBiotechnologyAmylase
The present invention relates to novel subtilase variants exhibiting increased stability and preferably on par or improved wash performance. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention.
Owner:NOVOZYMES AS
Subtilase Variants and Polynucleotides Encoding Same
InactiveUS20140335596A1Convenient ligationImprove surface propertiesDetergent compounding agentsPeptidasesProteinase activityNucleotide
The present invention relates to protease variants and methods for obtaining protease variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Owner:NOVOZYMES AS
Detergent composition comprising subtilase variants
ActiveUS10760036B2Improve stabilityDetergent compounding agentsPeptidasesBiochemistryOrganic chemistry
The present disclosure relates to detergent compositions comprising subtilase variants exhibiting improved stability and / or improved wash performance in liquid detergent and methods for obtaining such detergent compositions. The variants are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
Owner:HENKEL KGAA
Subtilase variants
ActiveUS10995304B2Improve stabilityImprove washing effectDetergent compounding agentsPeptidasesMicrobiologyProtease
The present invention relates to novel protease variants exhibiting improved stability and or improved wash performance in liquid detergent. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention.
Owner:NOVOZYMES AS
Subtilase variants and compositions comprising same
PendingUS20210189297A1Improve stabilityGood storage stabilityDetergent compounding agentsPeptidasesPolynucleotideSubtilase
The invention relates to subtilase variants having improved stability, compositions comprising the variants, in particular detergent compositions, polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; as well as methods of producing the variants and methods for stabilizing a subtilase variant
Owner:NOVOZYMES AS
Subtilase Variants
InactiveUS20120165241A1Good storage stabilityImprove performanceBacteriaHydrolasesWild typeBacillus subtilis
The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved stability and / or improved wash performance in any detergent in comparison to their wild type parent enzymes. The enzymes are well-suited for use in any detergent and for some in especially liquid or solid shaped detergent compositions.
Owner:UNILEVER PLC +1
Subtilase Variants and Polynucleotides Encoding Same
InactiveUS20140342433A1Increase protease activitySpeed up the conversion processDetergent compounding agentsPeptidasesPolynucleotideCell biology
The present invention relates to subtilase variants and methods for obtaining subtilase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
Owner:NOVOZYMES AS
Detergent composition comprising subtilase variants
ActiveUS20170349861A1Satisfactory wash performanceImprove stabilityDetergent compounding agentsPeptidasesOrganic chemistryLaundry detergent
The present disclosure relates to detergent compositions comprising subtilase variants exhibiting improved stability and/or improved wash performance in liquid detergent and methods for obtaining such detergent compositions. The variants are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
Owner:HENKEL KGAA
Subtilase variants and polynucleotides encoding same
The present invention relates to subtilase variants suitable for use in, e.g., cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention.
Owner:NOVOZYMES AS
Subtilase variants with enhanced storage stability
ActiveUS11015183B2Improve stabilityImprove surface propertiesDetergent materialsDetergent compounding agentsBiotechnologyVariome
The present invention relates to novel subtilase variants exhibiting increased stability and preferably on par or improved wash performance. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention.
Owner:NOVOZYMES AS
Cytotoxin with a subtilase domain
A member of a new class of bacterial toxin has been isolated and characterised. The bacterial toxin is of the AB5 type and is characterised in that it has a subtilase domain. It is cytotoxic to Vero cells, and toxicity in vivo in mice occurs in a number of different sites. Mutation of the serine active residue results in greater than 99% reduction in activity. The protein has been purified and antibodies have been prepared for both the A subunit and B subunits, and ELISA detection methods have been developed. The nucleic acid sequence has been determined and primers specific for the toxin have been used for a preliminary screen of a range of patient samples to ascertain the extent to which the toxin is present.
Owner:INOVIQ LTD
Subtilase variants and polynucleotides encoding same
The present invention relates to subtilase variants suitable for use in, e.g., cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions. The present invention also relates to isolated DNA sequences encoding the variants, expression vectors, host cells, and methods for producing and using the variants of the invention.
Owner:NOVOZYMES AS
Liquid laundry detergent composition
ActiveUS20190382690A1Improve stabilityDetergent mixture composition preparationDetergent compounding agentsLiquid laundry detergentOrganic chemistry
The present invention relates to a liquid detergent composition comprising a novel protease, more in particular a novel and subtilase variant with increased stability, a method for (dish) washing using said liquid detergent composition and a use of said liquid composition in a (dish) washing process.
Owner:CONOPCO INC D B A UNILEVER
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