Traditional Chinese medicine for senile dementia and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine for senile dementia and a preparation method thereof. The traditional Chinese medicine comprises the following raw medicinal materials: 2g of astragalus, 3g of szechuan lovage rhizome, 2g of ginkgo seed, 3g of sharpleaf galangal fruit, 3g of grassleaf sweelflag rhizome, 2g of schizandra chinensis, 5g of shelled cedar seed, 2g of himalayan teasel root, 2g of polygala root and 2g of desertliving cistanche. The method comprises the following steps of: (1) crushing four medicinal materials such as ginkgo seed and the like and performing supercritical extraction to obtain extract; (2) decocting the astragalus in water twice, and mixing, filtering and concentrating the water extract for later use; (3) decocting three medicinal materials such as himalayan teasel root and the like in water twice, mixing, filtering and concentrating the water extract, precipitating the water extract with alcohol, and standing, filtering and concentrating the water extract for later use; (4) crushing two medicinal materials such as szechuan lovage rhizome and the like, percolating the mixture with ethanol, collecting the percolate, recovering the ethanol under reduced pressure, and concentrating the ethanol for later use; (5) mixing, concentrating and drying astragalus concentrate, the concentrate of teasel root and the like and the concentrate of szechuan lovage rhizome and the like, and crushing the obtained product to obtain extract powder; and (6) adding the extract powder into the extract of supercritical extraction and auxiliary materials,and grinding the mixture to obtain powder serving as a filler to prepare soft capsules. The traditional Chinese medicine has the effects of tonifying qi, filling marrow, promoting blood circulation, removing obstruction in channels, warming kidney, nourishing heart, opening orifice and awaking brain, and can prevent and treat dementia for health care of aged people.

Description

technical field [0001] The invention relates to a traditional Chinese medicine medicament and a preparation method, in particular to a traditional Chinese medicine medicament and a preparation method for senile dementia. Background technique [0002] Entering the 21st century, the whole world is entering the age of aging, and senile dementia has become the fourth disease after cardiovascular and cerebrovascular diseases and tumors. Data show that the speed of population aging in my country is extremely rapid. At present, the number of elderly people over 60 years old in my country has reached 120 million. [0003] Senile dementia is a common degenerative disease of the central nervous system, including Alzheimer's dementia, vascular dementia, mixed dementia and other dementias. Among them, the first two are the two major types of senile dementia, accounting for more than 90% of all senile dementia patients. Alzheimer's disease (AD), also known as senile dementia, is a deme...

AI Technical Summary

Problems solved by technology

[0004] At present, the drugs for the treatment of dementia at home and abroad mainly include cholinesterase inhibitors, pro-metabolism drugs, non-steroidal anti-inflammatory drugs, antioxidants, neurovascular regulators, estrogen therapy, etc. The above drugs have certain curative effects on early and mid-stage AD , mainly for symptomatic treatment, the overall effect is not ideal, and has varying degrees of toxic and side effects, some even have heart, liver, and kidney toxicity, making it difficult for patients to accept long-term treatment