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Pharmaceutical composition with function of treating cerebrovascular diseases

A composition and drug technology, applied in the field of medicine, can solve the problems of many adverse reactions, limited clinical use, high price and the like

Active Publication Date: 2014-07-23
HAINAN BIKAI PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, although the clinically recommended antithrombotic drugs are effective, they have many adverse reactions and are expensive, which limits their clinical use.

Method used

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  • Pharmaceutical composition with function of treating cerebrovascular diseases
  • Pharmaceutical composition with function of treating cerebrovascular diseases
  • Pharmaceutical composition with function of treating cerebrovascular diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] A pharmaceutical composition, comprising 19 g of ozagrel sodium and 1 g of 1,3-diaza-2,4-cyclopentadiene in the pharmaceutical composition.

[0091] The above pharmaceutical composition is used for treating thrombosis. The above pharmaceutical composition is used for treating acute thrombotic cerebral infarction and the movement disorder accompanied by cerebral infarction.

[0092] The above pharmaceutical composition is prepared into 1000 water injections or powder injections according to the prior art.

Embodiment 2

[0094] A pharmaceutical composition, comprising 19.2 g of ozagrel sodium and 0.8 g of 1,3-diaza-2,4-cyclopentadiene in the pharmaceutical composition.

[0095] The above pharmaceutical composition is used for treating thrombosis. The above pharmaceutical composition is used for treating acute thrombotic cerebral infarction and the movement disorder accompanied by cerebral infarction.

[0096] The above pharmaceutical composition is prepared into 1000 water injections or powder injections according to the prior art.

Embodiment 3

[0098] A pharmaceutical composition, comprising 19.6 g of ozagrel sodium and 0.4 g of 1,3-diaza-2,4-cyclopentadiene in the pharmaceutical composition.

[0099] The above pharmaceutical composition is used for treating thrombosis. The above pharmaceutical composition is used for treating acute thrombotic cerebral infarction and the movement disorder accompanied by cerebral infarction.

[0100] The above pharmaceutical composition is prepared into 1000 water injections or powder injections according to the prior art.

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Abstract

The invention belongs to the technical field of medicine and particularly relates to a pharmaceutical composition with function of treating cerebrovascular diseases. The pharmaceutical composition contains ozagrel sodium and 1, 3-diaza-2, 4-cyclopentadiene, wherein the weight percentage of the ozagrel sodium is more than or equal to 95 percent and less than 100 percent, and the weight percentage of the 1, 3-diaza-2, 4-cyclopentadiene is more than zero and less than or equal to 5 percent. The pharmaceutical composition provided by the invention is determined by pharmacology experiment and toxicology experiment.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition containing ozagrel sodium. Background technique [0002] A thrombus is a small piece of blood that forms on the surface of a vessel in the cardiovascular system where the lining has been peeled off or repaired. In variable flow dependent patterns, thrombus consists of insoluble fibrin, deposited platelets, accumulated leukocytes, and trapped red blood cells, and thrombosis is a process involving many genetic and environmental factors interacting with each other The process of multifactorial changes, clinically common patients with thrombosis diathesis, the most important features are family history, recurrent, young, severity of attack symptoms, and unusual site of thrombosis. Arterial or venous thrombosis or thromboembolism requires objective evidence. Angiography is the reference standard for diagnosis. Ultrasound detection with skillf...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/4174A61K31/4164A61P7/02A61P9/10A61P25/14
Inventor 陈容徐扬冯仲异史朝辉
Owner HAINAN BIKAI PHARM CO LTD
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