Preparation method of licorice particles for livestock and poultry

Abstract

The invention discloses a preparation method of licorice particles for livestock and poultry, comprising the following steps of: firstly taking licorice, placing it into an extraction pot to form a medicinal material layer, adding water and immersing, adjusting the operating temperature of the extraction pot to 60-80 DEG C for extraction, leading out parts of an extract from the bottom of the extraction pot during the extraction process and carrying out vacuum concentration while the concentration temperature is 50-70 DEG C, condensing steam generated by the concentration, returning the stream used as a new solvent into the extraction pot for permeating extraction of the medicinal material layer, continuously repeating for 2-3 hours, condensing to finally obtain a fluid extract, adding anhydrous glucose and maltodextrin or cyclodextrin and the fluid extract into a spray drying granulator, and carrying out granulation so as to obtain the licorice particles for livestock and poultry. According to the preparation method of the licorice particles for livestock and poultry, the two processes of licorice extraction and condensation are synchronously carried out so as to change a high-temperature decocting technology of a traditional extraction pot under pressure and at normal pressure. Therefore, energy can be saved by 0.3-0.5 time; the amount of a hydrosolvent is minimized by 0.5-1 time; the feeding amount is increased by 30-60%; extract yielding rate is raised by more than 10%; the storage process is minimized; and electric power energy is saved by more than 30%.

Description

technical field [0001] The invention relates to a preparation method of licorice granules for livestock and poultry, and belongs to the technical field of veterinary medicine. Background technique [0002] Traditional Chinese medicine granule (granula) is a new dosage form developed on the basis of decoction and syrup. It not only maintains the characteristics of fast absorption and rapid action of decoction, but also overcomes the inconvenience of decoction and large dosage. It is very suitable for clinical drug administration in modern and intensive farms. It has the advantages of good palatability, small dosage, rapid drug effect, controllable quality, good stability, and convenient storage, transportation and carrying. [0003] Licorice granule is a single pure traditional Chinese medicine preparation for livestock and poultry. It has the functions of eliminating phlegm, relieving cough, anti-inflammation and detoxification. It has a significant effect on respiratory di...

AI Technical Summary

Problems solved by technology

[0004] At present, the commonly used preparation methods of licorice granules include traditional water-alcohol extraction method and wet granulation method, which have many disadvantages, such as large loss of active ingredients, low content, difficult operation of post-production process, long production cycle, serious pollution in the production process, and violation of GMP requirements, etc.

Patent No. CN101474244A discloses a formula granule of roasted licorice and its preparation method and quality control method, which provides a good quality control method, but in the process of pre-production, the method of second decoction is still equivalent to the traditional The unique decoction extraction method prolongs the extraction time and cumbersome operating procedures

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