Traditional Chinese medicine preparation for treating gastro-esophageal reflux disease

A technology of gastroesophageal reflux and traditional Chinese medicine preparations, applied in the field of traditional Chinese medicine preparations for the treatment of gastroesophageal reflux disease, can solve problems such as the inability to improve the function of the lower esophageal sphincter, and achieve the effect of restoring epithelial barrier function, reducing content, and reducing expression

Inactive Publication Date: 2013-08-07
TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These existing Chinese patent medicines do not meet the key pathogenesis of gastroesophageal reflux disease, cannot improve the function of the lower esophageal sphincter, and cannot fundamentally solve the problem of gastroesophageal reflux

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Example 1 (kg)

[0030] Inula 15 generations ocher 5 raw sun-dried ginseng 15 Qing pinellia 10 roasted licorice 10 Sichuan coptis 18 Evodia 3 angelica 15 loquat leaves 15 bitter platycodon 3

Embodiment 2

[0031] Example 2 (kg)

[0032] Inula 10 generations ocher 10 raw sun-dried ginseng 10 Qing Pinellia 5 roasted licorice 5 Sichuan coptis 12 Evodia 6 angelica 20 loquat leaves 12 bitter platycodon 6

Embodiment 3

[0033] Example 3 (kg)

[0034] Inula 12 generations ocher 6 raw sun-dried ginseng 12 Qing Pinellia 6 roasted licorice 6 Sichuan coptis 10 Evodia 2 angelica 12 loquat leaves 10 bitter and bitter platycodon 5

[0035] The dosage form of the present invention can be decoction or granule.

[0036] The conventional preparation method of the present invention is used for production.

[0037] The research results of the present invention show that the optimal ratio of inula inula and ocher is 3:1, when the raw sun-dried ginseng is reused, the improvement of gastroesophageal reflux symptoms is the most obvious, and the recovery degree of esophageal mucosal barrier function is the best.

[0038] In addition, the optimal ratio of Chuanhuanglian and Evodia is 6:1; the optimal ratio of loquat leaves and bitter platycodon is 5:1; the dosage of angelica is at least 15g, which can be flexibly controlled according to the specific conditions of patients.

[0039] Dosage: One dose per day, deco...

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PUM

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Abstract

The invention discloses traditional Chinese chinese preparation for treating gastro-esophageal reflex disease. Raw materials include, by weight part, from 10 to 15 parts of inula flower, from 5 to 10 parts of ruddle, from 10 to 15 parts of dry radix ginseng, from 5 to 10 parts of rhizoma pinelliae preparata, from 5 to 10 parts of radix glycyrrhizae preparate, from 12 to 18 parts of Sichuan coptischinensis, from 3 to 6 parts of fructus evodiae, from 15 to 20 parts of western tangkuei, from 10 to 15 parts of loquat leaves and from 1 to 3 parts of bitter platycodon grandiflorum. Efficiency of the traditional Chinese medicine preparation reaches 92.7%, and a good curative effect is obtained.

Description

technical field [0001] The invention relates to a medicine for treating gastroesophageal reflux disease, in particular to a traditional Chinese medicine preparation using Chinese herbal medicine as a raw material for treating gastroesophageal reflux disease. Background technique [0002] Gastroesophageal reflux disease (GERD) refers to a series of chronic symptoms and esophageal mucosal damage caused by the reflux of gastric or duodenal contents into the esophagus, including non-erosive reflux esophagitis (NERD), reflux esophagitis (RE) and its complications such as esophageal stricture, hemorrhage, perforation and Barrett's esophagus (BE). The incidence of gastroesophageal reflux disease in western countries is as high as 10%-30%. Epidemiological surveys in Beijing and Shanghai in my country show that those with significant reflux symptoms are as high as 8.86%, and it has gradually increased in recent years. Gastroesophageal reflux disease has brought a huge economic burde...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8888A61P1/04A61K33/26
Inventor 袁红霞
Owner TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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