Gene chip for predicting liver cancer metastasis and recurrence risk and manufacturing method and using method thereof
A technology of gene chip and liver cancer metastasis, applied in the field of gene chip
Inactive Publication Date: 2010-08-25
ZHONGSHAN HOSPITAL FUDAN UNIV
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However, there is no relevant report on liver cancer metastasis and its prediction
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Abstract
The technical scheme of the invention provides a gene chip for predicting liver cancer metastasis and recurrence risk, which comprises a substrate and a probe arranged on the substrate, wherein the probe consists of 149 genes. The gene chip for predicting the liver cancer metastasis and the recurrence risk has the advantages that: due to the adoption of genome comparison research, a large sample independently proves that a prediction model can accurately predict and evaluate the metastasis potential of liver cancer patients. Therefore, postoperative survival and metastasis, and recurrence of the patient can be accurately predicted (even early liver cancer patients can be accurately predicted). The gene chip contributes to early identifying or predicting high-risk patients so as to perform intensive monitoring and effective intervention on the high-risk patients to further prolong the life of the tumor patients.
Description
technical field The invention relates to a gene chip for predicting liver cancer metastasis and recurrence risk and a manufacturing method thereof, belonging to the technical field of gene chips. Background technique Cancer metastasis is the primary factor affecting the survival of tumor patients, and it is also an important key to conquer hepatocellular carcinoma (Hepatocellular carcinoma, HCC) (referred to as liver cancer). At present, there are no sufficiently specific and sensitive predictors and prediction models for metastasis and recurrence. Early and accurate prediction of metastasis and recurrence is the prerequisite for timely and effective prevention and treatment, and it is also the guarantee for further prolonging the survival of patients. This predictive chip can accurately predict the metastatic potential of liver cancer, so that it can accurately predict and evaluate the metastasis and recurrence risk of liver cancer patients after radical operation, and carr...
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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/68
Inventor 叶青海贾户亮钦伦秀汤钊猷
Owner ZHONGSHAN HOSPITAL FUDAN UNIV
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