Hepatitis B virus e antigen testing corpuscle, preparation and application thereof

A hepatitis B and antigen technology, applied in the field of hepatitis B virus e antigen detection particles
CN101251540AActive Publication Date: 2008-08-27BEYOND DIAGNOSTICS (SHANGHAI) CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
BEYOND DIAGNOSTICS (SHANGHAI) CO LTD
Publication Date
2008-08-27

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Abstract

The invention relates to a diagnosing reagent for hepatitis B, disclosing detection grains for e antigens of the hepatitis B virus, which are of the luminous grains coated by anti-HBE antibodies. The invention also discloses preparation and application for the detection grains for e antigens of the hepatitis B virus; moreover, the invention further discloses an outside-body diagnosis reagent box for detecting e antigens of the hepatitis B in a blood serum sample of human beings as well as a method for utilizing the light excitation chemiluminescence principle to quantitatively and qualitatively detect e antigens of the hepatitis B virus. The reagent box of the invention can be jointly used to diagnose the individual acute or chronic hepatitis B together with other blood serums and clinic information, and screen the hepatitis B for women in the perinatal period so as to judge the risk of newborn babies contaminating the hepatitis B.
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Description

technical field

[0001] The invention relates to a diagnostic reagent for hepatitis B, in particular to a particle for detecting hepatitis B virus e antigen based on the principle of light-induced chemiluminescence, its preparation and application. Background technique

[0002] Immunological detection is a means of detection based on the specific reaction of antigens and antibodies. Because it can use isotopes, enzymes, chemiluminescent substances, etc. to amplify and display the detected signals, it is often used to detect proteins, hormones, etc. trace bioactive substances.

[0003] Immunological testing in my country has basically experienced radioimmunoassay (emerged in the 1970s, and is still widely used in hospitals above the county level); enzyme-linked immunoassay (emerged in the 1980s, commonly used in various clinical institutions); Photobiological labeling and immunoassay technology represented by luminescence (began to be popularized and used in the 1990s, and the...

Claims

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