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Mouse space memory retention model and intelligent action inspecting system

A technology of memory retention and behavior, applied in teaching models, medical science, special data processing applications, etc., can solve the problems of sending the isolated area back to the data collection area, and the single space structure of the channel, so as to avoid inconsistent residence time and have a mild effect Effect

Inactive Publication Date: 2009-03-25
SHENYANG MEDICAL COLLEGE
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Problems solved by technology

[0010] Because the spatial memory retention model of the mouse of the present invention adopts a circular black box-type maze as a behavioral data collection device, with a closed circuit of a specified clockwise or counterclockwise path, using controllable lighting to adapt to the dark habit of the mouse, so that it can be used in the box. The autonomous movement in the body, combined with the different gradient voltage bands generated by the electric shock conductors installed at the bottom of the fences in each area, is driven by electric shock stimulation to randomly control the passive movement of the rats, so the training simulation environment of the experimental rats is more in line with the normal physiological and behavioral activities of animals. In fact, it is applicable to both fasting and non-fasting rats, and it will also greatly overcome the shortcomings of the existing long strip multi-channel maze that the rats must be sent from the isolation area to the data collection area through the conveyor belt, and the channel space structure is single.

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  • Mouse space memory retention model and intelligent action inspecting system
  • Mouse space memory retention model and intelligent action inspecting system
  • Mouse space memory retention model and intelligent action inspecting system

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Embodiment Construction

[0020]according to Figure 1-4 The specific structure of the present invention will be described in detail. A model of spatial memory retention in experimental rats employs a maze with a data acquisition area, a target area and its connecting passages. The maze adopts a circular camera obscura maze with multi-channel closed loops (such as Figure 1-2 As shown), in the box body 1 with the upper cover 12 and the fence bottom 6, according to the experimental requirements, a plug-in partition partition is arranged radially through the inner wall of the box body 1 and the chute 8, 11 of the middle column 4 9. Divide the inner chamber of the box 1 into at least three test areas, one of which is the target area, and the rest are data collection areas. In this embodiment, five test areas are adopted, that is, one target area and four data collection areas. Among the five test areas set up, area I, area II, and area III are signal collection areas for the passage of experimental mic...

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Abstract

A mouse's space memory holding model and its intelligent behavior detection system are disclosed. A circular dark box type labyrinth is used as the behavior data acquiring unit. The mouse to be tested passes through a tubular channel with adjustable one-way gates along a pointed path and closed loop for performing the cyclic training. The signals about the active movement and passive movement caused by electric shock are acquired and processed by the data processing control unit. Said signals are transmitted via PCI bus to the Access database in control system, and then processed by the statistical software package, so controlling and monitoring the behavior of mouse at any time.

Description

technical field [0001] The invention relates to a model and a detection system related to research and establishment of animal learning and memory behavior training methods, in particular to an intelligent behavior detection system for a mouse space memory retention model. It can be applied in the fields of neurophysiology, neuropharmacology, neurophysiology and psychology. Background technique [0002] At present, animal behavior experiments are indispensable and important means for studying advanced brain functions and other neurosciences, especially in behavioral medical research such as neurophysiology and neuropharmacology. Among them, the maze test is a classic project of behavioral experiments, and it is one of the most commonly used experiments to study the learning and memory function of rats (or mice), and it is also a commonly used animal model for cognitive drug screening. There are many types of labyrinth devices, but they all include three basic components: tr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61D99/00A01K15/02G06F19/00G09B23/36
Inventor 朱启文牟军曹伟平
Owner SHENYANG MEDICAL COLLEGE
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