Compound preparation of fructus schisandrae and evening primrose CO* supercritical extract and preparation process

A technology of supercritical extracts and compound preparations, which is applied in the direction of drug combinations, plant raw materials, and medical preparations containing active ingredients. Significant curative effect, no adverse reactions

Inactive Publication Date: 2009-11-11
赵景辉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There is no report on the compound preparation of Schisandra chinensis and evening primrose after retrieval

Method used

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  • Compound preparation of fructus schisandrae and evening primrose CO* supercritical extract and preparation process
  • Compound preparation of fructus schisandrae and evening primrose CO* supercritical extract and preparation process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Crush the fruit of Schisandra chinensis to 40 mesh and put it into CO 2 In a supercritical extraction device, with a pressure of 35 MPa; an extraction temperature of 40 ° C; 2 L / min; extraction for 3 hours to obtain Schisandra CO 2 supercritical extract.

[0048] Crush the evening primrose seeds to 40 mesh and put in CO 2 In a supercritical extraction device, with a pressure of 35MPa; extraction temperature of 35°C, separation temperature of 35°C; 2L / min; extraction for 2.5 hours to obtain evening primrose CO 2 supercritical extract.

[0049] Schisandra CO 2 Supercritical extract is 52kg, evening primrose seed CO2 47kg of the supercritical extract and 1.0kg of vitamin E are put into the batching tank, stirred and mixed evenly, and sent into the soft capsule packaging machine to press the pellets.

Embodiment 2

[0051] Crush the fruit of Schisandra chinensis to 60 mesh and put it into CO 2 In a supercritical extraction device, with a pressure of 35 MPa; an extraction temperature of 40 ° C; 2 L / min; extraction for 3 hours to obtain Schisandra CO 2 supercritical extract.

[0052] Crush the evening primrose seeds to 60 mesh and put them in CO 2 In a supercritical extraction device, with a pressure of 35MPa; extraction temperature of 35°C, separation temperature of 35°C; 2L / min; extraction for 2.5 hours to obtain evening primrose CO 2 supercritical extract.

[0053] Schisandra CO 2 Supercritical extract is 51kg, evening primrose seed CO 2 48kg of the supercritical extract and 1.0kg of vitamin E are put into a batching tank, stirred and mixed evenly, and then sent into a soft capsule packaging machine to press pills.

Embodiment 3

[0055] Crush the fruit of Schisandra chinensis to 50 mesh and put it into CO 2 In a supercritical extraction device, with a pressure of 35 MPa; an extraction temperature of 40 ° C; 2 L / min; extraction for 3 hours to obtain Schisandra CO 2 supercritical extract.

[0056] Crush the evening primrose seeds to 50 mesh and put them in CO 2 In a supercritical extraction device, with a pressure of 35MPa; extraction temperature of 35°C, separation temperature of 35°C; 2L / min; extraction for 2.5 hours to obtain evening primrose CO 2 supercritical extract.

[0057] Schisandra CO 2 Supercritical extract is 50kg, evening primrose seed CO 2 49kg of the supercritical extract and 1.0kg of vitamin E are put into the batching tank, stirred and mixed evenly, and sent into the soft capsule packaging machine to press the pellets.

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Abstract

The invention relates to a compound preparation of fructus schisandrae and evening primrose CO2 supercritical extract and a preparation process. The process is characterized by: grinding fruit of fructus schisandrae and seeds of evening primrose respectively to 40-60 meshes and putting the ground substances in a supercritical extraction device for extraction with the pressure being 35MPa, the temperature being 35-40 DEG C, and the speed being 2L / min; and subsequently obtaining the fructus schisandrae and evening primrose CO2 supercritical extract by extracting 2.5-3h; and according to parts by weight, putting 50-52 of the fructus schisandrae CO2 supercritical extract, 47-49 of the evening primrose CO2 supercritical extract and 1.0 of vitamin E in a mixture tank to be stirred, mixed evenly and delivered to a soft capsule packing machine for pelleting. The compound preparation is advanced in dosage form, guarantees lasting efficacy of effective ingredients, is low in the content of impurities and high in the content of the effective ingredients with active ingredients easily being absorbed, and is safer for eating and is a natural health food with CO2 used as extraction dissolvent and no residue of organic solvent.

Description

Technical field: [0001] The invention discloses a kind of northern schisandra and evening primrose CO 2 The supercritical extract compound preparation is a food with functions of protecting pancreatic islet cells and assisting in lowering blood sugar. The invention also discloses a preparation process of the compound preparation, which belongs to the technical field of health care products. Background technique: [0002] Schisandra is the fruit of Magnoliaceae Schisandra (Fructus Schisandrae Chinensis). Scientific research shows that Schisandra chinensis has different effects due to different origins in the north and the south. Southern schisandra is red in color, which can treat cough due to wind-cold, and northern schisandra is black in color, which can treat symptoms such as body deficiency, sweating, and impaired essence. Schisandra fruit juice, Schisandra fruit juice, Schisandra fruit jelly, Schisandra fruit wine, etc. have been developed. The common dosage forms of m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/57A61K9/48A61P3/10A61K31/355
Inventor 赵景辉王英平张瑞孙成贺刘继永焉石赵明忠韩春丽郭崇民
Owner 赵景辉
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