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Compound injection medicine composite for treating pig, cattle respiratory disease

A composition and respiratory technology, which is applied in the field of compound injection pharmaceutical composition, can solve the problems of food safety, drug resistance, large dosage, and reduced therapeutic effect at the time of use.

Inactive Publication Date: 2009-05-06
QINGDAO VLAND BIOTECH INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] The existing combination of antibiotics and flunixin meglumine on the market includes oxytetracycline or the compound preparation of florfenicol and flunixin meglumine, but due to the large dosage and the increase of the use time of these drugs, Food safety issues and drug resistance have arisen, and the therapeutic effect has also been severely reduced, and the combination of Tulathromyin and flunixin meglumine has not been reported

Method used

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  • Compound injection medicine composite for treating pig, cattle respiratory disease
  • Compound injection medicine composite for treating pig, cattle respiratory disease
  • Compound injection medicine composite for treating pig, cattle respiratory disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] Components of telamectin-flunixin meglumine compound injection pharmaceutical composition:

[0091] 100ml contains:

[0092] Tulathromycin: 5.0g

[0093] Flunixin meglumine: 4.15g

[0094] Citric acid: 0.15g

[0095] Thioglycerol: 0.5g

[0096] Thioglycolic acid: 0.1g

[0097] Sodium edetate: 0.5g

[0098] Water for injection to : 100ml

[0099]HCL or NaOH solution to adjust the pH to 4.5-5.5

[0100] making process:

[0101] Add 80ml of water for injection into a 200ml beaker, add tulathromycin, stir and add citric acid until dissolved, add thioglycerol, thioglycolic acid and a small amount of sodium edetate dissolved in water for injection in sequence, and use HCL or NaOH Adjust the pH of the solution to 4.5-5.5, and dilute to the mark with water for injection. The resulting solution was a colorless to light yellow clear solution.

Embodiment 2

[0103] Telamectin-flunixin meglumine compound injection pharmaceutical composition:

[0104] 100ml contains:

[0105] Tulathromycin: 1.0g

[0106] Flunixin meglumine: 0.83g

[0107] Citric acid: 0.15g

[0108] Thioglycerol: 0.5g

[0109] Thioglycolic acid: 0.1g

[0110] Sodium edetate: 0.5g

[0111] Water for injection to : 100ml

[0112] HCL or NaOH solution to adjust the pH to 4.5-5.5

Embodiment 3

[0114] Telamectin-flunixin meglumine compound injection pharmaceutical composition:

[0115] 100ml contains:

[0116] Tulathromycin: 35.0g

[0117] Flunixin meglumine: 29.05g

[0118] Citric acid: 0.15g

[0119] Thioglycerol: 0.5g

[0120] Thioglycolic acid: 0.1g

[0121] Sodium edetate: 0.5g

[0122] Water for injection to : 100ml

[0123] HCL or NaOH solution to adjust the pH to 4.5-5.5

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PUM

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Abstract

The invention relates to a compound injection medicament compound for curing the respiratory diseases of animals, in particular to a compound injection medicament compound which is used for curing the respiratory diseases of pigs and cows and contains tara zymoid and non-steroidal analgesics of effective amount.

Description

Technical field: [0001] The invention relates to a compound injection pharmaceutical composition for treating animal respiratory diseases, in particular to a compound injection pharmaceutical composition for treating swine and cattle respiratory diseases. Background technique: [0002] Respiratory diseases are one of the more difficult-to-control infectious diseases in animal husbandry. They are seriously harmful to animal husbandry and cause huge economic losses worldwide. In China, the annual losses of pig and cattle industries due to respiratory diseases amount to hundreds of billions Yuan. The economic losses caused are mainly due to respiratory diseases that easily lead to the death of animals, weight loss, decreased milk production, and huge treatment costs and reduction in feeding efficiency. [0003] Swine respiratory disease, also known as swine respiratory disease complex (SRDC), is a general term for respiratory diseases caused by multiple factors. It is caused b...

Claims

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Application Information

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IPC IPC(8): A61K31/7052A61K9/08A61K45/00A61K31/44A61P11/00
Inventor 殷生章王巧玲
Owner QINGDAO VLAND BIOTECH INC
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