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Medicament for treating myocardial ischemia in coronary heart disease and application thereof

A technology for myocardial ischemia and coronary heart disease, which is applied in the treatment of myocardial ischemia in coronary heart disease and its application field, can solve the problems of insufficient pertinence of myocardial ischemia in coronary heart disease, heavy economic burden for patients, and unsuitable for promotion and use. To achieve the effect of improving the function of circulating endothelial progenitor cells, improving microcirculation, and shortening the course of treatment

Inactive Publication Date: 2013-07-03
SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, on the one hand, these medicines have a wide variety of raw materials, which are inevitably limited by the wide and rare sources of raw materials, and because some Chinese medicinal materials are expensive, they will bring heavy economic burdens to patients, and are not suitable for popularization. The specificity of ischemia is not strong or the effect is not significant. Therefore, there is an urgent need for a drug with few components, significant effect in treating myocardial ischemia in coronary heart disease, and easy-to-obtain raw materials
However, there are no reports about these drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Preparation of Oral Solution of Drug 1 for the Treatment of Myocardial Ischemia in Coronary Heart Disease (1)

[0026] Take 20 parts of astragalus, 4 parts of scorpion, and 4 parts of centipede, put them in a decoction container, add 5 times the amount of water to soak for 1 hour, boil for 30 minutes, and filter. Add 4 times the amount of water to the dregs and continue to decoct, boil for 20 minutes, and filter. The two filtrates were combined, concentrated on a water bath to a liquid medicine equivalent to 0.01g / ml of the original medicinal material, cooled and filled into sterilized medicine bottles, and placed in a 4°C refrigerator for later use.

Embodiment 2

[0028] Preparation of Oral Solution of Drug 1 for the Treatment of Myocardial Ischemia in Coronary Heart Disease (2)

[0029] Take 40 parts of Astragalus membranaceus, 2 parts of scorpion, and 8 parts of centipede, put them in a decoction container, add 5 times the amount of water to soak for 1 hour, boil for 30 minutes, and filter. Add 4 times the amount of water to the dregs and continue to decoct, boil for 20 minutes, and filter. The two filtrates were combined, concentrated on a water bath to a liquid medicine equivalent to 0.01g / ml of the original medicinal material, cooled and filled into sterilized medicine bottles, and placed in a 4°C refrigerator for later use.

Embodiment 3

[0031] Preparation of Oral Solution of Drug 1 for the Treatment of Myocardial Ischemia in Coronary Heart Disease (3)

[0032] Take 20 parts of Astragalus membranaceus, 4 parts of scorpion, and 8 parts of centipede, put them in a decoction container, add 5 times the amount of water to soak for 1 hour, boil for 30 minutes, and filter. Add 4 times the amount of water to the dregs and continue to decoct, boil for 20 minutes, and filter. The two filtrates were combined, concentrated on a water bath to a liquid medicine equivalent to 0.01g / ml of the original medicinal material, cooled and filled into sterilized medicine bottles, and placed in a 4°C refrigerator for later use.

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Abstract

The invention relates to a medicament for treating myocardial ischemia in coronary heart disease. The medicament is prepared from the following raw material medicaments in parts by weight: 20-40 parts of astragalus root, 2-4 parts of buthus martensi kirsch, 4-8 parts of centipede, 10-20 parts of bitter orange, 30-60 parts of root of red-rooted salvia and 9-15 parts of peach kernel. The invention also relates to application of the medicament to preparation of medicaments for preparing the coronary heart disease, particularly aiming at the myocardial ischemia in coronary heart disease stenting.The medicament is prepared from pure traditional Chinese medicines, has an obvious curative effect for treating the coronary heart disease from symptoms and mechanism, and has the advantages of wide medicament symptomatic range, no toxic or side effect, less raw material components, rich raw materials, low cost, simple preparation process and suitability for promotion and application.

Description

technical field [0001] The invention relates to a medicine for treating myocardial ischemia of coronary heart disease and its application, in particular, it is a Chinese patent medicine prepared from Chinese herbal medicine. Background technique [0002] Coronary heart disease is one of the most common clinical diseases and frequently-occurring diseases. It is a myocardial ischemia hypoxia (angina pectoris) or myocardial Necrotic (myocardial infarction) heart disease, also known as ischemic heart disease. Most of the coronary heart disease we usually talk about is caused by myocardial ischemia and hypoxia caused by organic stenosis or blockage of arteries, also known as coronary atherosclerotic heart disease. The narrowing of the coronary arteries is mostly caused by the accumulation of fatty substances along the inner wall of the blood vessels. This process is called arteriosclerosis. When arteriosclerosis develops to a certain extent, coronary artery stenosis gradually i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/481A61K36/75A61P9/10A61K35/64A61K35/646A61K35/648
Inventor 董耀荣冯其茂陆萍王俊龙胡晓珍
Owner SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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