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Chinese medicine for treating and preventing early diabetes and nephropathy

A technology for diabetic nephropathy and traditional Chinese medicine, applied in the fields of urinary system diseases, metabolic diseases, drug combinations, etc., can solve problems such as poor targeting, affecting curative effect, and incompleteness.

Active Publication Date: 2009-09-09
天津同仁堂集团股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Diabetic nephropathy is a disease of "deficiency in origin and excess in superficiality". The etiology and pathogenesis are intricate. Although the pure Chinese medicines disclosed above have certain curative effects, after all, the compatibility of drugs for the etiology and pathogenesis of the disease is not comprehensive, and the pertinence is not strong. long-term stable curative effect; and for diabetic nephropathy, it is of great significance to prevent the occurrence of the disease, so the existing technology has limitations in the prevention and clinical application of this disease

Method used

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  • Chinese medicine for treating and preventing early diabetes and nephropathy
  • Chinese medicine for treating and preventing early diabetes and nephropathy
  • Chinese medicine for treating and preventing early diabetes and nephropathy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0147] Example 1 Preparation of Tablets

[0148] Take the raw materials according to the following weight ratio:

[0149] Rehmannia glutinosa 100g Chinese yam 100g Alisma 50g Smilax tuckahoe 100g Bellflower 100g

[0150] Imperata 150g Eucommia 60g Motherwort 100g American Ginseng 30g Ginseng 10g

[0151] Salvia 50g Black beans 100g Hedyotis diffusa 50g

[0152] Preparation:

[0153] Take Chinese yam, Smilax smilax, and Campanulaceae in the prescription and grind them into fine powder, and grind the salvia miltiorrhiza, ginseng, and American ginseng in the prescription into fine powder respectively; Extract twice with water, the first 1.5 hours, add 8 times the amount of water, the second time 1 hour, add 7 times the amount of water, each time the extraction water temperature is 98-102°C, filter the extract, combine the filtrates, and concentrate under reduced pressure to relative density 1.35-1.40 (60±5℃ thermal measurement) extract; add yam, Smilax tuckahoe, platycodon ro...

Embodiment 2

[0154] Example 2 Preparation of Capsules

[0155] Take the raw materials according to the following weight ratio:

[0156] Rehmannia glutinosa 120g Chinese yam 160g Alisma 60g Smilax tuckahoe 150g Bellflower 150g

[0157] Imperata root 200g Eucommia 100g Motherwort 160g American ginseng 40g Panax ginseng 20g

[0158] Salvia 120g Black beans 160g Hedyotis diffusa 80g

[0159] Preparation:

[0160] Take Chinese yam, Smilax smilax, and Campanulaceae in the prescription and grind them into fine powder, and grind the salvia miltiorrhiza, ginseng, and American ginseng in the prescription into fine powder respectively; Extract twice with water, the first 1.5 hours, add 8 times the amount of water, the second time 1 hour, add 7 times the amount of water, each time the extraction water temperature is 98-102°C, filter the extract, combine the filtrates, and concentrate under reduced pressure to relative density 1.35-1.40 (60±5℃ thermal measurement) extract; add yam, Smilax tuckahoe,...

Embodiment 3

[0161] Example 3 Preparation of Tablets

[0162] Take the raw materials according to the following weight ratio:

[0163] Rehmannia glutinosa 80g Chinese yam 80g Alisma 40g Smilax smilax 50g Bellflower 50g

[0164] Imperata 100g Eucommia 50g Motherwort 80g American Ginseng 20g Ginseng 6g

[0165] Salvia 40g Black beans 80g Hedyotis diffusa 40g

[0166] Preparation:

[0167] Take the Chinese yam in the prescription and grind it into fine powder, and grind the salvia miltiorrhiza, ginseng, and American ginseng in the prescription into fine powder respectively; The first time, 1.5 hours, add 8 times the amount of water, the second time 1 hour, add 7 times the amount of water, each time the extraction water temperature is 98-102 ° C, filter the extract, combine the filtrates, and concentrate under reduced pressure to a relative density of 1.35-1.40 (60 ± 5 ℃ heat measurement) extract; Smilax tuckahoe was extracted twice with ethanol, each extraction was 1.5 hours, the extracti...

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Abstract

The invention relates to a traditional Chinese medicine for preventing and treating early diabetic nephropathy. The purpose of the invention is to overcome the deficiencies of the prior art. According to the principle of syndrome differentiation and treatment in the motherland, a Chinese medicine with the functions of nourishing qi and nourishing yin, nourishing kidney and spleen, promoting blood circulation and removing blood stasis, diuresis and eliminating water is disclosed. Swelling, detoxification effect of internal medicine; the present invention is a total of thirteen flavors of American ginseng, ginseng, salvia miltiorrhiza, rehmannia glutinosa, Chinese yam, Alisma, smilax, platycodon grandiflorum, rhizoma rhizome, Eucommia ulmoides, motherwort, black beans and hedyotis diffusa Composition of raw materials, and according to the different characteristics of each traditional Chinese medicine, they are respectively crushed into fine powder, extracted with water and other pretreatments, and then mixed in proportion to make dosage forms such as tablets, capsules, granules, etc.; The data prove that it is suitable for the prevention and treatment of early diabetic nephropathy. It has an excellent effect on symptoms such as fatigue, backache and legs, swelling of the face, dizziness and proteinuria, and has no toxic side effects. It is worthy of promotion and use.

Description

technical field [0001] The present invention relates to a kind of traditional Chinese medicine for preventing and treating diabetic nephropathy, in particular to a kind of medicine which is made from Chinese herbal medicine and has the functions of nourishing qi and nourishing yin, tonifying kidney and strengthening spleen, promoting blood circulation and removing blood stasis, diuresis and detumescence, and clearing away residual toxins. , and a traditional Chinese medicine preparation that has excellent curative effects on fatigue, weak waist, weak legs, swollen face, dizziness and proteinuria. Background technique [0002] Diabetic nephropathy, also known as diabetic glomerulosclerosis, is a severe microvascular complication unique to diabetes and the leading cause of death in diabetic patients. [0003] Traditional Chinese medicine believes that diabetic nephropathy develops on the basis of deficiency of both qi and yin in diabetes. Chronic illness leads to blood stasis,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K36/896A61K36/8945A61K36/884A61K36/804A61K36/74A61K36/533A61K36/53A61K36/46A61K36/34A61K36/258A61K9/48A61K9/20A61K9/16A61P13/12A61P3/10
Inventor 邵世宏
Owner 天津同仁堂集团股份有限公司
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