Filter and pipeline system used for cerebrospinal fluid purification device
A purification device and cerebrospinal fluid technology, applied in dialysis systems, chemical instruments and methods, suction devices, etc., can solve problems such as inapplicable clinical requirements, interface pollution, and heavy workload of doctors, so as to meet clinical requirements and increase filtration area, not easy to clog the effect of the filter membrane
Inactive Publication Date: 2012-06-27
王拥军 +5
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[0003] The purification of autologous cerebrospinal fluid has been a problem that has plagued clinical medical treatment for many years, mainly because the total amount of cerebrospinal fluid in the human body is only 70-160ml. The infusion volume is only 10-20ml, and the extraction and reinfusion time is relatively slow, so the minimum storage capacity of the pipeline of the treatment system is required to be as small as possible. The traditional filter is a single-membrane structure, such as figure 1 The two-chamber and two-port type shown mainly consists of two chambers consisting of an outer casing 103 and an internal filter membrane 104. The cerebrospinal fluid enters through the inlet port 102, and after being filtered by the filter membrane 104, germs and blood cells therein are removed, and then the cerebrospinal fluid flows through the outlet port 101. Outflow, in order to ensure that the mesh of the filter membrane will not be gradually blocked and affect the filtration, the area of the filter membrane must be made large, which results in a large volume and structure of the filter, which is not suitable for the clinical requirements of cerebrospinal fluid filtration
[0004] In addition, there is no single-use pipeline for cerebrospinal fluid replacement and purification in clinical practice, such as the cerebrospinal fluid purification device disclosed in Chinese patent 200520110390.4. In the existing operations, the pipeline system is temporarily built to realize the purification treatment of the cerebrospinal fluid of the instrument Operation, using common pipelines, joints, and filters to form a temporary system, the doctor’s workload is heavy during the connection of pipelines and operations, and the chance of interface contamination increases
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[0025] Such as figure 2 As shown, the filter for the cerebrospinal fluid purification device of the present invention includes a polycarbonate shell 21 and a filter element 23. The filter element 23 can adopt polyethersulfone hollow fiber membranes, and about 2000 of them are arranged in parallel, and the membrane pores are 80° To 100A°, both ends are fixed and sealed with polyurethane glue 22. The structure is three chambers and three ports. The three ports are the cerebrospinal fluid purification outlet 24, the cerebrospinal fluid outlet 25, and the cerebrospinal fluid outlet 26; these three openings are respectively formed Three chambers, when in use, the cerebrospinal fluid is drawn into the inlet body through the cerebrospinal fluid inlet 25, distributed to the filter element 23, and flows out through the cerebrospinal fluid outlet 26, and at the same time, side pumping is performed at the cerebrospinal fluid purification outlet 24, and the germs and blood cells in the ce...
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The invention discloses a filter and a corresponding pipeline system used for a cerebrospinal fluid purification device. The filter comprises a casing and filter cores and adopts a three-cavity three-opening structure type, and the filter cores are hollow fibrous membranes and are in a parallel arrangement structure. In the invention, cerebrospinal fluid with pathogenic bacteria and blood cells flows in a membrane internal cavity at the time of purification operation, the purified cerebrospinal fluid is filtered out from a membrane side hole, the invention effectively filters and removes the pathogenic bacteria and the blood cells in the cerebrospinal fluid and also has the function of self cleaning, the blockage of a filter membrane is unlikely to occur, the filter area in a smaller cavity body is increased, the volume of the cerebrospinal fluid filter reaches minimum, and the clinical use requirement is met. Corresponding to the filter, a corresponding disposable pipeline system is also provided, the entire filter and the entire pipeline system are made into whole sealing connection and are matched with the existing device for disposable use, medical source type infection which can be caused by connection operation does not exist, and the clinical problems of purification, extraction and back importation of the cerebrospinal fluid can be effectively solved.
Description
technical field [0001] The invention relates to a cerebrospinal fluid external drainage replacement purification treatment device, in particular to a filter for the cerebrospinal fluid purification device and a pipeline system composed of the filter, which is applied to clinical monitoring and treatment of patients with intracranial diseases. Background technique [0002] Cerebrospinal fluid (CSF) is a colorless transparent liquid filled in the ventricular system, the central canal of the spinal cord and the subarachnoid space, containing inorganic ions, glucose and a small amount of protein, with few cells, mainly monocytes and lymphocytes , its function is equivalent to the lymph fluid in the peripheral tissue, and it plays the role of buffering, protecting, nourishing, transporting metabolites and maintaining normal intracranial pressure to the central nervous system. In clinical practice, due to traumatic brain injury, cerebral hemorrhage, cerebral hemorrhage caused by c...
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IPC IPC(8): B01D63/02A61M1/00
CPCA61M1/16B01D63/02B01D71/68
Inventor王拥军张星虎王缨吴志敏程庆伟叶文渊
Owner王拥军