The invention discloses special selenium-rich and molybdenum-rich fertilizer for bitter gourds. The fertilizer is prepared from raw materials as follows: boron fulvate, ammonium carbonate, calcium superphosphate, potassium chloride, a microbial growth regulator, iron fulvate, composted cow dung, fly ash, carbendazol, a urease inhibitor, octyl mercaptan, sodium borate, bagasse powder, organophosphorus bacterial fertilizer, borax, thiram wettable powder, organic microelements, biomass ash, molybdate and inorganic selenium salt. The organic microelements comprise a tartaric acid complex, a sucrose complex and a humic acid complex. The special selenium-rich and molybdenum-rich fertilizer for bitter gourds has the advantages that the bitter gourd yield is high, the disease resistance of plantsis high and the fertilizer is suitable for large-area application. Besides, fruited bitter gourds are larger, heavy and good in quality, and selenium-rich and molybdenum-rich bitter gourds contain selenium and molybdenum essential to the human body and animals, have high nutrient value and are beneficial to health.