Kit for diagnosing acute exacerbation of chronic obstructive pulmonary disease

A chronic obstructive and acute exacerbation technology, applied in the biological field, can solve the problem that the pathogenesis of chronic obstructive pulmonary disease is not fully understood, and achieve the effect of simple, easy and reliable protein expression

Inactive Publication Date: 2014-09-10
ZHONGSHAN HOSPITAL FUDAN UNIV
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0003] The pathogenesis of chronic obstructive pulmonary disease is not fully understood

Method used

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  • Kit for diagnosing acute exacerbation of chronic obstructive pulmonary disease
  • Kit for diagnosing acute exacerbation of chronic obstructive pulmonary disease
  • Kit for diagnosing acute exacerbation of chronic obstructive pulmonary disease

Examples

Experimental program
Comparison scheme
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Embodiment

[0024] A kit for diagnosing the acute exacerbation of chronic obstructive pulmonary disease, comprising the following reagents:

[0025] 1. Human lymphoid tissue chemotactic cytokine (R&D Systems, model MAB3661), and its enzyme-labeled antibody (R&D Systems, model BAF366);

[0026] 2. Macrophage-derived chemokine (R&D Systems, model MAB336), and its enzyme-labeled antibody (R&D Systems, model BAF336);

[0027] 3. Betacellulin (R&D Systems, model MAB261), and its enzyme-labeled antibody (R&D Systems, model BAF261);

[0028] 4. Human skin T cell capture chemokine (R&D Systems, model MAB3761), and its enzyme-labeled antibody (R&D Systems, model BAF376)

[0029] 5. Human epithelial neutrophil activation peptide 78 (R&D Systems, model MAB654), and its enzyme-labeled antibody (R&D Systems, model BAF254)

[0030] 6. Human macrophage migration inhibitory factor (R&D Systems, model MAB289), and its enzyme-labeled antibody (R&D Systems, model BAF289)

[0031] 7. Interleukin 28A (R&D ...

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Abstract

The invention provides a kit for diagnosing acute exacerbation of a chronic obstructive pulmonary disease. The kit is characterized by comprising a cell enzyme labeled antibody of a cell factor; and the cell factor is a human lymphatic tissue chemokine (6Ckine), a macrophage-derived chemokine (MDC) and beta cytokine (BTC). In the kit, the human lymphatic tissue chemokine (6Ckine), the macrophage-derived chemokine (MDC) and the beta cytokine (BTC) are firstly provided to be main indexes of diagnosis of the acute exacerbation of the chronic obstructive pulmonary disease.

Description

technical field [0001] The invention relates to a kit for diagnosing acute exacerbation of chronic obstructive pulmonary disease, which belongs to the field of biotechnology. Background technique [0002] Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by persistent obstruction of airflow from the lungs. The disease is an underdiagnosed, life-threatening lung disease that impedes normal breathing and is not fully reversible. Its main clinical manifestations are cough, sputum production and dyspnea. As the course of the disease progresses, it can develop to also feel short of breath when walking on a flat road. Some patients have wheezing symptoms. In addition, there are systemic symptoms such as fatigue, anorexia, and weight loss. Respiratory failure or heart failure may cause corresponding symptoms during the acute attack. Because of its large number of patients, high mortality rate and heavy social and economic burden, it has become an imp...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/577G01N33/573G01N33/68
Inventor 王向东白春学陈弘
Owner ZHONGSHAN HOSPITAL FUDAN UNIV
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