Gynaecologic antibiotic gel and preparation method and application thereof
A technology of weight and composition, applied in the direction of pharmaceutical formulations, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem of antibacterial cleaning applications that are rarely reported in reports, limited to wound repair in the field of cosmetics, etc. question
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Embodiment 1
[0013] The pharmaceutical composition containing 10.0% by weight of aloe mesophyll colloid, 0.1% by weight of silver sulfadiazine, 1.0% by weight of borneol, and 0.1% by weight of carboxymethylcellulose was prepared.
[0014] Weigh 10 g of commercially available borneol, dissolve in 200 mL of 99% ethanol, and set aside.
[0015] Weigh 1 g of commercially available carboxymethyl cellulose, add it to 700 mL of sterile distilled water, swell at room temperature for 4 hours, and then stir for 4 hours to fully dissolve. Add 100 mL of commercially available 1:1 aloe mesophyll colloid, 1 g of commercially available silver sulfadiazine dry powder, and the above-mentioned borneol solution to the solution. After homogenization, adjust the pH to 4.5 with triethanolamine to obtain a milky white gel.
Embodiment 2
[0017] The pharmaceutical composition containing 20.0% by weight of aloe mesophyll colloid, 1.0% by weight of silver sulfadiazine, 5.0% by weight of borneol, and 1.0% by weight of carboxymethylcellulose was prepared.
[0018] Weigh 50 g of commercially available borneol, dissolve in 200 mL of 99% ethanol, and set aside.
[0019] Weigh 10 g of commercially available carboxymethyl cellulose, add it to 580 mL of sterile distilled water, swell at room temperature for 4 hours, and then stir for 4 hours to fully dissolve. Add 200 mL of commercially available 1:1 aloe mesophyll colloid, 10 g of commercially available silver sulfadiazine dry powder, and the above-mentioned borneol solution to the solution. After homogenization, adjust the pH value to 5.0 with triethanolamine to obtain a milky white gel.
Embodiment 3
[0021] The pharmaceutical composition containing 30.0% by weight of aloe mesophyll colloid, 0.6% by weight of silver sulfadiazine, 3.0% by weight of borneol, and 2.0% by weight of carboxymethylcellulose was prepared.
[0022] Weigh 30 g of commercially available borneol, dissolve in 200 mL of 99% ethanol, and set aside.
[0023] Weigh 20 g of commercially available carboxymethyl cellulose, add it to 480 mL of sterile distilled water, swell at room temperature for 4 hours, and then stir for 4 hours to fully dissolve. Add 300 mL of commercially available 1:1 aloe mesophyll colloid, 1 g of commercially available silver sulfadiazine dry powder, and the above-mentioned borneol solution to the solution. After homogenization, adjust the pH value to 5.0 with triethanolamine to obtain a milky white gel.
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